Dr. Nan Wise, a neuroscientist and sex therapist, discusses her journey into the field of neuroscience and the importance of understanding the brain in relation to sex and pleasure. She explains the different emotional circuits in the brain and how they impact our sexual experiences. Dr. Wise also talks about the importance of pleasure and the challenges women face in feeling safe and comfortable in their bodies. She emphasizes the need for comprehensive sex education and the role of parents in being sex educators. The conversation also touches on fMRI studies on orgasm and the power of the brain in experiencing pleasure. In this conversation, Nan Wise and Kristen Parise discuss the importance of exploring and understanding one's own body, the role of masturbation in sexual pleasure and communication with partners, the power of breathwork in promoting relaxation and pleasure, the concept of erotic fingerprints and different sexual styles, and the importance of balancing core emotions for a fulfilling sex life. Nan Wise also shares practical exercises for connecting with the body and enhancing pleasure.