Episodios

  • Brand New Research on The Radical Benefits of Walking for Lowering Cholesterol, Body Fat, and Glucose, and Improving Your Mental Clarity with Gregg Mushen
    Oct 1 2025
    This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15. While the “10,000 steps a day” idea came from a marketing company in Japan, that doesn’t mean walking itself is a gimmick. Today’s guest shares why he is so passionate about walking and the research that supports this accessible habit, one that can be incorporated into most people’s lives and lead to significant results and shifts in their health and wellness journey. Today on The Dhru Purohit Show, Dhru sits down with Greg Mushen to explore the profound benefits of walking as a fundamental aspect of health and wellness. Greg shares how walking can be more effective than medications for managing blood sugar. He explains why maintaining a high step count supports weight loss and mood regulation, and highlights the critical role walking plays in cardiovascular health. He also emphasizes the importance of fiber and potassium in the diet, the influence of genetics on health, and the benefits of personal experimentation in achieving optimal outcomes. The conversation reveals why walking, one of the most low-cost and accessible habits, could be the missing link to better health and why you’ll want to hear the data for yourself. Greg Mushen is a health researcher, writer, and systems thinker with a long career in the tech industry. After years of building and scaling technology products, he turned his focus to one of medicine’s biggest puzzles: why subsistence populations largely avoid chronic disease. His approach combines anthropology with modern science, connecting lipid kinetics, gut microbiome ecology, and evolutionary biology into a systems-level understanding of human health. A lifelong builder, whether in startups, overland rigs, or new health frameworks, Greg now approaches human healthspan as the ultimate engineering problem: resilience, adaptability, and longevity. In this episode, Dhru and Greg dive into: The importance of doubling down on walking (1:10) Greg’s physical transformation through walking (9:31) Combining walking with resistance training (20:26) The link between lipid clearance, fat oxidation, and walking (26:25) Incorporating regular movement into daily life (27:45) Key comparisons between walking and running (34:08) Developing an elite VO₂ max (37:47) Vascular stiffening and endoPAT testing (41:47) Why fiber intake matters and how Greg increases intake (44:45) The role of genetics in cardiovascular health (58:43) The importance of potassium in the diet (1:08:15) Lessons from subsistence populations on chronic disease (1:14:02) Final thoughts and key takeaways (1:15:12) Also mentioned in this episode: Study on the Association of Daily Step Count and Step Intensity With Mortality Among US Adults Study on Postmeal Exercise Blunts Postprandial Glucose Excursions In People On Metformin Monotherapy Try This: 5 Things I Changed After Getting Genetic Testing Greg’s Chili Recipe For more on Greg, follow him on X/Twitter, Instagram, Threads, and Substack. This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15. Go to bioptimizers.com/dhru now and enter promo code DHRU to get 30% off any order of Magenesium Breakthrough and find out this month’s gift with purchase. Right now, get 20% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 h y 19 m
  • How Overeating Sugar Shrinks Your Brain & The Unexpected Thing That Grows It
    Sep 29 2025
    This episode is brought to you by Bon Charge and AquaTru. Dwindling memory is often seen as a normal part of aging. But just because it’s common doesn’t mean it’s normal. There’s a lot we can do to safeguard the memory center of our brain, and it’s never too late to start. Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Majid Fotuhi. He unpacks how excess sugar from a highly refined, processed diet can accelerate aging and damage key organs, including the kidneys, liver, and brain. Dr. Fotuhi also highlights animal studies linking sugar to brain decline, the blood markers we should all be monitoring, and practical strategies to support brain growth. Finally, he shares why having a strong sense of purpose is one of the most powerful ways to protect brain health. Dr. Fotuhi is a neurologist specializing in memory, concussion, and successful aging. With over 30 years of teaching, clinical practice, and neuroscience research at Harvard Medical School and Johns Hopkins, he has developed a multidisciplinary program to help people of all ages improve memory and attention. The results of his program have been published in numerous scientific journals as well as in his three books. Passionate about public education on brain health, Dr. Fotuhi also teaches in the Department of Psychological and Brain Sciences at George Washington University and at Harvard Medical School. In this episode, Dhru and Dr. Fotuhi dive into: Why sugar is so damaging to the brain (01:46) How elevated uric acid levels accelerate brain aging (11:22) Essential blood markers to monitor regularly (17:27) Key strategies to support brain growth (21:24) Why having a sense of purpose is vital for brain health (22:42) Final thoughts (30:35) Also mentioned: Full episode with Dr. Majid Fotuhi Try This: How Fructose Damages the Brain and Increases Our Risk for Alzheimer’s This episode is brought to you by Bon Charge and AquaTru. Right now, Bon Charge is offering my community 15% off. Just go to boncharge.com/DHRU and use code DHRU to save 15%. Aqua Tru is a countertop reverse osmosis purifier with a four-stage filtration system that removes 15x more contaminants than the bestselling water filters out there. Go to dhrupurohit.com/filter and get $100 off when you try AquaTru for yourself. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    30 m
  • The Mental Fitness Blueprint. How to Rewire Your Mind, Boost Confidence & Become Limitless with Maya Raichoora
    Sep 24 2025
    This episode is brought to you by Vuori, Bon Charge, Cozy Earth, and Ollie. When it comes to fitness, we don’t often think about training our brains. But today’s guest shows us that mental fitness is just as necessary. By rewiring our brains through repeated lessons, we can unlock our full potential and push past limitations. Today on The Dhru Purohit Show, Dhru sits down with Maya Raichoora to explore the power of the mind, our untapped capabilities, and how to rewire the brain to change the way we think, perform, and believe in what’s possible. Maya explains why what we repeat is often more influential than what is actually real. She also shares how to reframe doubt, practical techniques for visualizing the life we want, and why suppressing emotions can be harmful. Finally, she highlights how we can train our brains to focus on mental fitness and create lasting change. Maya Raichoora is a leading expert in mental fitness and visualization. She is the founder and CEO of Remap Mental Fitness and an award-winning entrepreneur. Maya has over a decade of experience and has made history as Nike’s first-ever mental fitness trainer. She has mastered the practice of visualization and is on a mission to make it accessible to all. A two-time TEDx speaker, her story and insight continue to inspire and educate audiences around the world. In this episode, Dhru and Maya dive into: Our brain doesn’t care what’s real, only what’s repeated (1:00) What holds people back from rewiring their brains (3:39) Why we should doubt our limitations instead of our potential (8:25) First steps to training the mind and building awareness (18:00) Maya’s personal story that led her to pursue her passion and profession (21:55) Five key techniques of visualization (33:09) Why suppressing emotions damages the mind, body, and life (43:53) How to build mental fitness (48:20) Habits and behaviors that shape our thinking and well-being (51:52) Building confidence and self-confidence (57:15) How to break free from the habit of complaining (58:48) Routines that helped Maya step into the power of the mind (1:08:13) How Maya recovered from her illness (1:10:28) The core message of Visualise (1:17:12) Red flags to watch for in dating (1:20:58) Final thoughts and takeaways (1:24:43) Also mentioned in this episode: Visualise Book For more on Maya, follow her on Instagram, Threads, LinkedIn, Apple Podcasts, Spotify, or visit her Website. This episode is brought to you by Vuori, Bon Charge, Cozy Earth and Ollie. Right now, Vuori is offering my listeners 20% off their FIRST purchase. Get yourself some of the most comfortable and versatile clothing on the planet at vuori.com/DHRU and discover the versatility of Vuori Clothing. Right now, Bon Charge is offering my community 15% off. Just go to boncharge.com/DHRU and use code DHRU to save 15%. Right now, get 40% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com, use the code DHRU, and you’ll get 60% off your first box of meals in your subscription. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 h y 30 m
  • The Most Underrated Tools for Longterm Weight Loss
    Sep 22 2025
    In the noisy debate over diets, calories, and weight loss, it can be hard to separate fact from hype. Today’s guest draws on deep expertise to cut through the noise, break down the science, and deliver trustworthy insights into nutrition and wellness. Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Layne Norton. Dr. Norton shares why exercise is critical for sustained weight loss and appetite regulation. He also explains that the decision to make lifestyle changes, along with consistency, is key to long-term success. Dr. Norton further discusses how the standard American lifestyle complicates weight loss and why it’s necessary to take an empathetic approach to helping people succeed. Dr. Layne Norton is a renowned fitness coach, bodybuilder, and entrepreneur known for his evidence-based approach to nutrition and training. He earned a Ph.D. in Nutritional Sciences from the University of Illinois and has achieved significant milestones as a competitive bodybuilder and powerlifter, including winning national titles and setting world records. Dr. Norton is also the founder of BioLayne LLC, a fitness and nutrition coaching company that has helped countless individuals achieve their health and fitness goals. He is also a prolific writer, speaker, and social media influencer, using his platforms to debunk fitness myths and promote science-based practices. In this episode, Dhru and Dr. Norton dive into: The importance of exercise for long-term weight loss (1:44) Exercise and appetite regulation (5:20) Stories of people who decided to change their lifestyle (16:11) The standard American lifestyle of convenience (23:41) Why some people struggle with appetite control and the role of Ozempic (33:02) Accountability and the need for an empathetic approach to weight loss (38:42) Final thoughts (42:29) Also mentioned: Full episode with Dr. Layne Norton This episode is brought to you by Maui Nui and Birch Living. Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now, but hurry, supply is limited! Get 25% off your Birch Living mattress during their extended Labor Day sale —just head to birchliving.com/dhru today! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    41 m
  • How To Catch Heart Disease, Alzheimer’s and Cancer Early: Tests You Need To Know About, Genetic Risk Factors, and Key Lifestyle Habits that Make a Difference with Dr. Eric Topol
    Sep 17 2025
    This episode is brought to you by One Skin and Momentous. Cardiovascular disease remains the leading cause of death worldwide. But today, we no longer have to wait for symptoms to understand our risk. Advances in technology now make it possible to get a clear snapshot of individual risk, not only for heart disease, but also for cancer and neurodegenerative conditions, empowering us to take proactive steps to lower risk and support long-term health. Our guest today breaks down what’s truly worth investing in and what we can skip. Today on The Dhru Purohit Show, Dhru sits down with Dr. Eric Topol, a cardiologist and Professor of Molecular Medicine at the Scripps Research Institute. Dr. Topol shares insights on the importance of preventive health, with a focus on cardiovascular disease, cancer, and neurodegenerative conditions. He explains the role of polygenic risk scores in assessing individual risk, explores the strengths and limitations of various testing methods, and highlights how lifestyle choices shape disease prevention. Dhru and Dr. Topol also discuss emerging technologies in health monitoring, the influence of environmental factors like air pollution, and what the future may hold for aging and health management. Dr. Eric Topol is Executive Vice President and Professor of Molecular Medicine at Scripps Research and founder of the Scripps Research Translational Institute. A practicing cardiologist and one of the ten most-cited researchers in medicine, he is renowned for his wor in AI, genomics, and digital clinical trials. Named to the Time 100 Health list in 2024, he also writes the Ground Truths newsletter and is the author of The Creative Destruction of Medicine, The Patient Will See You Now, Deep Medicine, and Super Agers. In this episode, Dhru and Dr. Topol dive into: Cardiovascular disease causes, risks, and prevention (1:07) Polygenic risk genetic links to disease and understanding your risk (7:56) Heart health with Dr. Topol’s key recommendations (13:21) Cancer testing types of tests and how to approach results (27:47) Medical guidance mistrust, confusion, incidental findings, and the importance of evidence-based practitioners (34:20) Alzheimer’s detection, blood work, testing, and the role of AI (43:13) Environmental risks, air pollution, and sleep irregularity, and why these factors must be addressed (53:20) Parkinson’s disease: the fastest-growing neurodegenerative condition (57:01) Prevention and lowering your risk of developing major diseases (59:52) Gut health and the gut-hormone connection (1:02:05) Aging and immunity: links between age-related diseases and the immune system (1:06:19) Measuring biological age (1:08:14) Final thoughts and takeaways (1:16:27) Also mentioned in this episode: Super Agers: An Evidence-Based Approach to Longevity Polygenic Risk Scores: Ready for Prime Time? What a Polygenic Risk Score Can and Can’t Tell You Allelica Polygenic Risk Test Dhru’s APOE Chat GPT Results For more on Dr. Topol, follow him on X/Twitter, The Scripps’ socials: X/Twitter, Facebook, Instagram, YouTube, TikTok, Threads, LinkedIn, Bluesky, or visit their Website. This episode is brought to you by One Skin and Momentous. Right now, One Skin is offering my community 15% off; just go to oneskin.co and use the coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Head to livemomentous.com and use code DHRU for 35% off your first subscription. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 h y 20 m
  • Is Sauna Use One of the Most Underrated Tools We Have for Reducing Risk of All-Cause Mortality? This Expert Says Yes.
    Sep 15 2025
    This episode is brought to you by Branch Basics and Bon Charge. What if you could lower your risk of cardiovascular disease by 69%? Today’s guest reveals how regular sauna usage, one of the most underrated tools for longevity, brain health, and cardiovascular function, can make that possible. Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Susanna Søberg on the benefits of consistent sauna use. Dr. Søberg highlights the added impact of pairing sauna with exercise, offers practical tips for adapting to the heat, and shares the latest research showing how sauna use can reduce all-cause mortality and boost nitric oxide production. Dr. Susanna Søberg is one of the world’s leading researchers and experts in cold and heat therapy, as well as functional breathing. She is the founder of the Soeberg Institute, which offers an online, research-backed curriculum designed to help people optimize stress management and performance for a healthier, happier life. Dr. Søberg earned her PhD in metabolism at the University of Copenhagen, where her research advanced our understanding of brown fat metabolism in adults. In this episode, Dhru and Dr. Søberg dive into: The health benefits of regular sauna use (1:27) Pairing sauna with exercise for an extra boost (3:20) How to adapt to heat in the sauna (8:15) Research on sauna use and reducing all-cause mortality (12:37) How the brain responds to sauna (15:34) Sauna and nitric oxide production (18:29) Also mentioned: Full episode with Dr. Susanna Søberg Try This: 2 Fascinating Studies, Sauna Benefits, a Way to Beat Jet Lag, and More Try This: Sauna Bathing for Longevity, Cognition, & Heart Health This episode is brought to you by Branch Basics and Bon Charge. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics! Right now, Bon Charge is offering my community 15% off; just go to boncharge.com/DHRU and use the coupon code DHRU to save 15%. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    21 m
  • Simple and Safe Evidence-Based Ways to Reduce Autism Risk From a Physician and a Father On a Mission
    Sep 10 2025
    This episode is brought to you by BiOptimizers, Birch Living, and Our Place. Autism rates have increased fivefold over the past twenty years. While much remains unknown about how children develop autism, research suggests that the rise in cases may not be explained by increased diagnoses alone. Today’s guest takes us on a deep dive into autism and shares his proposals for reducing these rates. Today on The Dhru Purohit Show, Dhru sits down with Dr. Jeff Zadeh for a deep dive into autism and the research he’s uncovered on key strategies that may reduce the likelihood of a child being diagnosed with autism. While Dr. Jeff acknowledges that much remains unknown about why some children are on the autism spectrum, he highlights the top nutrients and vitamins women should focus on before pregnancy to help lower the risk. From dosages to deficiencies, Dr. Jeff breaks down what the research shows so far. He also shares his personal journey with his son’s diagnosis and what inspired him to begin exploring this topic in depth. Dr. Jeff Zadeh, a board-certified internist with nearly 30 years of experience, founded Dallas Medical Specialists in 2005 and later moved his practice to rural North Texas, where he serves as a hospitalist, trauma director, and emergency physician. After his oldest son was diagnosed with autism, he discovered research suggesting many cases may be preventable through prenatal counseling, yet most physicians were unaware of it. Inspired by this and the work of Dr. David Berger, he wrote Autism Prevention 5 Days a Week to share simple, evidence-based prevention strategies in accessible language. In this episode, Dhru and Dr. Zadeh dive into: Dr. Zadeh’s personal journey with his son’s autism diagnosis (00:55) Dr. Zadeh’s medical background and the challenges of obtaining a diagnosis (8:50) The importance of supplementation before conception (27:32) What to look for in prenatal vitamins (45:27) The 5-day-a-week proposal and the studies behind it (49:55) Maintaining sufficient iron levels in women (1:06:33) Why checking thyroid levels before pregnancy is essential (1:15:21) Environmental toxin exposures affecting pregnancy (1:15:26) The risks of taking Tylenol during pregnancy (1:27:23) The connection between celiac disease and autism (1:31:35) How increasing DHA omega-3 and vitamin D intake may lower the risk of autism (1:35:32) The role of choline in autism prevention (1:51:12) Key factors we should pay attention to (1:54:47) Dr. Zadeh’s reflections as a parent of a child on the autism spectrum (2:00:20) Final thoughts and takeaways (2:07:30) Also mentioned in this episode: Dr. Jeff Zadeh’s Slides Autism Prevention 5 Days a Week Dr. Rhonda Patrick BPA Instagram Post For more on Dr. Zadeh, follow him on X/Twitter and visit his Website. This episode is brought to you by BiOptimizers, Birch Living, and Our Place. Upgrade your digestion with enzymes! Go to bioptimizers.com/dhru now and enter promo code DHRU to get 15% off any order and free gifts for a limited time. Get 25% off your Birch Living mattress during their Labor Day Extended Sale—just head to birchliving.com/dhru today! Reduce your toxic load by upgrading your cookware! Go to fromourplace.com today and use promo code DHRU at checkout to receive 10% off any order. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    2 h y 11 m
  • 70% of Homes In the U.S. Have Mold. Here's How to Protect Your Health and Your Home from Toxic Mold
    Sep 8 2025
    This episode is brought to you by Pique Life and Branch Basics. Air quality and mold are major factors in overall health and wellness. In fact, 70% of homes in the United States contain at least one species of mold. Exposure can trigger chronic inflammation, fatigue, and brain fog, but with the right knowledge, you can take proactive steps to protect your health. Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Michael Rubino to explore how and why mold is so prevalent in most homes and how it can worsen autoimmune disease. Michael breaks down the most common sources of mold people encounter and why the problem is getting worse. He also highlights the four most toxic types of mold and explains how their presence in the body can cause damage through self-preservation mechanisms. Finally, Michael explains why some people are more susceptible to the effects of mold than others. Michael Rubino is the Founder of HomeCleanse, President of the Change the Air Foundation, and host of the Never Been Sicker podcast. A council-certified Mold Remediator with a background in construction, he focuses on helping immunocompromised individuals recover from mold exposure. In this episode, Dhru and Michael dive into: Why mold is the number one toxin found in homes (1:56) The most common sources of mold people encounter (6:11) Why the mold problem is getting worse (7:28) Memorable client stories (13:22) Types of mold to watch out for (18:32) The four most toxic molds (20:08) How mold damages the body through self-preservation mechanisms (24:01) Why some people are more affected by mold than others (26:08) Final thoughts (28:03) Also mentioned: Full episode with Michael Rubino This episode is brought to you by Pique Life and Branch Basics. Right now, Pique Life is offering 20% off their Sun Goddess Matcha. Plus, you’ll get a free beaker and frother when you go to piquelife.com/dhru. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    28 m