Dan began his multi-faceted career in New York where he moved from East Los Angeles at age twenty to pursue a career in musical theater. He performed off-Broadway, in regional theatre, summer stock and in musical revues at Manhattan’s most fabled cabarets including the Bon Soir in Greenwich Village. He later became a successful theatrical agent with clients in the original casts of countless Broadway musicals in the years from A Chorus Line to Cats, representing Tony Award winners and future Hollywood stars. He returned home to Los Angeles for an equally successful time as a casting director for stage and television before turning his talents to producing and directing.

Dan produced Lalo Guerrero: The Original Chicano, an award-winning documentary on his late father, Chicano music legend Lalo Guerrero. The film aired nationally on PBS stations in the Voces series hosted by Edward James Olmos and included a DVD/CD release. It continues to screen at national and international film festivals.

Dan is an influential activist, speaking out in print, television and radio interviews in English and Spanish on both Latino/Chicano and LGBTQ issues. He is a popular figure on the speaking circuit and has addressed many prestigious groups and organizations throughout the United States.

The Dan Guerrero Collection on Latino Entertainment and the Arts has been established in the California Ethnic and Multicultural Archives at the University of California at Santa Barbara (UCSB) and The Dan Guerrero Research Collection is housed at the UCLA Chicano Studies Research Center that includes his oral history recorded for their LGBT and Mujeres Initiative project. Most recently, the Dan Guerrero Gaytino collection became part of ONE National Gay and Lesbian Archives at the USC Libraries.