Per- and polyfluoroalkyl substances, a class of chemicals known as PFAS, are often called “forever chemicals” because of how long they persist in the environment. They are prevalent in drinking water and have been linked to negative health outcomes.

A slew of cleantech start-ups are cropping up with the aim of breaking down and destroying PFAS molecules. In this episode of C&EN Uncovered, reporter Britt Erickson explores the technologies behind these companies and the competition among them.

C&EN Uncovered, a project from C&EN’s podcast, Stereo Chemistry, offers a deeper look at subjects from recent stories. Check out Britt’s cover story on the destruction techniques for these “forever chemicals” at cenm.ag/foreverchemicals.

Cover photo: Argon gas plasma, which can break down PFAS, on the surface of liquid water

Subscribe to Stereo Chemistry now on Apple Podcasts, Spotify, or wherever you listen to podcasts.

A transcript of this episode is available now at cen.acs.org.

Credits

Executive producer: Gina Vitale

C&EN Uncovered host: Craig Bettenhausen

Reporter: Britt Erickson

Audio editor: Ted Woods

Copyeditor: Bran Vickers

Story editor: Michael McCoy

Episode artwork: Courtesy of Selma Mededovic Thagard/Clarkson University

Music: “Hot Chocolate,” by Aves

Contact Stereo Chemistry: Contact us on social media at @cenmag or email cenfeedback@acs.org.

As the science of drug discovery has grown in scale and gotten more complicated, so have the drug molecules themselves. But there’s a promising class of drugs made of just a handful of atoms that punch above their weight by leveraging the natural chemistry of the cell.

Recent discoveries have opened up a new era of pharmaceutical chemistry that some people are calling a golden age. In this episode of C&EN Uncovered, reporter Laura Howes explains this exciting field of research and its implications for the drugs of the future.

C&EN Uncovered, a project from C&EN’s podcast, Stereo Chemistry, offers a deeper look at subjects from recent stories. Check out Laura’s cover story on small-molecule drugs at cenm.ag/smallmol.

Subscribe to Stereo Chemistry now on Apple Podcasts, Spotify, or wherever you listen to podcasts.

A transcript of this episode is available at cenm.ag/smallmolpod.

Credits

Executive producer: Gina Vitale

C&EN Uncovered host: Craig Bettenhausen

Reporter: Laura Howes

Audio editor: Brian Gutierrez

Copyeditor: Bran Vickers

Story editor: Mitch Jacoby

Episode artwork: Chris Gash

Music: “Hot Chocolate,” by Aves

Contact Stereo Chemistry: Contact us on social media at @cenmag or email cenfeedback@acs.org.

Resting on the bottom of the ocean are potato-sized nodules of valuable minerals that are more or less up for grabs. Multiple corporations and some nations are racing to build deep-sea drones that can withstand the extreme conditions at the seafloor and bring these 1-20 cm nodules to eager buyers on the surface.

Many of the metals in these nodules are critical for green technologies like batteries. But these nodules are also an important part of ecosystems we are just beginning to understand. In this episode, C&EN reporter Priyanka Runwal chats with host Craig Bettenhausen about this complex issue.

C&EN Uncovered, a project from C&EN’s podcast, Stereo Chemistry, offers a deeper look at subjects from recent stories. Check out Runwal’s full story at cenm.ag/seafloormine.

For more about mining the oceans, check out this episode of Stereo Chemistry from earlier this year about filtering minerals directly out of the water: cenm.ag/ocean 

Subscribe to Stereo Chemistry now on Apple Podcasts, Spotify, or wherever you listen to podcasts. 

A transcript of this episode is available at cenm.ag/deapsea.

Credits

Executive producer: Gina Vitale

C&EN Uncovered host: Craig Bettenhausen

Reporter: Priyanka Runwal

Audio editor: Brian Gutierrez

Copyeditor: Bran Vickers

Story editor: Laura Howes

Episode artwork: Diva Amon/Craig Smith/University of Hawaii

Music: “Hot Chocolate,” by Aves

Contact Stereo Chemistry: Contact us on social media at @cenmag or email cenfeedback@acs.org.