Episode Summary

In today’s episode Jeremy and Sass talk about the anaphylactic shock state. They discuss the most common triggers for anaphylaxis, how it occurs at the cellular level, the signs and symptoms associated with anaphylaxis, and most important…how to manage this critical event.

References

1. Macy E. Penicillin and B-lactam allergy: Epidemiology and diagnosis. Curr Allergy Asthma Rep. 2014;14(11):476.
2. Sadleir PHM, et al. Anaphylaxis. To neuromuscular blocking drugs: Incidence and cross reactivity in Western Australia from 2002-2011. British Journal of Anaesthesia. 2013;110(6):981-87.
3. Dewachter P, et al. Anaphylaxis and anesthesia: controversies and new insights. Anesthesiology. 2009;111:1141-50. APSF Newsletter, June 2018.
4. Tazazawa T, et al. Sugammadex and rocuronium induced anaphylaxis. J Anesth. 2016;30:290-97.
5. Reber LL, et al. The pathophysiology of anaphylaxis. J Allergy Clin Immunol. 2017;140:335-48.

About The Nurse Anesthesia

For anyone who wants to learn or review anesthesia concepts…we will set you up for a successful educational jOURney by providing short, meaningful courses to accelerate your nurse anesthesia learning, tackle your training, and become the successful CRNA you have always dreamed of. Let's do this together. It's Go Time!

Sign up for The Nurse Anesthesia Courses

Learn more about The Nurse Anesthesia at www.thenurseanesthesia.com

Comments or Suggestions?

We’re here to help you improve your anesthesia learning and practice, and we want to make sure our content is relevant for you. Click here to share your comments and suggestions.

Legal Disclaimer

The Nurse Anesthesia INC. expressly disclaims any liability in connection with the use of any content in its podcasts, social media posts, and all other published content by any third party.

Music by Alex Grohl

Mixed & Edited by Next Day Podcast
info@nextdaypodcast.com

Anesthesia induction agents are essential anesthesia medications that anesthesia providers need to learn about and understand so they can select the correct medication for the right patient/situation. The primary induction agents used in today’s anesthesia practice include: Propofol, Etomidate, and Ketamine…we refer to these as “The Knock Out Buch!”

Without a doubt, propofol is used more often than any other anesthesia induction agent.

In today’s episode, we talk about the pharmacokinetics, pharmacodynamics, mechanism of action, and clinical indications of each one of the anesthesia induction medications. Get ready, because this is an episode filled with key concepts and important information used for exams that is hard to find!

References

1. Nagelhout J, Intravenous Induction Agents. Elisha S, Heiner J, Nagelhout J, eds. Nurse Anesthesia. 7th ed. Elsevier; 2023:101-117.
2. Hailu S, et al. Effectiveness of ketofol versus propofol induction on hemodynamic profiles in adult elective surgical patients: A Randomized Controlled Trial. International Journal of Surgery Open. Vol 37, 2021.
3. Carlson P. Spreading depolarization in acute brain injury inhibited by ketamine: a prospective, randomized, multiple crossover trial. J Neurosurg. 2018 May 25;1-7.
4. Albanese J., et al., Ketamine Decreases Intracranial Pressure and Electroencephalographic Activity in Traumatic Brain Injury Patients during Propofol Sedation . Anesthesiology 1997; 87:1328–1334 doi: https://doi.org/10.1097/00000542-199712000-00011
5. Gregers M., et. al., Ketamine as an Anesthetic for Patients with Acute Brain Injury: A Systematic Review. Neurocrit Care. 2020 Aug;33(1):273-282. doi: 10.1007/s12028-020-00975-7.

About The Nurse Anesthesia

For anyone who wants to learn or review anesthesia concepts…we will set you up for a successful educational jOURney by providing short, meaningful courses to accelerate your nurse anesthesia learning, tackle your training, and become the successful CRNA you have always dreamed of. Let's do this together. It's Go Time!

Sign up for The Nurse Anesthesia Courses

Learn more about The Nurse Anesthesia at www.thenurseanesthesia.com

Comments or Suggestions?

We’re here to help you improve your anesthesia learning and practice, and we want to make sure our content is relevant for you. Click here to share your comments and suggestions.

Legal Disclaimer

The Nurse Anesthesia INC. expressly disclaims any liability in connection with the use of any content in its podcasts, social media posts, and all other published content by any third party.

Music by Alex Grohl

Mixed & Edited by Next Day Podcast
info@nextdaypodcast.com

In this episode we highlight the various difficult airway algorithms and failed airway checklists developed by professional airway organizations. These tools used by anesthesia providers to develop their personal airway management plans and to help guide decision making in the event of a difficult or failed airway.

References

1. Apfelbaum JL, et.al. 2022 American Society of Anesthesiologists Practice Guidelines for Management of the Difficult Airway. Anesthesiology. 2022 Jan 1;136(1):31-81. doi: 10.1097/ALN.0000000000004002. PMID: 34762729.
2. Frerk C, et al. Difficult Airway Society intubation guidelines working group. Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults. Br J Anaesth. 2015 Dec;115(6):827-48. doi: 10.1093/bja/aev371.
3. Jung H. A comprehensive review of difficult airway management strategies for patient safety. Anesth Pain Med (Seoul). 2023 Oct;18(4):331-339. doi: 10.17085/apm.23123.
4. Law JA, et. al. Canadian Airway Focus Group. Canadian Airway Focus Group updated consensus-based recommendations for management of the difficult airway: part 2. Planning and implementing safe management of the patient with an anticipated difficult airway. Can J Anaesth. 2021 Sep;68(9):1405-1436. doi: 10.1007/s12630-021-02008-z.
5. Law JA, et. Al. Canadian Airway Focus Group. Canadian Airway Focus Group updated consensus-based recommendations for management of the difficult airway: part 1. Difficult airway management encountered in an unconscious patient. Can J Anaesth. 2021 Sep;68(9):1373-1404. doi: 10.1007/s12630-021-02007-0.

Resources/information discussed in podcast

| Ariadne Labs OR Crisis Checklists: https://www.ariadnelabs.org/safe-surgery-safe-systems/surgical-safety/or-crisis-checklists/or-crisis-checklist-download/
Stanford Emergency Manual: https://emergencymanual.stanford.edu/
The Nurse Anesthesia Failed Airway Checklist:


About The Nurse Anesthesia

For anyone who wants to learn or review anesthesia concepts…we will set you up for a successful educational jOURney by providing short, meaningful courses to accelerate your nurse anesthesia learning, tackle your training, and become the successful CRNA you have always dreamed of. Let's do this together. It's Go Time!

Sign up for The Nurse Anesthesia Courses

Learn more about The Nurse Anesthesia at www.thenurseanesthesia.com

Comments or Suggestions?

We’re here to help you improve your anesthesia learning and practice, and we want to make sure our content is relevant for you. Click here to share your comments and suggestions.

Legal Disclaimer

The Nurse Anesthesia INC. expressly disclaims any liability in connection with the use of any content in its podcasts, social media posts, and all other published content by any third party.

Music by Alex Grohl

Mixed & Edited by Next Day Podcast
info@nextdaypodcast.com