When Reuben Tarz and Daniel Bishop met, they were hardly more than boys. Twenty years later, Reuben is a Hollywood mogul and Daniel has become a renowned Washington D.C. lawyer. Life has rewarded both with riches, success, and beautiful wives, if not always contentment. Out of the blue, an urgent telephone call from Mickey summons Daniel to France to rescue Philippe, the son Reuben never knew existed, and bring him to America.

At 29, Alison Marshall is ready to find a place to call home. With no family and no ties, she’s drifted from one small Florida town to another since high school, working odd jobs, saving hard, and building a nest egg. Once she finds the right place to settle down, she’ll know. And when she reaches beautiful Palmetto Island, she thinks she may have found it. The small, close-knit island community seems to have everything Alison needs. On a hunch, she contacts the island’s only realtor, and learns that an old beach house is on the market.

Mateo Castillo is a rising star chef on the Manhattan culinary scene. But just as he’s about to reap the rewards of his skill and hard work by being featured on a major TV cooking competition, Mateo collapses in his restaurant’s kitchen—and regains consciousness in a hospital emergency room. If it weren’t for a security guard finding him in time, Mateo would have bled to death. The cause of his sudden illness is as mysterious as it is worrying, and Mateo and his family undergo a battery of genetic tests. Yet the answers that start to emerge only raise more questions.

Olivia Lowell always believed her father's claim that her mother died in childbirth, until the shocking day a lawyer informs her that her mother has just passed away, leaving her a fortune. The money comes with a caveat - and a confession. In her will, Olivia's mother reveals that she and two college friends committed a crime long ago, and now she wants Olivia to track down her accomplices and convince them to come clean.

If her abusive husband hadn't tried to kill her and her beloved dog Lucie, Helen Ward might never have left her million-dollar home and run far away. Now Helen's changed her identity and moved across the country, hopeful that she can be safe, happy, maybe even loved. And when she meets college professor Sam Tolliver, she begins to believe fairytales do come true.

After years of standing by their women, the Sisterhood's significant others have also become loyal friends. And now Jack Emery, Nikki's husband, has enlisted Ted, Joe, Jay, Bert, Dennis, and Abner to form a top-secret organization known as BOLO Consultants.

On the surface, these seven women are as different as can be - but each has had her share of bad luck, from cheating husbands to sexist colleagues to a legal system that often doesn't do its job. Now, drawn together by tragedy, they're forging a bond that will help them right the wrongs committed against them and discover an inner strength they didn't know they had. The Sisterhood is learning that when bad things happen, you can roll over and play dead...or you can get up fighting...

On his thirty-fifth birthday, Jake St. Cloud inherits a fortune - and learns the whereabouts of his mysterious half-brother. On her deathbed, Selma St. Cloud revealed that Jake had a sibling, a product of his father's affair. At last, Jake is in a position to track down Alex Rosario and make amends for their father's past neglect.

College senior Lily Madison is on her own and desperate to pay for her last semester of school. With nowhere to turn, she makes the difficult decision to donate her eggs to a fertility clinic. Sam Parker is also a penniless student who supplements his tuition money by visiting a sperm bank. One day, Lily and Sam meet at the clinic and talk about their secret. Despite their obvious attraction, Lily and Sam go their separate ways.

Back in college, Jane Lewis would have given anything to be like homecoming queen Connie Bryan. Instead she was just Plain Jane - overweight, frumpy, and painfully shy. That was then. Today, a lovely and confident Dr. Jane Lewis has a thriving psychotherapy practice, her own radio talk show, a beautiful old Louisiana mansion, and her affectionate, nutty dog, Olive, to keep her company. The only thing missing is someone to share her life.

Raised on her father's South Carolina plantation, Callie Parker wanted for nothing, and now she is about to marry wealthy local scion Wyn Archer. But her wedding wouldn't be complete without the three people she grew up with under the sheltering branches of the angel oaks at Parker Manor.

Teresa "Toots" Amelia Loudenberry has crammed a great deal of living - not to mention eight much-loved husbands - into her varied and rewarding life. Newly single, Toots is ready to taste life again, and fate has just handed her the perfect opportunity.

With a heart full of dreams, Sallie Coleman leaves Texas and heads west determined to get as far from the squalor of her dirt poor beginnings. With its shifting sands, smoky saloons, and bingo palaces, Las Vegas seems like a paradise. A paradise where an extraordinary twist of fate makes Sallie the most powerful businesswoman in Nevada.

Emily Ammerman has always felt at home amid the ski runs and slopes of Snowdrift Summit, the Colorado resort her family has operated for decades. Snow is her element, and she doesn’t hesitate when a new client asks her to train him to ski The Plunge, one of Colorado’s most treacherous runs. But Zach Ryder is no regular client. On screen, he’s famous for starring as a daring CIA officer who always saves the day. In real life, he’s just as handsome and charming as his alter ego, though not everyone is impressed.

Raised in a magnificent Charleston house, Jessie Roland wants for nothing. But as she grows into young adulthood, all she feels is loss and a desperate need to break free from the stifling possessiveness of her parents. Somewhere, in the deepest part of herself, Jessie believes that the world she has always lived in is not the one she came from...or belongs in. Now, at 19, she has escaped to Washington, DC, where no one knows her, and where she is swept into a whirlwind marriage to a Texas senator's son.