Bairey Merz discusses the latest directions in microvascular and endothelial research, including links to heart failure with preserved ejection fraction, integration of adverse pregnancy outcomes and autoimmune disease into models, and promising technological advances.

Timestamps:

00:53 – Directions of the WISE programme

01:47 – Preserved ejection fraction

04:51 – Adverse outcomes of microvascular disease

08:42 – Technology improving outcomes

This episode examines how diagnostic tools and imaging for microvascular dysfunction are evolving, the paradox of 'clear' arteries in symptomatic women, and barriers to broader implementation in clinical practice.

Timestamps:

00:45 – Angina in women

03:43 – Defining ischaemia

05:35 – Barriers to microvascular testing

Bairey Merz explores the science of microvascular dysfunction in women, the role of the WISE initiative, and how these findings have redefined diagnosis, preventive cardiology, and symptom assessment.

Timestamps:

01:04 – Barbra Streisand Women's Heart Center

03:35 – WISE initiative

06:36 – Microvascular angina

11:11 – Preventative cardiology

Noel Bairey Merz answers rapid-fire questions on women's heart health, including misconceptions about angina, key insights from the WISE study, and emerging imaging technologies.

In the final episode, Vidur Mahajan looks ahead to the future of radiology. From AI-enabled education to convergence with genomics and pathology, this discussion explores how imaging and AI will reshape diagnostics over the next decade.

Timestamps:
00:00 – Introduction

00:51 – Exciting innovations

03:47 – Role of radiologists

05:59 – AI and education

08:40 – AI and genomics

10:55 – What's next?

What does it take to deploy AI across national health systems? In Part 2, Vidur Mahajan shares lessons from large-scale rollouts at RadNet and Singapore's health network, covering interoperability, regulation, and success metrics.

Timestamps:
00:00 – Introduction

00:55 – Deploying CARPL

05:50 – Real-world stories

10:52 – Regulatory challenges

13:30 – Interoperability

16:17 – Success metrics

In this episode of Hema Now, we take a deep dive into myeloproliferative neoplasms (MPN), with a particular focus on myelofibrosis, one of the most complex and challenging MPNs to manage. Ciro Rinaldi discusses what distinguishes myelofibrosis from other chronic MPNs, the biological drivers of disease progression, and the critical role of inflammation and the bone marrow microenvironment. The conversation also explores emerging combination therapies, translational research hurdles, and how the management of myelofibrosis may evolve over the next decade.

Timestamps: 

00:00 – Introduction

00:59 – Myeloproliferative neoplasms

04:00 – Myelofibrosis

09:58 – Ciro's interest in the field

13:39 – Disease drivers & progression to aggressive states

17:40 – Inflammation and the bone marrow environment

22:19 – Novel targets

27:45 – Splenomegaly and MPNs

32:19 – Translational research

36:25 – Future of myelofibrosis management

38:51 – Ciro's three magic wishes

Vidur Mahajan joins host Catherine Glass to explore how imaging AI earns clinician trust. Learn how CARPL.ai bridges the gap between research and practice, ensures transparency, and empowers radiologists to evaluate and deploy AI safely.

Timestamps:
00:00 – Introduction

01:01 – Behind CARPL.ai

03:55 – Addressing scepticism

06:47 – Barriers in AI implementation

09:29 – Ensuring transparency

11:43 – Common challenges