Episodios

  • Antiplatelets - Protease activated receptor 1 antagonists and a Miscellaneous class.
    Aug 15 2023

    We are at the end of the road of our anti-platelet pathway exploration!!!! We look at 2 different ways of inhibiting the platelets from forming a clot and the different patient populations that these drugs are used. Hooray to the anti-platelets though I'm sure this isn't the end there must be another novel/cutting edge therapy just around the corner that a scientist/discoverer is just about to unveil......

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    15 m
  • Antiplatelets - Glycoprotein Platelet Inhibitors
    Jul 20 2023

    In today's episode I give a gigantic high five to our scientists/discoveres! Figuring out yet another way to stop clot formation by working out the puzzle of how platelets work to form a clot. With that worked out they then make drugs that put a stop 🛑 to this and voila.... no clots are formed.

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    15 m
  • Antiplatelets - Thienopyridines
    Jul 7 2023

    What a lovely name to pronounce Thienopyridines! Another nugget as to how platelets work to cause clots to form and how this class stops that from happening. Very Sci-Fi how these platelets work.

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    16 m
  • Antiplatelets - Platelet Aggregation Inhibitors.
    Jun 30 2023

    In the year 1899 (others say 1897) Asprin was marketed by Bayer Pharmaceuticals. Yep and we still use it today talk of super drug. It's used and indicated in many areas but again tunnel vision in this episode where we are specifically interested in how are clots not formed when asprin is around.

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    13 m
  • Anticoagulants - Direct Thrombin Inhibitors (DTIs)
    May 29 2023
    It's a wrap with the anticoagulants! The DTIs some interesting fun facts especially the one that has to do with Leeches 😊! They came into the market in the 2000s and have been very helpful on this anti-coagulation journey. --- Support this podcast: https://podcasters.spotify.com/pod/show/wambui-wamburu/support
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    12 m
  • Anticoagulants - Factor 10a Inhibitors
    May 23 2023
    Our amazing discoverers/scientists are always at work and in the years of 2000s they gave us this class. The other oral anticoagulants besides Warfarin. Factor 10a inhibitors part of the coagulation cascade a genius way to stop that clot. --- Support this podcast: https://podcasters.spotify.com/pod/show/wambui-wamburu/support
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    10 m
  • Anticoagulants- Heparins.
    May 8 2023
    We continue with our oldies but goodies. Heparin was first discovered in 1916!!! Ofcourse we have improved on it since then but they all basically work the same way. Still a huge part of our treatment protocols. --- Support this podcast: https://podcasters.spotify.com/pod/show/wambui-wamburu/support
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    13 m
  • Anticoagulants - Warfarin
    Apr 25 2023

    Warfarin is over 60 YEARS OLD yet it's the most prescribed oral anticoagulant. Listen up, refresh yourself on this oldie but really a good goodie.

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    16 m