#276 Understanding the chemistry of NVG-291’s efficacy for Rewiring SCI Recovery with Inventor Dr. Brad Lang

Brad Lang, PhD, is the neuroscientist and biotech inventor of the ISP drug, the basis of the NVG-291 trials which recently showed efficacy. His work has helped pave the way for one of the most promising new treatments for spinal cord injury in decades. Brad shares the story of how his early research led to the discovery of the intracellular sigma peptide (ISP), a molecule with the potential to unlock axon regeneration and repair damaged neural pathways. We explore the science behind ISP, the challenges of moving from lab discovery to human trials, and the role of persistence at big ideas (a mission imprinted on him by the late Dr. Jerry Silver) when the odds—and the nervous system—seem stacked against recovery. Along the way, Brad reflects on the emotional journey of being a scientist chasing a breakthrough, the worldwide attention on NervGen’s NVG-291, and the hope these advances bring not only to the SCI community but to the future of treatments for conditions once thought untreatable, and the potential reshaping of lives for those living years with SCI.

Resources https://nervgen.com/

Revisiting: Inside the NervGen NVG-291 Trial: Part I

Today we’re joined by Larry Williams, a participant in the NervGen Phase 1b/2a clinical trial for NVG‑291, an experimental therapy designed to promote nerve regeneration and restore function in people with spinal cord injuries. Larry takes us through his personal story—from the mountain biking accident that changed his life to the unexpected path that led him into one of the most closely watched clinical trials in the SCI community.

Larry opens up about the emotional and physical journey of recovery, the realities of rehabilitation, and what it meant to participate in a groundbreaking study. We talk about the power of scientific hope, the early but promising results from the chronic cohort of the NVG‑291 trial, and the value of being part of something bigger than oneself. Larry’s reflections offer a rare and candid window into life on the frontier of spinal cord injury research—and the enduring strength of the human spirit.

Resources https://nervgen.com/

Stay Connected: Subscribe, leave a review, and share this episode with anyone interested in advocacy for SCI funding!

BLINK of an Eye® Podcast is sponsored by BLINK of an Eye® Non-Profit:

A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel. Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

Blink of an Eye is sponsored by Baltimore Mediation:

To find out more about cutting edge conflict transformation skills courses to learn relational conflict theory and advocacy, mediation interventions and support for leaders and anyone navigating or facilitating difficult situations, conflict, or trauma, visit the website www.BaltimoreMediation.com and register for nationally certified 40 hour courses, including the Enneagram of personality for mediators to know themselves to stay neutral while offering opportunity for other’s empowerment.

To find out more about Louise visit: www.BlinkofanEye.org, www.BaltimoreMediation.com, www.BeingRelational.com

Season 4 Episode 19 - Dear Louise: A Conversation with Gabriel Rodreick

In a world where life's unpredictable twists and turns can sometimes bring us to our knees, one man's journey stands as a testament to the indomitable human spirit. Gabriel Rodreick, known to many as Freaque, found himself at a crossroads in 2008 when a Spinal Cord Injury accident, C5 complete, altered the course of his life, taking away his ability to walk and play the piano, passions that had defined his existence for years. In the face of this adversity, Gabriel discovered an incredible reservoir of strength and resilience by embracing the darkness he felt. He channeled his creativity into a new form of expression, forging a path forward with music production, giving birth to a genre he named "dirt folk." Inspired by artists like Kendrick Lamar and countless others, he allows the losses and darkness to shape a raw unvarnished invitation he extends to all participants in his music and music productions. Join Louise in an intimate conversation with Gabe beginning with his close brush with death, the experience of abandonment of friends, his overcoming his parents' terror of his venturing out into the world, to the many new normals, grappling with existential anxiety and ways he resources to stay grounded and emotionally balanced. Hear how he initiated "A Cripple's Dance," a remarkable project that brought together individuals with spinal cord injuries and able-bodied artists in awe-inspiring live music and dance performances. Through his work, he sends a powerful message to the world: "Darkness isn't as scary as we think."

To learn more about Gabriel:

https://gabrielrodreick.com/

Stay Connected: Subscribe, leave a review, and share this episode with anyone interested in advocacy for SCI funding!

BLINK of an Eye® Podcast is sponsored by BLINK of an Eye® Non-Profit:

A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel. Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

Blink of an Eye is sponsored by Baltimore Mediation:

To find out more about cutting edge conflict transformation skills courses to learn relational conflict theory and advocacy, mediation interventions and support for leaders and anyone navigating or facilitating difficult situations, conflict, or trauma, visit the website www.BaltimoreMediation.com and register for nationally certified 40 hour courses, including the Enneagram of personality for mediators to know themselves to stay neutral while offering opportunity for other’s empowerment.

To find out more about Louise visit: www.BlinkofanEye.org, www.BaltimoreMediation.com, www.BeingRelational.com

Season 4 Episode 14 - Dear Louise: A Conversation with WAGS of SCI

Elena Pauly and Brooke Pagé, both caregivers to partners with recent Spinal Cord Injuries, felt the deep isolation that comes with their role. Their connection on Instagram, fueled by their close proximity in Vancouver, became a lifeline. In November of that year, they birthed WAGS of SCI on Instagram, a community that not only hosted local caregiver events but also united "inter-abled" women - wives, partners, and girlfriends of those living with SCI. Together, they provide unwavering support for the unique challenges that come with loving someone with a spinal cord injury. Elena and Brooke tirelessly advocate and reach out, with long-term dreams of establishing a non-profit to support inter-abled relationships, boosting mental, emotional, and physical well-being awareness, and funding special trips for deserving couples.

Join Louise in an eye opening conversation with two very special advocates for those who are injured, but specifically for their caretakers and loved ones.

To learn more about WAGS and their work:

https://wagsofsci.com/

Stay Connected: Subscribe, leave a review, and share this episode with anyone interested in advocacy for SCI funding!

BLINK of an Eye® Podcast is sponsored by BLINK of an Eye® Non-Profit:

A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel. Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

Blink of an Eye is sponsored by Baltimore Mediation:

To find out more about cutting edge conflict transformation skills courses to learn relational conflict theory and advocacy, mediation interventions and support for leaders and anyone navigating or facilitating difficult situations, conflict, or trauma, visit the website www.BaltimoreMediation.com and register for nationally certified 40 hour courses, including the Enneagram of personality for mediators to know themselves to stay neutral while offering opportunity for other’s empowerment.

To find out more about Louise visit: www.BlinkofanEye.org, www.BaltimoreMediation.com, www.BeingRelational.com

Season 4 Episode 12 - Dear Louise: A Conversation with Matthew Rodreick

Matthew Rodreick serves as the Executive Director at United 2 Fight Paralysis, an organization at the forefront of the battle against paralysis. Through his leadership, he continues to amplify the voices of those impacted by SCI, pushing for groundbreaking research, fostering innovation, and advocating for comprehensive support systems. His journey, from caregiving to advocacy and leadership, showcases the remarkable impact of one individual's determination to make a difference in the lives of those affected by Spinal Cord Injury.

Join Louise in discovering the true meaning of perseverance, adapting to change, and the power of unconditional love.

To learn more about Matthew and his work:

https://u2fp.org/get-educated/curecast/all-episodes.html

https://u2fp.org/

https://www.instagram.com/roadreck/?hl=en

https://www.instagram.com/u2fp/?hl=en

Stay Connected: Subscribe, leave a review, and share this episode with anyone interested in advocacy for SCI funding!

BLINK of an Eye® Podcast is sponsored by BLINK of an Eye® Non-Profit:

A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel. Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

Blink of an Eye is sponsored by Baltimore Mediation:

To find out more about cutting edge conflict transformation skills courses to learn relational conflict theory and advocacy, mediation interventions and support for leaders and anyone navigating or facilitating difficult situations, conflict, or trauma, visit the website www.BaltimoreMediation.com and register for nationally certified 40 hour courses, including the Enneagram of personality for mediators to know themselves to stay neutral while offering opportunity for other’s empowerment.

To find out more about Louise visit: www.BlinkofanEye.org, www.BaltimoreMediation.com, www.BeingRelational.com

Season Finale: NerveGen with Meghan Morrow

Join Louise in this heartfelt finale of Season 4, where we dive into a journey exploring incredible medical innovations in spinal cord injury recovery. Meet Meghan Morrow, one of the driving forces along with Dr. Monica Perez in the groundbreaking NervGen trials at the Shirley Ryan Ability Lab in Chicago. From crafting affordable devices for stroke and brain injury patients to now leading exclusive trials with Dr. Perez, you'll hear Meghan's passion for innovation that is pushing the envelope for what is possible for those living with SCI 1-10 years from injury.

Stay Connected: Subscribe, leave a review, and share this episode with anyone interested in advocacy for SCI funding!

BLINK of an Eye® Podcast is sponsored by BLINK of an Eye® Non-Profit:

A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel. Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

Blink of an Eye is sponsored by Baltimore Mediation:

To find out more about cutting edge conflict transformation skills courses to learn relational conflict theory and advocacy, mediation interventions and support for leaders and anyone navigating or facilitating difficult situations, conflict, or trauma, visit the website www.BaltimoreMediation.com and register for nationally certified 40 hour courses, including the Enneagram of personality for mediators to know themselves to stay neutral while offering opportunity for other’s empowerment.

To find out more about Louise visit: www.BlinkofanEye.org, www.BaltimoreMediation.com, www.BeingRelational.com

Join us in this season finale, as we hear the inside scoop on these pivotal spinal cord injury trials, clarify who can qualify, and get a glimpse into cutting-edge developments which are transforming SCI rehabilitation medicine and what's next. Stay tuned for this touching finale filled with hope and progress, and get a sneak peak at a whole new Blink of an Eye experience coming in the new year in Season 5!

To learn more about Meghan Morrow

https://www.sralab.org/researchers/meghan-morrow-otrl

Canadian Paratriathlete Leanne Taylor

A biking accident left our next guest paralyzed from the waist down. However, instead of succumbing to despair, she made a bold decision while in the hospital – to become a paratriathlete. Just eight months after her injury, she completed her first paratriathlon, showcasing adaptability, resilience, and peak performance.

Leanne's story extends beyond sports; it's a journey through mental health challenges, finding hope, and building a fulfilling life. She champions body image and self-love, inspiring others to embrace their uniqueness. Leanne is also a staunch advocate for diversity and inclusion in the workplace, promoting equal opportunities for all. And she has a unique approach to how employers and employees together can make accommodations in the workplace.

Stay tuned.

To learn more about Leanne:

https://www.leanne-taylor.com/

Stay Connected: Subscribe, leave a review, and share this episode with anyone interested in advocacy for SCI funding!

BLINK of an Eye® Podcast is sponsored by BLINK of an Eye® Non-Profit:

A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel. Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

Blink of an Eye is sponsored by Baltimore Mediation:

To find out more about cutting edge conflict transformation skills courses to learn relational conflict theory and advocacy, mediation interventions and support for leaders and anyone navigating or facilitating difficult situations, conflict, or trauma, visit the website www.BaltimoreMediation.com and register for nationally certified 40 hour courses, including the Enneagram of personality for mediators to know themselves to stay neutral while offering opportunity for other’s empowerment.

To find out more about Louise visit: www.BlinkofanEye.org, www.BaltimoreMediation.com, www.BeingRelational.com

Season 4 Episode 18 - Trauma Healing Learning: Invaluable Wisdom and Integration with Amy Fox

In today’s episode, Amy Elizabeth Fox, the founder and CEO of Mobius Executive Leadership, offers a wealth of invaluable insights on why personal trauma healing is essential for leaders. With a rich background spanning senior leadership consultancy, public speaking, and empowering corporate leaders, Amy's journey is a source of key lessons in leadership communication, negotiation, and professional growth. Her extensive experience at healthcare startups, work with influential figures like Vice President Al Gore and Carl Sagan, and expertise in psychotherapy and emotional intelligence coaching make her a beacon of wisdom. As an alumna of Wesleyan University and earning a master's in Counseling Psychology, Amy's return to her passion for trauma healing invites all leaders to have a conversation with self to explore the role of their own journey of integration so they may experience wellbeing as they lead others wisely.

To learn more about Amy:

https://www.mobiusleadership.com/

Stay Connected: Subscribe, leave a review, and share this episode with anyone interested in advocacy for SCI funding!

BLINK of an Eye® Podcast is sponsored by BLINK of an Eye® Non-Profit:

A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel. Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

Blink of an Eye is sponsored by Baltimore Mediation:

To find out more about cutting edge conflict transformation skills courses to learn relational conflict theory and advocacy, mediation interventions and support for leaders and anyone navigating or facilitating difficult situations, conflict, or trauma, visit the website www.BaltimoreMediation.com and register for nationally certified 40 hour courses, including the Enneagram of personality for mediators to know themselves to stay neutral while offering opportunity for other’s empowerment.

To find out more about Louise visit: www.BlinkofanEye.org, www.BaltimoreMediation.com, www.BeingRelational.com