Episodios

  • Deep Dive 1/3: Understanding Gravity Intolerance
    Nov 10 2025

    In this first deep dive, Spiegel unpacks his bold hypothesis: that irritable bowel syndrome and similar disorders could stem from gravity intolerance. He discusses his self-experiment simulating stronger gravity, the role of core strength in symptom relief, and how altitude affects gastrointestinal conditions.

    Timestamps:
    01:04 – What is gravity intolerance?

    02:55 – Gravity and chronic conditions

    06:18 – Gravity and irritable bowel syndrome

    09:29 – Self experiment

    12:37 – Gravity's effect on pregnancy

    16:43 – How should patients and clinicians think about gravity?

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    21 m
  • Quickfire: How Does Gravity Harm Health?
    Nov 10 2025

    Brennan Spiegel answers rapid-fire questions about the effects of gravity on the human body and mind. From fatigue to irritable bowel syndrome to mental health, learn why gravity might be one of medicine's most overlooked forces, and how virtual reality is helping researchers study its effects.

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    8 m
  • The Next Era of Diagnosis: From Leadership to Legacy
    Nov 6 2025

    In this final episode, Ghatak and Olivo reflect on leadership, mentorship, and the legacy of innovation in diagnostics. Discover what drives them to keep pushing the boundaries of healthcare technology.

    Timestamps:

    00:00 - Introduction

    00:45 - Good leadership

    05:04 - Advice for young professionals

    07:34 - Diagnostic gaps

    09:34 - Maintaining motivation

    10:33 - ImmunoProfile legacy

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    14 m
  • The Next Era of Diagnosis: Real-World Applications
    Nov 6 2025

    From lab to clinic, how do diagnostic breakthroughs make a real-world impact? Ghatak and Olivo explore bridging the gap between development and implementation, managing risk, and balancing innovation with ethics in patient care.

    Timestamps:

    00:00 – Introduction

    00:43 – Implementation challenges

    02:40 – Strategic risk

    03:46 – Trial and error

    06:21 – Ethical dilemmas

    09:46 – Lessons learned

    11:00 – Successful innovation

    13:12 – 'Good' diagnostics

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    17 m
  • Onc Now: Episode 28: Challenges and Hope in Kidney Cancer Research
    Nov 5 2025
    In this episode, Jonathan Sackier speaks with Brian Rini, Chief of Clinical Trials at Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA, and an internationally known leader in genitourinary oncology. The discussion explores the evolution of kidney cancer treatment, highlighting breakthroughs in immunotherapy, targeted therapy, and precision oncology. Rini shares insights from landmark clinical trials, his passion for translational research, and the challenges of broadening trial access. He also reflects on the future of the field, including the role of artificial intelligence, biomarker-driven strategies, and his hopes for advancing patient outcomes worldwide. Timestamps:   00:00 – Introduction 01:10 – Key insights into kidney cancer 03:50 – Brian's career journey 07:40 – One piece of career advice 10:40 – Diagnosis of kidney cancer 12:04 – Treatment landscape for kidney cancer 17:00 – Landmark trials in renal cell carcinoma 19:18 – Precision-based approach in trial design and selection 23:40 – Translational research 26:35 – Clinical trial recruitment 30:25 – Diversity in kidney cancer research 32:27 – ESMO 2025 highlights 35:00 – Potential of AI in trial design and recruitment 36:43 – Uncovered areas for research 38:12 – Brian's three wishes for healthcare
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    41 m
  • Cold Truths of Endometriosis and Cryoablation: Hope, Hype or Hard Evidence?
    Nov 4 2025

    In this EMJ podcast, experts discuss challenges within endometriosis care and cryoablation as an emerging treatment option. Navigating disease burden, current management limitations, the promise of precision imaging and minimally invasive techniques, the conversation highlights early clinical experience, ongoing research, and future directions for integrating cryoablation into endometriosis care.

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    23 m
  • Pollution, Pregnancy, and Paediatrics: Actioning Change in the Clinic
    Nov 3 2025

    How can clinicians make a difference? Woodruff outlines practical steps, screening tools, and advocacy approaches that can help reduce patients' exposure to harmful chemicals. She also reflects on policy progress and shares trusted resources for environmental health education.


    Timestamps:
    01:16 – Action and change

    06:39 – How to reduce patients' toxic exposure

    08:27 – Practical tools and screening

    13:46 – Advocacy and policy

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    19 m
  • Pollution, Pregnancy, and Paediatrics: Who's Most at Risk?
    Nov 3 2025

    Which communities bear the brunt of pollution during pregnancy and early life? Woodruff explores the links between socioeconomic status, genetics, and environmental exposure, illustrating how 'double jeopardy' and environmental injustice compound health risks for vulnerable families.

    Timestamps:
    01:36 – Pre-term birth

    06:07 – Gut microbiome

    11:37 – Genetic factors

    12:59 – Double jeopardy

    14:26 – Environmental injustice

    14:54 – Cancer valley

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    20 m