In this podcast episode, Paul Limburg, MD, MPH, discusses the movement from academics to industry, developments in colorectal cancer screening tools and more.

• Intro 1:11
• Paul Limburg, MD, MPH 1:17
• How did your early influences and childhood years lead you to become interested in gastroenterology and the career you have today? 1:34
• Who were your early inspirations? 2:14
• How did you transition from a career in academics and sciences to a life on the commercial side? 3:34
• How did your role at Exact Sciences come about? 5:58
• Was it a hard decision to take a new position? 7:47
• Chey and Limburg on the joy of advancing science and innovation. 9:03
• Were there any cultural differences that shocked you about the ways work is done in your previous and current positions? 10:10
• Do you see Exact outsourcing scientific research as the company grows? 12:12
• What does a typical day look like for you at Exact? […] What are you responsible of as the leading physician? 13:28
• From a product standpoint, what is ahead on the roadmap for Exact Sciences? […] What are you most excited about regarding next-generation multi-target stool testing and its impact? 15:14
• How do you respond to gastroenterologists' skepticism and concerns surrounding stool-based screening? 21:15
• What about addressing the concerns surrounding how we can ensure patients with a positive FIT test go in for a colonoscopy? 23:22
• How much of an issue are language barriers when it comes to screening tools? 28:11
• Can you talk about how Exact Sciences are using AI and the evolution of the microbiome internally or in product development? 29:42
• Do you see a future for stool-based testing in between/in combination with colonoscopies? 32:59
• Have you noticed differences in sensitivity and specificity based on age? 34:07
• What are your thoughts on making these tools available in a direct-to-consumer offering? […] How do you make these screening tools more readily available while weighing the usage risks? 35:08
• What is the rate of patients who have a positive stool-based test getting a colonoscopy? 38:44
• If you were talking to a GI fellow deciding to make the jump to industry, what do you tell them? 41:58
• Thank you, Paul 44:55
• Thanks for listening 45:21

Paul J. Limburg, MD, MPH, is chief medical officer for screening at Exact Sciences and emeritus professor of Medicine at Mayo Clinic.

We'd love to hear from you! Send your comments/questions to guttalkpodcast@healio.com. Follow us on X @HealioGastro @sameerkberry @umfoodoc. For more from Dr. Limburg, follow @limburg_paul and @ExactSciences on X.

Disclosures: Chey and Berry report no relevant financial disclosures. Limburg reports he is an employee of Exact Sciences.

In this podcast episode, Amy Oxentenko, MD, discusses her initiatives as ACG president, addressing workforce challenges in the GI space and more.

• Intro :50
• Amy Oxentenko, MD 1:09
• How does it feel to be finishing your year as ACG president? 1:54
• What were your main initiatives and goals for this year, and how did they go? 3:28
• Is there a teaser you can give us for what you will reveal at the ACG annual meeting? 8:39
• Chey and Oxentenko on the critical role of additional research within the future of gastroenterology. 12:01
• What research has the college conducted to better understand the true clinical FTE available to patients? […] Are there certain solutions that have stood out to you in your work? 13:19
• Will there be a task force to comment on the rise of clinicians choosing to participate in more of a locum tenens practice? 18:35
• Can you speak about the recent progress made toward addressing the gender gap in GI? 21:32
• What can listeners do in this political climate to continue to make strides towards equity in the field? 25:47
• What have you learned about yourself in the past year as ACG president? 30:09
• What are you optimistic about in GI after this year? 33:19
• On the other hand, what are you most concerned about for gastroenterology? 36:17
• Any advice for the next ACG president? 39:31
• What is next for you? 41:18
• Thank you, Amy 43:10
• Thanks for listening 43:52

Amy Oxentenko, MD, FACP, FACG, AGAF, is a professor of medicine and vice dean of Mayo Clinic Practice. She is a member of the ACG board of trustees and executive team, serving as ACG president from October 2024-October 2025.

We'd love to hear from you! Send your comments/questions to guttalkpodcast@healio.com. Follow us on X @HealioGastro @sameerkberry @umfoodoc. For more from Dr. Oxentenko, follow @AmyOxentenkoMD on X.

Disclosures: Chey, Berry and Oxentenko report no relevant financial disclosures.

In this special crossover podcast episode, Tuesday Night IBS hosts Jeffrey Roberts, MSEd, BSc, Erica Dermer and Kate Scarlata, MPH, RDN, are joined live by William Chey, MD, and Amanda Lynett, MS, RDN, at FOOD the Main Course Conference in Ann Arbor, MI.

• Intro :02
• About Scarlata :30
• About Chey 1:07
• About Lynett 1:49
• Chey, what are your goals for this year's FOOD the Main Course Conference? 2:58
• How do you feel that mechanisms of diet are affecting microbiomes? 5:37
• Amanda, what have you learned over the years as you have put together this conference, and how do you think this experience has shaped a more well-rounded program for clinicians? 8:23
• What are you personally going to take away from the conference this year? 11:17
• A discussion on peer-to-peer interactions, the spirit of collaborative care, and what each provider is bringing to the table. 12:22
• Kate, tell us about why you come back to this conference every year. 17:32
• What challenges did you overcome to move the needle forward in diet and GI conditions? 19:14
• Chey, can you talk about the correlation between stress and diet when it comes to IBS? 24:21
• How are we dealing with the ramifications of GLP-1s? 29:33
• As providers, what is your first instinct when patients tell you they started GLP-1s? 32:28
• How is the community going to help listeners weed through Internet noise to find accurate information? 35:01
• Group discussion on the rise of severe constipation. 41:31
• Who decides to send patients for colectomy consultations? 43:33
• Is there anything else you want to share or highlight from the conference? 47:25
• Thank you all 48:58
• Thanks for listening 49:42

Erica Dermer is an IBS and Celiac Disease patient who hosts the Celiac and the Beast blog and You Had Me at Eat podcast series.

Amanda Lynett MS, RDN, is a registered dietitian with her masters. Amanda is with the Division of Gastroenterology at Michigan Medical in Ann Arbor.

Jeffrey Roberts, MSEd, BSc, is a patient advocate and creator of the first website for IBS sufferers. He is the co-founder of Tuesday Night IBS.

Kate Scarlata, MPH, RDN, is a US-based dietitian with over 30 years of experience. Kate's expertise is in gastrointestinal disorders and food intolerance.

We'd love to hear from you! Send your comments/questions to guttalkpodcast@healio.com. Follow us on X @HealioGastro @sameerkberry @umfoodoc. For more Tuesday Night IBS, be sure check out TuesdayNightIBS.com and to follow and subscribe to their podcast.

Disclosures: Chey and Roberts report no relevant financial disclosures. Scarlata reports stock options with Epicured LLC and FODY Food Company, financial support from Dr. Schar, Mahana Therapeutics, Nestle Health Science, Olipop, Pendulum, QOL Medical.