Episodios

  • #13 Length of daylight and positive mood: the serotonin story
    Jul 10 2024

    In this episode, I cover a paper by Green et al., 2015. The title of the paper is "Photoperiod Programs Dorsal Raphe Serotonergic Neurons and Affective Behaviors." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/25959961/. You may access the paper by clicking on the icons under the "Full Text Links" tab.

    Here are the webpages of Dr. McMahon and Dr. Grueter respectively: https://www.mcmahonlab.org and https://www.vumc.org/grueter-lab/welcome-grueter-lab. You may access other publications and the current focuses of their lab by following the links.

    The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

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    21 m
  • #12 Seasonal change in daylight on reward and motivation: the dopamine story
    Jul 3 2024

    In this episode, I cover a paper by Jameson et al., 2023. The title of the paper is "Photoperiod Impacts Nucleus Accumbens Dopamine Dynamics." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/36781229/. You may access the paper by clicking on the icons under the "Full Text Links" tab.

    Here are the webpages of Dr. McMahon and Dr. Grueter respectively: https://www.mcmahonlab.org and https://www.vumc.org/grueter-lab/welcome-grueter-lab. You may access other publications and the current focuses of their lab by following the links.

    The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

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    23 m
  • #11 Could KLOTHO be the long-awaited Alzheimer's drug?
    Jun 13 2024

    In this episode, I cover a paper by Zhao et al., 2020. The title of the paper is "Klotho overexpression improves amyloid-β clearance and cognition in the APP/PS1 mouse model of Alzheimer's disease." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/32964663/. You may access the paper by clicking on the icons under the "Full Text Links" tab.

    Here is the webpage of Dr. Jun-Rong Du: https://www.scu.edu.cn/medical/info/1015/1030.htm You may access other publications and the current focuses of their lab by following the links.

    The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

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    18 m
  • #10 The Western diet and Alzheimer's disease (Second half with Stedman Stephens)
    Jun 5 2024

    In this episode, Stedman and I cover the second half of a paper by Poxleitner et al., 2024. The title of the paper is "Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/38745337/. You may access the paper by clicking on the icons under the "Full Text Links" tab.

    Here are the webpages of Dr. Herfert and Dr. Beziere respectively:

    http://www.isct.uni-tuebingen.de/wsic/research/research-groups/neurology/functional-and-metabolic-brain-imaging

    http://www.isct.uni-tuebingen.de/wsic/research/research-groups/immunology-inflammation/inflammation

    You may access other publications and the current focuses of their lab by following the links.

    The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

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    21 m
  • #9 The Western diet and Alzheimer's disease (First half with Stedman Stephens)
    May 29 2024

    In this episode, Stedman and I cover the first half of a paper by Poxleitner et al., 2024. The title of the paper is "Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/38745337/. You may access the paper by clicking on the icons under the "Full Text Links" tab.

    Here are the webpages of Dr. Herfert and Dr. Beziere respectively:

    http://www.isct.uni-tuebingen.de/wsic/research/research-groups/neurology/functional-and-metabolic-brain-imaging

    http://www.isct.uni-tuebingen.de/wsic/research/research-groups/immunology-inflammation/inflammation

    You may access other publications and the current focuses of their lab by following the links.

    The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

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    21 m
  • #8 APOE4 and Alzheimer's disease
    May 15 2024

    In this episode, I cover a paper by Wang et al., 2021. The title of the paper is "Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/33831349/. You may access the paper by clicking on the icons under the "Full Text Links" tab.

    Here is the webpage of the Holtzman lab: https://holtzmanlab.wustl.edu. You may access other publications and the current focuses of the lab by following the link.

    The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

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    14 m
  • #7 Neuroinflammation in Alzheimer's disease
    May 8 2024

    In this episode, I cover a paper by Kummer et al., 2021. The title of the paper is "Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/34825707/. You may access the paper by clicking on the icons under the "Full Text Links" tab.

    Here is the webpage of the Heneka lab: https://www.iiibonn.de/michael-heneka-lab/michael-heneka-lab-science. You may access other publications and the current focuses of the lab by following the link.

    The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

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    20 m
  • #6 How does the gut microbiome contribute to Alzheimer's disease?
    May 1 2024

    In this episode, I cover a paper by Grabrucker et al., 2023. The title of the paper is "Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis." Here is the PubMed link for the article https://pubmed.ncbi.nlm.nih.gov/37849234/. You may access the paper by clicking on the icons under the "Full Text Links" tab.

    Here is the webpage of the Nolan lab: https://research.ucc.ie/profiles/C003/ynolan. You may access other publications and the current focuses of the lab by following the link.

    The music for this podcast was composed by Marko Krtinic, and if you would like to check out his work and support him, please visit his Spotify account at https://open.spotify.com/artist/6bJaFvgKIirKMoox9cGHWC?si=_Ou5UC-BRXebl_S7AH-kGg.

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    16 m