Join us as we zoom into the "nano world" with Kelso Arthur, a third-year PhD student in Environmental and Molecular Toxicology at Oregon State University. In this episode we discuss nano and microplastic use in agricultural pesticides, what impacts they could have on environmental health, and how indicator species can help us assess their effects. Kelso shares their journey on how their roots in Kentucky helped pave their pathway into graduate school. Hosted by Matthew Vaughan and Esteban 'E' Hernandez.

Mammals encompass some of the most interesting animals on the planet. We can see how bats have mastered the sky with wings like birds or how dolphins have adapted streamlined bodies for life in the ocean just like fish. The ability to evolve similar characteristics to overcome common problems found in the environment is called convergent evolution and opens our eyes to the fundamentals of how life has changed to face the challenges of our planet. One such trait that is the product of convergent evolution is echolocation, which is the subject of research for our guest on the show this week Serena Frazee.

If you walk into any grocery store today and find yourself in the beverage aisle, you’ll be able to find all sorts of “prebiotic” sodas touting ingredients like inulin that claim to improve gut health. Many of us are familiar with probiotics and the gut benefits of fermented or cultured foods that contain beneficial bacteria, but prebiotics are a little different. Prebiotics are typically nondigestible fiber compounds that pass undigested through the upper part of the gastrointestinal tract and function as a food source for your gut’s microorganisms.

However, it is unclear what the effects of prebiotics are on the human gut microbiome, and more specifically, how diet influences these effects. This is exactly what Emilee Lance, second year PhD student in the department of microbiology, is aiming to understand. Under the guidance of PIs Ryan Mueller and Tom Sharpton, Emilee is working on understanding how the gut microbiome is affected by prebiotics like inulin, and the impact that diet can have on prebiotic efficacy. Using a gut simulator called a SHIME (The Simulator of the Human Intestinal Microbial Ecosystem) she is able to totally control the initial microbial environment, diet, and mimic specific regions of the gastrointestinal tract such as the stomach, small intestine and different colon regions.

Sometimes the smallest things in the universe can answer some of the largest questions. That seems to be the case with neutrinos. But what exactly are these fundamental particles, that also happen to be the most abundant in the universe, and why are they of importance? Listen in to hear Noah shed light on all things neutrinos, including undereground research facilities! Hosted by Matthew Vaughan and Taylor Azizeh.

Join us as we dive into the world of apex predators with shark researcher Jessica Schulte, a PhD candidate studying the foraging behavior and movement of broadnose sevengill sharks in the Pacific Northwest. This episode is packed with mystery, fun shark facts, unexpected diet discoveries, crazy field stories, and inspiring ventures that lead to a career working with sharks! Hosted by Matthew Vaughan and Taylor Azizeh.

For most of the time that biochemists have been studying proteins they have preached the widely adopted dogma that structure equals function. Proteins are macromolecules made of chains of amino acids, and as they are produced they fold into intricate and specific shapes. These shapes or ‘structures’ are critical to the tasks that they perform, like producing energy for the cell, carrying molecular cargo from one end of the cell to the other, or letting ions across the cell membrane. However, over 30% of the protein humans produce has no specific structure. These are called intrinsically disordered proteins, and only in the last 15 years have they been brought into the spotlight of biochemistry and biophysics research (Structural Disorder in Eukaryotes).
Hannah Stuwe is a fourth-year PhD candidate in Biochemistry and Biophysics, and her research revolves around disordered proteins, particularly a protein from SARS-CoV-2 called the nucleocapsid protein. In her work she uses state-of-the-art techniques specifically suited for studying disordered proteins to understand how the flexibility of this protein changes throughout the viral replication cycle.

Per- or Polyfluoroalkyl substances (PFAS) are a class of chemicals that are known for their ability to contaminate our environment and be resistant to breaking down. However, there’s still a lot to learn about their potential for toxicity. One way scientists can better understand PFAS toxicity is by using the embryonic zebrafish models. These tiny fish have a genome that is around 70% similar to humans. This makes the zebrafish a powerful tool in understanding how some chemicals may express toxicity in humans. Eli Cowan is a second-year PhD student in the lab of Robyn Tanguay, which is a part of the Environmental and Molecular Toxicology lab here at OSU. His research focuses on using the zebrafish model to understand how PFAS exposure may lead to adverse effects in development. With this data and using his in-dept knowledge of biology, Eli then can help answer questions about how PFAS may be toxic to people. Eli was raised in Vicksburg, Mississippi, where he first encountered zebrafish toxicology in a locally-based lab. Eli has always been a natural born scientist, and that curiosity has led him all the way across the country pushing the bounds of science.