-
A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- Narrado por: Erin Bennett
- Duración: 9 h y 22 m
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Resumen del Editor
A trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril.
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American taxpayers spend $30 billion annually funding biomedical research, but over half of these studies can't be replicated due to poor experimental design, improper methods, and sloppy statistics. Bad science doesn't just hold back medical progress, it can sign the equivalent of a death sentence for terminal patients. In Rigor Mortis, Richard Harris explores these urgent issues with vivid anecdotes, personal stories, and interviews with the top biomedical researchers. We need to fix our dysfunctional biomedical system - before it's too late.
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Eye opening introduction to biomedical R&D
- De Amazon Customer en 09-18-18
De: Richard Harris
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The Deeper Genome
- Why There Is More to the Human Genome than Meets the Eye
- De: John Parrington
- Narrado por: John Lee
- Duración: 9 h
- Versión completa
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Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.
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Great Scientific Writing/ Wrong Narrator
- De Richard en 11-24-15
De: John Parrington
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Creation
- How Science Is Reinventing Life Itself
- De: Adam Rutherford
- Narrado por: Walter Dixon
- Duración: 6 h y 53 m
- Versión completa
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What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.
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The Goldilocks book on what is life
- De Gary en 07-11-13
De: Adam Rutherford
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Happy Accidents
- Serendipity in Major Medical Breakthroughs in the Twentieth Century
- De: Morton A. Meyers
- Narrado por: Richard Waterhouse
- Duración: 12 h y 37 m
- Versión completa
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Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the 20th century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!
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Don't waste your money!
- De Amazon Customer en 03-20-16
De: Morton A. Meyers
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Welcome to the Microbiome
- Getting to Know the Trillions of Bacteria and Other Microbes In, On, and Around You
- De: Rob DeSalle, Susan L. Perkins
- Narrado por: Stephen McLaughlin
- Duración: 7 h y 25 m
- Versión completa
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Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.
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I learned so much from this book. I am happy.
- De Jonathan Miller en 09-08-18
De: Rob DeSalle, y otros
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Denialism
- How Irrational Thinking Hinders Scientific Progress, Harms the Planet, and Threatens Our Lives
- De: Michael Specter
- Narrado por: Richard Poe
- Duración: 8 h y 33 m
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New Yorker staff writer Michael Specter has twice won the Global Health Council’s Excellence in Media Award, as well as the Science Journalism Award from the American Association for the Advancement of Science. In Denialism, he fervently argues that people are turning away from new technologies and engaging in a kind of magical thinking that is hindering scientific progress.
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A compelling read
- De S en 05-17-11
De: Michael Specter
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An Epidemic of Absence
- A New Way of Understanding Allergies and Autoimmune Diseases
- De: Moises Velasquez-Manoff
- Narrado por: Chris Sorensen
- Duración: 17 h y 6 m
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An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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The point of view from a Veterinarian immunologist
- De rtgymnast en 11-03-17
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The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
- De: George Johnson
- Narrado por: Arthur Morey
- Duración: 8 h y 19 m
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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
- De Digital Dilema en 09-06-13
De: George Johnson
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Missing Microbes
- How the Overuse of Antibiotics Is Fueling Our Modern Plagues
- De: Martin J. Blaser
- Narrado por: Patrick Lawlor
- Duración: 8 h y 43 m
- Versión completa
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In Missing Microbes, Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now this invisible eden is being irrevocably damaged by some of our most revered medical advances-antibiotics-threatening the extinction of our irreplaceable microbes with terrible health consequences.
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Very enlightening and information well supported
- De James en 05-03-15
De: Martin J. Blaser
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The Emperor of All Maladies
- A Biography of Cancer
- De: Siddhartha Mukherjee
- Narrado por: Fred Sanders
- Duración: 22 h y 18 m
- Versión completa
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The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".
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Incredible
- De S.R.E. en 03-02-16
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Neanderthal Man
- In Search of Lost Genomes
- De: Svante Pääbo
- Narrado por: Dennis Holland
- Duración: 10 h y 36 m
- Versión completa
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A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.
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Excellent science tale
- De Neuron en 01-19-15
De: Svante Pääbo
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Viruses, Plagues, and History
- Past, Present, and Future
- De: Michael B. A. Oldstone
- Narrado por: L.J. Ganser
- Duración: 13 h y 38 m
- Versión completa
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Historia
The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.
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very detailed, but very statistical
- De ekhensel15 en 01-12-19
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Rosalind Franklin
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Rosalind Franklin was what can only be called an overlooked genius. Although she was not fully credited for the feat at the time, her work led to major breakthroughs in our understanding of DNA. In fact, she took the first X-ray photo of DNA in all of its double helix glory. By the time her former colleagues were being showered with accolades for results they made at least partially based on her findings, Franklin would not be around to see it. Sadly, it’s believed that her use of X-ray equipment gave her terminal cancer, cutting her life short at age 37.
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While cells are commonly considered the building block of living things, it is actually the communication between cells that brings us to life, controlling our bodies and brains, determining whether we are healthy or sick, and directly influencing how we think, feel, and behave. In The Secret Language of Cells, doctor and neuroscientist Jon Lieff lets us listen in on these conversations, and reveals their significance for everything from mental health to cancer.
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The cells in our bodies consist of molecules, made up of the same carbon, oxygen, and hydrogen atoms found in air and rocks. But molecules, such as water and sugar, are not alive. So how do our cells - assemblies of otherwise "dead" molecules - come to life, and together constitute a living being? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale.
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For biologists to learn single molecule biophysics
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The Genesis Machine
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Synthetic biology promises to reveal how life is created and how it can be re-created, enabling scientists to rewrite the rules of our reality. It could help us, for example, heal without prescription medications, grow meat without harvesting animals, or confront our looming climate catastrophe. Synthetic biology will determine the ways in which we conceive future generations and how we define family, how we identify disease and treat aging, where we make our homes, and how we nourish ourselves.
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Thought provoking but politically biased
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In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.
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Brilliant! But please update!
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The Lives of a Cell
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In The Lives of a Cell, Dr. Lewis Thomas opens up to the listener a universe of knowledge and perception that is perhaps not wholly unfamiliar to the research scientist; but the world he explores is also one of men and women, of complex interrelationships, old ironies, peculiar powers, and intricate languages that give identity to the alienated and direction to the dependent. This remarkable work offers a subtle, bold vision of humankind and the world around us - a sense of what gives life - from a writer who seems to draw grace and strength from the very substance of his subject.
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So enlightening and enjoyable!
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The Double Helix
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- De: James D. Watson
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By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.
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Star for Watson, Crick, Wilkins, AND for FRANKLIN
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Genome
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- De: Matt Ridley
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- Grabación Original
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Arguably the most significant scientific discovery of the new century, the mapping of the 23 pairs of chromosomes that make up the human genome raises almost as many questions as it answers - questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Matt Ridley here probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome.
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Still useful today.
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De: Matt Ridley
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Ancient Bones
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- De: Madelaine Böhme
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Africa has long been considered the cradle of life - where life and humans evolved - but somewhere west of Munich, Germany, paleoclimatologist and paleontologist Madelaine Böhme and her team make a discovery that is beyond anything they ever imagined: the 12-million-year-old bones of an ancient ape - Danuvius guggenmos - which makes headlines around the world and defies prevailing theories of human history and where human life began.
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Brave Attempt
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Lo que los oyentes dicen sobre A Crack in Creation
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- S.Knox
- 01-12-18
Interesting subject matter but not much meat.
The subject is fascinating and the behind the scenes look at the developments leading up to Crispr were very interesting. Most of the book reads like a Nobel application, carefully acknowledging the contributions of others while preserving the authors preeminent role.
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Historia
- Mike Hayward
- 09-17-19
Amateur Delivery, Good Content
I learned a number of very interesting things from this book, but it required a bit of slogging. The author devotes significant time to recounting and dramatizing personal encounters, perhaps to lay claim to discoveries or convey her self image, which I found to be tedious and distracting. In other areas of the book she discusses discoveries, developments, implications, possibilities, and her opinions which were generally to the point and well thought out. I am thankful for the audio format as it allows me to glaze over during the sections which should have been edited out on my regular drive to work. I recommend this book if you know nothing about CRISPER, however there may be better, or more succinct books out there.
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- keith Lemmons
- 03-26-21
WowThe film Gattaca is no longer science fiction!
Such an incredible look into the present & future of human heath and science.
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- PB.
- 01-22-24
Science capture
Scientists, the schools that produce them and what they choose to research are controlled by those who fund them. In this day and age science and scientists are bought and payed for by big pharma and our hopelessly corrupt self serving politicians in our federal government. Never ever trust any of them.
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- Thirsty Mind
- 07-05-18
An education for lay people in genetics issues
As a person interested in genetic modification issues but without a science degree, I found this book super informative. It was technically rich enough to not gloss over anything yet still made the field feel transparent to a lay person.
This is for people on both sides of any controversy about genetic engineering. Also well-delivered by the narrator.
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- Luke
- 01-22-19
Must Read!
Incredible insight into scientific research on CRSPR! It has motivated me to look for further and into more research, yet to come.
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- Tim
- 09-14-19
Candid and Insightful Overview
Goes into the mechanics and their implications, the better part of the first half of the book is devoted to bringing listeners up to speed on the techniques, and it is quite informative; philosophically, the latter half of the book is quite sound, with some of the best thinking on what actually can possibly happen with these advancements, and how monumental they are; who better to do such important thinking on the subject than the very creators of the advancements?
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- Chris Reich
- 02-20-19
Stayed Up All Night
The only thing I did not like about this book is that it kept me up all night.
Hands down, the best science book I have purchased and there are many. This book is fascinating and perfectly paced. If you like science you will love this superb book.
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- Sam
- 01-30-22
A Popular Life Science Title
When popular science titles all meaning to Astronomy, Particle, string theory and High Energy physics based titles, this title is meanwhile very narrowly based on CRISPR by the Nobel laureate. We expect to see such titles on different scientific subjects.
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- Jan D. Leslie
- 07-22-17
Amazing
what a wonderful book. Enthusiastically describes an incredible new level of understanding. As well as how the tools that come with it can make all our genetic dreams, and nighmares, come true.
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