Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker.

While everyone tries to unpick the new NHS 10 year plan, we focus on the here and now with three new pieces of research.

We kick off with two gems in the BJGP - first, examining whether anti-depressants actually help with insomnia, and second, whether anti-depressants cause postural hypotension in older people and which may be the worst. Finally, we look at a good news story, with data publishing on a new treatment for cancers linked to mismatch repair genes.

References

BJGP Insomnia paper

BJGP Anti-Ds and postural hypotension paper

NEJM dMMR gene cancer therapy

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Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. In this episode, we look at three new pieces of research with implications for general practice.

Firstly, can exercise prevent the recurrence of colorectal cancer? Short answer, yes. But how much exercise did you need to do, and what on earth is a MET?

Secondly, what are the concerns around low-dose amitriptyline use for IBS from patients and GPs? How can we aid the discussion?

Finally, can SLGT2 inhibitors improve liver disease? Is this the new treatment for our patients with MASLD (the condition formerly known as NAFLD?

References

NEJM Exercise and CRC

METs Wikipedia

BJGP IBS & amitriptyline prescribing

BMJ SGLT2i & MASLD

NB Blog MASLD: The rebrand you never heard of

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Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. In this edition, we look at three new pieces of research.

First, in the BMJ, a paper exploring whether a GP-led psychological intervention can help PTSD symptoms in our patients after ICU. Could this also be successful for other forms of trauma?

Second, in the Lancet, research looking at whether semaglutide can improve walking distance in patients with diabetes and intermittent claudication.

Finally, in the BJGP, can a practice-led physical activity intervention improve symptoms in survivors of cancer? Will anyone actually want to do it? The answer, and who, may surprise you.

References

Poor by Katriona O'Sullivan

BMJ PTSD paper

Lancet GLP1ra and PAD

BJGP Physical activity and cancer survivors

Moving Medicine

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Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. In this episode, we are joined by Dr Stephen Bradley, lead author of a new paper published in the BJGP looking at rates of CXR use in general practice and how this influences lung cancer stage at diagnosis and mortality.

He discusses the findings of his research and how this might influence our practice.

In other research, we look at a new paper in the BMJ on orthostatic HYPERtension - yes, you read that correctly - does treatment help, and does it really matter in the first place? And from the Lancet, research looking at the role of urodynamic studies in women with refractory overactive bladder - does it improve outcomes, or should it be stopped?

References

BMJ Orthostatic hypertension and BP treatment

BMJ OH editorial

Lancet Refractory overactive bladder & urodynamic studies

BJGP CXR in GP & lung cancer staging and mortality

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Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. In this episode, we look at three new papers with practice-changing consequences.

Firstly, can treating partners of women with bacterial vaginosis prevent recurrence? Secondly, can semaglutide be effective in alcohol misuse? Finally, is tirzepatide an effective treatment for pre-diabetes in people with obesity (take a guess...!)?

References

NEJM Male partner treatment for BV

JAMA Psychiatry GLP1a & alcohol

NEJM Tirzepatide for Pre-diabetes

www.nbmedical.com/podcast

Welcome to the Hot Topics podcast with Dr Neal Tucker. This is the fourth in our series of special podcasts where we talk to interesting and influential people from the world of general practice.

In this interview, we talk to Dr Helen Salisbury, GP & BMJ columnist.

A working GP for more than 20 years, Helen has also reached the wider medical community through her regular column in the BMJ. A fierce advocate for general practice, we talk about her career, how general practice has changed over the past 20 years, what writing for the BMJ involves, her work with the BMA and vision for general practice in the future.

www.nbmedical.com/podcast

Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. This week we look at three new pieces of research.

First, we have a paper in the BMJ exploring arterial thrombosis risk with modern hormonal contraceptives including newer treatments such as the combined patch and ring. Second, we have a BJGP paper looking at which type of safety net advice is the most effective. Finally, a new paper in JAMA Internal Medicine collates trials on anti-virals for influenza. Can any of them provide genuine benefit?

And don't forget our NB Plus offer - £25 discount on an annual subscription until the 17th of February.

Resources

BMJ

BJGP

JAMA

Healthier Together patient info

www.nbmedical.com/podcast

Welcome to the Hot Topics podcast with Dr Neal Tucker. This is the third in our series of special podcasts where we talk to interesting and influential people from the world of general practice.

In this interview, we talk to Dr Euan Lawson, GP and editor of the BJGP.

The journal will be familiar to all clinicians in general practice and has gone from strength to strength over the past few years. We talk about his career and how he became editor, discuss the world of research including the most influential papers published during his tenure, consider the importance of inclusion health in the changing face of GP, and discuss his vision for the future.

And remember our recent NB Clinic in Inclusion Health can be watched on demand here.

www.nbmedical.com/podcast