From Breakthrough to Blockbuster
The Business of Biotechnology
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Narrado por:
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Chris Andrew Ciulla
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Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources.
Biotech companies have met the challenge by creating nearly 40% more of the most important treatments for previously unmet medical needs. Moreover, they have done so with much lower overall costs.
From Breakthrough to Blockbuster focuses on both the companies themselves and the broader biotech ecosystem that supports them. It paints a portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies, demonstrating how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions.
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- Narrado por: Sean Runnette
- Duración: 7 h y 27 m
- Versión completa
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Since its first publication, Michael J. Mauboussin's popular guide to wise investing has been translated into eight languages and has been named best business book by BusinessWeek and best economics book by Strategy+Business. Now updated to reflect current research and expanded to include new chapters on investment philosophy, psychology, and strategy and science as they pertain to money management.
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Liked it better when it was written by Taleb
- De Ian en 11-24-18
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Lead and Disrupt
- How to Solve the Innovator's Dilemma
- De: Charles A. O'Reilly III, Michael L. Tushman
- Narrado por: James Foster
- Duración: 8 h y 36 m
- Versión completa
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In the past few years, a number of well-known firms have failed; think of Blockbuster, Kodak, or RadioShack. When we hear about their demise, it often seems inevitable - a natural part of "creative destruction." But closer examination reveals a disturbing truth: Companies large and small are shuttering more quickly than ever. What does it take to buck this trend? The simple answer is: ambidexterity. Firms must remain competitive in their core markets, while also winning in new domains.
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Very very inspirational to me.
- De Fábio en 06-12-17
De: Charles A. O'Reilly III, y otros
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Born to Build
- How to Build a Thriving Startup, a Winning Team, New Customers and Your Best Life Imaginable
- De: Jim Clifton, Sangeeta Badal
- Narrado por: Braden Wright
- Duración: 3 h y 47 m
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Written for anyone trying to figure out how to make the most of their lives, Born to Build seeks to inspire entrepreneurs and ambitious, self-motivated people to build something that will change the world. A builder’s venture could be a small business that grows into a mammoth enterprise, a thriving new division in an existing company, a nonprofit, a social enterprise, a church, a school - anything that creates economic growth and makes a lasting impact on society.
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Powerful perspective shift
- De Diana_loves_audiobooks en 06-09-18
De: Jim Clifton, y otros
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Engine of Impact
- Essentials of Strategic Leadership in the Nonprofit Sector
- De: William F. Meehan III, Kim Starkey Jonker
- Narrado por: C. J. Lengua
- Duración: 7 h y 32 m
- Versión completa
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We are entering a new era - an era of impact. The largest intergenerational transfer of wealth in history will soon be underway, bringing with it the potential for huge increases in philanthropic funding. Engine of Impact shows how nonprofits can apply the principles of strategic leadership to attract greater financial support and leverage that funding to maximum effect.
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Must listen for all nonprofit leaders
- De Peter A. Mello en 02-09-19
De: William F. Meehan III, y otros
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Machine, Platform, Crowd
- Harnessing Our Digital Future
- De: Erik Brynjolfsson, Andrew McAfee
- Narrado por: Jeff Cummings
- Duración: 10 h y 57 m
- Versión completa
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In The Second Machine Age, Andrew McAfee and Erik Brynjolfsson predicted some of the far-reaching effects of digital technologies on our lives and businesses. Now they’ve written a guide to help listeners make the most of our collective future. Machine | Platform | Crowd outlines the opportunities and challenges inherent in the science fiction technologies that have come to life in recent years, like self-driving cars and 3D printers, online platforms for renting outfits and scheduling workouts, or crowd-sourced medical research and financial instruments.
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Both How AND Why for Techies
- De Dan Collins en 08-11-17
De: Erik Brynjolfsson, y otros
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Economics for the Common Good
- De: Jean Tirole, Steven Rendell - translator
- Narrado por: Jonathan Davis
- Duración: 18 h y 54 m
- Versión completa
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When Jean Tirole won the 2014 Nobel Prize in Economics, he suddenly found himself being stopped in the street by complete strangers and asked to comment on issues of the day, no matter how distant from his own areas of research. His transformation from academic economist to public intellectual prompted him to reflect further on the role economists and their discipline play in society. The result is Economics for the Common Good, a passionate manifesto for a world in which economics, far from being a "dismal science," is a positive force for the common good.
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A Great Overview of the Challenges of Modern Econ
- De Zach Sullivan en 08-06-18
De: Jean Tirole, y otros
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Power and Prediction
- The Disruptive Economics of Artificial Intelligence
- De: Ajay Agrawal, Joshua Gans, Avi Goldfarb
- Narrado por: Tom Beyer
- Duración: 10 h y 7 m
- Versión completa
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In their bestselling first book, Prediction Machines, eminent economists Ajay Agrawal, Joshua Gans, and Avi Goldfarb explained the simple yet game-changing economics of AI. Now, in Power and Prediction, they go deeper, examining the most basic unit of analysis: the decision. The authors explain that the two key decision-making ingredients are prediction and judgment, and we perform both together in our minds, often without realizing it.
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Inspire system thinking with informative examples
- De Lucy A. Pithecus en 11-16-22
De: Ajay Agrawal, y otros
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Competition Demystified
- A Radically Simplified Approach to Business Strategy
- De: Judd Kahn, Bruce C. Greenwald
- Narrado por: Timothy Andrés Pabon
- Duración: 14 h y 22 m
- Versión completa
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Bruce Greenwald, one of the nation's leading business professors, presents a new and simplified approach to strategy that cuts through much of the fog that has surrounded the subject. Based on his hugely popular course at Columbia Business School, Greenwald and his co-author, Judd Kahn, offer an easy-to-follow method for understanding the competitive structure of your industry and developing an appropriate strategy for your specific position.
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Prof, we need the figures/graphs that’s in the the book
- De sid en 12-25-20
De: Judd Kahn, y otros
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Blind Spots
- Why We Fail to Do What’s Right and What to Do about It
- De: Max H. Bazerman, Ann E. Tenbrunsel
- Narrado por: Kate McQueen
- Duración: 7 h y 18 m
- Versión completa
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When confronted with an ethical dilemma, most of us like to think we would stand up for our principles. But we are not as ethical as we think we are. In Blind Spots, leading business ethicists Max Bazerman and Ann Tenbrunsel examine the ways we overestimate our ability to do what is right and how we act unethically without meaning to.
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Great book! Poor narration
- De Susie en 11-20-17
De: Max H. Bazerman, y otros
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The Billion Dollar Molecule
- One Company's Quest for the Perfect Drug
- De: Barry Werth
- Narrado por: Stephen Bowlby
- Duración: 18 h y 25 m
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Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.
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Book is interesting but narrator is not
- De Alexa en 05-05-23
De: Barry Werth
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For Blood and Money
- Billionaires, Biotech, and the Quest for a Blockbuster Drug
- De: Nathan Vardi
- Narrado por: Rob Shapiro
- Duración: 8 h y 33 m
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For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.
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Must-read for biotech enthusiasts and scientists
- De Anonymous User en 03-16-23
De: Nathan Vardi
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Genentech
- The Beginnings of Biotech
- De: Sally Smith Hughes
- Narrado por: Suzie Althens
- Duración: 7 h y 12 m
- Versión completa
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General
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In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading. Coming at a time of economic recession and declining technological competitiveness in the United States, the event ignited a period of speculative frenzy over biotechnology.
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Shallow and lifeless
- De LTS en 11-26-23
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Inside the Orphan Drug Revolution
- The Promise of Patient-Centered Biotechnology
- De: James A. Geraghty
- Narrado por: Scott Wallace
- Duración: 7 h y 39 m
- Versión completa
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Jim Geraghty has been a passionate participant in the orphan drug revolution since its inception―a leader in the field as a strategy consultant, biotechnology executive, and venture entrepreneur. His book is in part a history, with eyewitness accounts of advances as they occurred and portraits of the pioneering scientists and physicians, tireless activists, and visionary business leaders who made the revolution happen. And it tells deeply personal stories of patients and parents willing to risk untried new therapies.
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Excellent learning onorphan drugs and beyond
- De Fox2 en 08-05-24
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The Song of the Cell
- An Exploration of Medicine and the New Human
- De: Siddhartha Mukherjee
- Narrado por: Dennis Boutsikaris
- Duración: 16 h y 3 m
- Versión completa
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General
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Narración:
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Historia
From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.
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Beyond Words Wonderful
- De Lynn en 11-27-22
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Regenesis
- How Synthetic Biology Will Reinvent Nature and Ourselves
- De: George M. Church, Ed Regis
- Narrado por: Peter Lerman
- Duración: 10 h y 47 m
- Versión completa
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General
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Narración:
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Historia
In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.
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Brilliant! But please update!
- De Nick en 01-28-21
De: George M. Church, y otros
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The Billion Dollar Molecule
- One Company's Quest for the Perfect Drug
- De: Barry Werth
- Narrado por: Stephen Bowlby
- Duración: 18 h y 25 m
- Versión completa
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General
-
Narración:
-
Historia
Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.
-
-
Book is interesting but narrator is not
- De Alexa en 05-05-23
De: Barry Werth
-
For Blood and Money
- Billionaires, Biotech, and the Quest for a Blockbuster Drug
- De: Nathan Vardi
- Narrado por: Rob Shapiro
- Duración: 8 h y 33 m
- Versión completa
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General
-
Narración:
-
Historia
For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.
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Must-read for biotech enthusiasts and scientists
- De Anonymous User en 03-16-23
De: Nathan Vardi
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Genentech
- The Beginnings of Biotech
- De: Sally Smith Hughes
- Narrado por: Suzie Althens
- Duración: 7 h y 12 m
- Versión completa
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General
-
Narración:
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Historia
In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading. Coming at a time of economic recession and declining technological competitiveness in the United States, the event ignited a period of speculative frenzy over biotechnology.
-
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Shallow and lifeless
- De LTS en 11-26-23
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Inside the Orphan Drug Revolution
- The Promise of Patient-Centered Biotechnology
- De: James A. Geraghty
- Narrado por: Scott Wallace
- Duración: 7 h y 39 m
- Versión completa
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General
-
Narración:
-
Historia
Jim Geraghty has been a passionate participant in the orphan drug revolution since its inception―a leader in the field as a strategy consultant, biotechnology executive, and venture entrepreneur. His book is in part a history, with eyewitness accounts of advances as they occurred and portraits of the pioneering scientists and physicians, tireless activists, and visionary business leaders who made the revolution happen. And it tells deeply personal stories of patients and parents willing to risk untried new therapies.
-
-
Excellent learning onorphan drugs and beyond
- De Fox2 en 08-05-24
-
The Song of the Cell
- An Exploration of Medicine and the New Human
- De: Siddhartha Mukherjee
- Narrado por: Dennis Boutsikaris
- Duración: 16 h y 3 m
- Versión completa
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General
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Narración:
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Historia
From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.
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Beyond Words Wonderful
- De Lynn en 11-27-22
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Regenesis
- How Synthetic Biology Will Reinvent Nature and Ourselves
- De: George M. Church, Ed Regis
- Narrado por: Peter Lerman
- Duración: 10 h y 47 m
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General
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Narración:
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Historia
In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.
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Brilliant! But please update!
- De Nick en 01-28-21
De: George M. Church, y otros
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Immune
- A Journey into the Mysterious System That Keeps You Alive
- De: Philipp Dettmer
- Narrado por: Steve Taylor
- Duración: 10 h y 28 m
- Versión completa
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You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.
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Steve Taylor for the win
- De Bay Area Engineer en 11-02-21
De: Philipp Dettmer
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The Antidote
- Inside the World of New Pharma
- De: Barry Werth
- Narrado por: Sean Pratt
- Duración: 16 h y 27 m
- Versión completa
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Historia
In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.
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For me this was not interesting
- De Yan en 06-26-17
De: Barry Werth
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Superconvergence
- How the Genetics, Biotech, and AI Revolutions Will Transform our Lives, Work, and World
- De: Jamie Metzl
- Narrado por: James Anderson Foster, Jamie Metzl
- Duración: 15 h y 44 m
- Versión completa
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Leading futurist and OneShared.World founder Jamie Metzl explores how genome sequencing, gene editing, artificial intelligence, and other technologies are not only changing our lives, but catalyzing each other in radical and accelerating ways. These technologies have the potential to improve our health, feed billions of people, supercharge our economies, and store essential information for millions of years, but can also—if we are not careful—do immeasurable harm.
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Great Book Somewhat Spoiled by Self-Promotion
- De Jack E. Koepke en 06-22-24
De: Jamie Metzl
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Biotech
- The Sorcerer's New Apprentice?
- De: Chuck Missler
- Narrado por: Chuck Missler
- Duración: 1 h y 41 m
- Versión completa
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Do the bright prospects of biotech justify tampering with mechanisms far from being understood? Will the biotech revolution cast a dark shadow over the first half of the 21st century as nuclear technology did over the last century? The astonishing advances in the field of microbiology now offer new remedies for many of mankind's most illusive and devastating diseases and even many genetic defects. However, these promises are not without a potential dark side.
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Informative, Inpirational & Personally Challenging
- De rdomke69 en 10-24-21
De: Chuck Missler
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The Breakthrough
- Immunotherapy and the Race to Cure Cancer
- De: Charles Graeber
- Narrado por: Will Collyer, Charles Graeber
- Duración: 7 h y 7 m
- Versión completa
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Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.
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Surprisingly gripping
- De Kari Niles en 01-21-19
De: Charles Graeber
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Moonshot
- Inside Pfizer's Nine-Month Race to Make the Impossible Possible
- De: Dr. Albert Bourla
- Narrado por: Stephen Graybill
- Duración: 6 h y 31 m
- Versión completa
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A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made “the impossible possible”—creating, testing, and manufacturing a safe and effective COVID-19 vaccine that previously would have taken years to develop. Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer overcame a series of crises that were compounded by social and political unrest.
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Incredible, consuming, history.
- De Mike Lake en 05-14-23
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Our Future Is Biotech
- A Plain English Guide to How a Tech Revolution is Changing Our Lives and Our Health for the Better
- De: Andrew Craig
- Narrado por: Andrew Craig
- Duración: 9 h y 44 m
- Versión completa
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The Apples, Amazons and Googles of the next few decades will be biotech companies. The tech companies of the last few years have changed how we do things but the businesses driving the biotech revolution are about making life better. These companies will solve many of our most intractable problems: cancer, dementia, diabetes, elderly care, mental health challenges, even power generation and agricultural production. The audiobook explains what biotech is, what is coming next, and in a final section, how interested investors can profit from it.
De: Andrew Craig
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The Drug Discovery and Development Cycle
- A Concise Overview of the Key Steps from Concept to Launch
- De: Kabir Hussain
- Narrado por: Rebecca Sharp
- Duración: 1 h y 31 m
- Versión completa
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The pharmaceutical drug discovery and development cycle is long and complex. This audiobook provides a concise overview of the whole process and offers insights into working in the pharmaceutical industry. It is ideal for individuals who are thinking about a career in this industry, as well as those who want to gain a general understanding of pharmaceutical drug discovery and development.
De: Kabir Hussain
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Bottle of Lies
- The Inside Story of the Generic Drug Boom
- De: Katherine Eban
- Narrado por: Katherine Eban
- Duración: 14 h y 26 m
- Versión completa
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From an award-winning Fortune reporter, an explosive narrative investigation of the generic drug boom that reveals the life-threatening dangers posed by globalization - The Jungle for pharmaceuticals.
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overbearing self-righteous indignation
- De VB en 01-13-20
De: Katherine Eban
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The Spare
- Biotech Billionaires, Book 1
- De: Ava Rani
- Narrado por: Vikas Adam, Sharmila Devar
- Duración: 9 h y 51 m
- Versión completa
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Sloan Amari has spent years in the shadow of her older brother Henry, heir apparent to their family’s company, Amari Global. Determined to show she’s been the right choice all along, she’s become a powerful corporate attorney and is on track to make history as the firm’s youngest senior partner. Now, the role of CEO at Amari Global may be within her grasp and Sloan’s eyes are on the prize.
De: Ava Rani
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The Code Breaker
- Jennifer Doudna, Gene Editing, and the Future of the Human Race
- De: Walter Isaacson
- Narrado por: Kathe Mazur, Walter Isaacson
- Duración: 16 h y 4 m
- Versión completa
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The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.
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Except for the author, this book is good!
- De Johan en 03-14-21
De: Walter Isaacson
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The Singularity Is Nearer
- When We Merge with AI
- De: Ray Kurzweil
- Narrado por: Adam Barr
- Duración: 10 h y 25 m
- Versión completa
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Since it was first published in 2005, Ray Kurzweil's The Singularity Is Near and its vision of the future have been influential in spawning a worldwide movement with millions of followers, hundreds of books, major films, and thousands of articles. During the succeeding decade, many of Kurzweil's predictions about technological advancements have been borne out, and their viability has become familiar to the public through such now commonplace concepts. In this entirely new book Ray Kurzweil brings a fresh perspective to advances in the singularity.
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victory lap
- De Anonymous User en 06-30-24
De: Ray Kurzweil
Lo que los oyentes dicen sobre From Breakthrough to Blockbuster
Calificaciones medias de los clientesReseñas - Selecciona las pestañas a continuación para cambiar el origen de las reseñas.
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- Momo Abbasi
- 04-28-24
Wonderful book!
If you want to understand the biotech industry you MUST READ this! Comprehensive and easy to follow.
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- Fox2
- 11-12-22
Excellent description of the biotech industry
Fantastic book describing the biotech industry from its beginning to now. Engaging and recommended to read or listen.
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- Anonymous User
- 09-12-23
Nothing to learn for pharma professionals
Nice introduction to the world of pharma R&D, but those who’ve been in the business have probably heard the stories many times already.
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