This episode features Dr. Gary Fettke, who specializes in treating inflammation and chronic disease with nutrition. Let our sponsor, BetterHelp, connect you to a therapist who can support you - all from the comfort of your own home. Visit https://www.betterhelp.com/primalpodcast and enjoy a special discount on your first month. Dr. Fettke is an orthopedic surgeon who asserts inflammation is at the heart of all disease, and our modern diet is to blame. In this episode, Dr. Fettke discusses the most harmful foods we eat every day, which are slowly elevating blood sugar, causing insulin resistance, and disease in all areas of the body. Dr. Fettke explains that if your blood sugar is elevated, it affects every part of the body, including the brain, the heart, eyes, and every cell. Access the full show notes, including referenced articles, books, and additional resources: https://www.theprimal.com/lab/the-most-harmful-foods-causing-inflammation-chronic-disease Dr Fettke discusses where inflammation comes from, particularly from three sources: fructose, glucose, and polyunsaturated oils. Dr Fettke also breaks down the mechanism by which fructose damages the mitochondria of every cell and the science behind why fructose is as dangerous as glucose. Dr Fettke also discusses carbohydrates and the dose that is the poison. This episode is important for those who want to fix metabolic disease with nutrition. You will learn the simple science of fructose and glucose, how they cause disease, and the simple nutritional and lifestyle solutions to fix metabolic damage.

In this episode, my guest is Dr. Casey Means, MD, a physician trained at Stanford University School of Medicine, an expert on metabolic health and the author of the book, Good Energy. Dr Casey Means Book 'Good Energy': https://amzn.to/4dXiye1 Dr Means has decades of experience understanding the root cause of the most chronic health diseases, namely cancer, Alzheimer's, dementia, heart disease, and obesity. Dr Means asserts our healthcare system, doctors, big pharma, and big food are at the core of our current healthcare crisis, which focuses on profit, not root-cause healing. Access the full show notes, including referenced articles, books, and additional resources: https://www.theprimal.com/lab/the-root-cause-of-chronic-disease-and-the-link-with-mitochondria Dr. Means discusses how all the diseases we see are the root cause of metabolic dysfunction. Even though we might see different symptoms of chronic inflammation, it all traces back to the health of our mitochondria. The first section of this episode highlights why 93% of Americans are sick and why subspecialized medicine is destroying our health. Dr. Means outlines three main industries that are at the core of healthcare: big pharma, big food, and medical doctors, and the trifecta of what's causing metabolic disease: oxidative stress, metabolic dysfunction, and inflammation. The second section of this episode explains metabolic dysfunction (in simple terms) and how we can fix our mitochondria. Dr. Means explains specific science-based protocols, including nutrition, movement, light therapy, and emotional well-being, and how they impact the mitochondria. This episode is important if you have a metabolic condition in which the healthcare system has failed you. You will learn the simple science of how to improve your mitochondria through science-based nutrition and lifestyle tools for optimal health and longevity.

This episode features Dr. David Harper, who will discuss the root cause of cancer and the nutrition protocols to starve cancer cells. Dr Harper will discuss the truth about cancer and why cancer is not a genetic disease. Dr. Harper will explain the gene mutations that occur from cancer cells and the science behind metabolic therapy to starve cancer cells, reduce tumor (carcinomas) size, and ultimately prevent cancer. Access the full show notes, including referenced articles, books, and additional resources: https://www.theprimal.com/lab/starve-cancer-cells-heal-the-body-with-nutrition Dr. Harper explains the three axes of what causes cancer, hyperinsulinemia, hyperglycemia, and chronic inflammation, and the mechanism by which all three lead to chronic disease, which includes cancer but also many other chronic health conditions like dementia, heart disease, stroke, and obesity. Dr Harper will share the science behind the Ketogenic diet as a nutritional protocol to starve cancer cells and the role of Beta-Hydroxybutyrate, MTOR, and AMPK in preventing cancer (via up-regulation and down-regulation of certain mechanisms). This episode is important for understanding how to actively treat cancer with nutrition, the science of metabolic therapy and mitochondria, and how to prevent cancer through lifestyle changes.

This episode features Dr. Annette Bosworth (Dr. Boz), who specializes in treating insulin resistance with a high fat Ketogenic Diet. Dr Boz has over 20 years of clinical experience treating the underlying root cause of many chronic health problems: insulin resistance. In this episode, Dr Boz explains how high insulin levels lead to heart attacks, strokes, dementia, high blood pressure, hormonal dysregulation, and the mechanism by which this happens. Access the full show notes, including referenced articles, books, and additional resources: https://www.5minutebody.com/lab/spot-insulin-resistance-no-labs-required Dr Boz explains exactly what the hormone insulin is, its role in the body, and, most importantly, how insulin levels rise over time. We discuss the role of dietary carbohydrates and processed foods and how both feed insulin resistance. Dr. Boz also explains the 10 signs and symptoms of insulin resistance so you can spot high insulin levels visibly without requiring blood work or labs. Dr. Boz explains the role of a Ketogenic Diet and why ketosis (ketones) is extremely important for healing chronic inflammation. We discuss the Dr. Boz ratio, which is an adaptation of the GKI index (also used in metabolic therapy for the treatment of cancer), and what numbers you need to lose weight, heal chronic inflammation, and reverse insulin resistance. This episode is important if you have insulin resistance. You will learn the simple science of how insulin levels become chronically elevated, how this relates to most chronic diseases and the simple signs and symptoms to spot insulin resistance.

This episode features Dr Jason Fung, a Nephrologist (Kidney Doctor) who has spent over 25 years researching the best way to lose weight and prevent disease. In this episode, Dr Fung discusses the causes of obesity and how hormones play a vital role in fat storage and weight gain. Dr Fung discusses the difference between the hormonal theory and the calories theory, pertaining to the best way to lose adipose fat and regain metabolic health. Access the full show notes, including referenced articles, books, and additional resources: https://www.5minutebody.com/lab/the-root-cause-of-obesity-chronic-disease-and-how-fasting-prevents-it Dr Fung discusses the key hormone of insulin, how elevated levels of insulin in the body lead to chronic inflammation, and the physiology of how this happens. Dr Fung explains how certain foods we eat elevate insulin and cause us to store fat in the fat cells. And while what we eat matters, when we eat is also important to release adipose tissue (body fat). Dr Fung discusses the role of intermittent fasting, extended fasting, and autophagy to reduce inflammation and why the consumption of too much protein can inhibit autophagy and mitophagy. Dr. Fung also discusses the role of common weight loss medications like Ozempic and their effect on weight loss and insulin resistance. This episode is important for anyone who is overweight, those who have tried every diet or count calories and failed, and who seek to know the science behind how to lose weight and keep it off. You will learn the science of lipolysis (how the body burns fat) and effective dietary and lifestyle protocols to improve metabolic health and fix obesity.

This episode features Dr. Nathan Bryan, an expert in Nitric Oxide who specializes in reversing metabolic disease with the natural production of Nitric Oxide. Dr Bryan has spent over 20 years researching the molecule of Nitric Oxide and it's impact on cardiovacular health as well as the prevent of chronic health conditions, namely heart attacks, strokes, dementia and Alzheimer's. Access the full show notes, including referenced articles, books, and additional resources: https://www.5minutebody.com/lab/nitric-oxide-the-holy-grail-of-inflammation-disease-how-to-naturally-increase-nitric-oxide In this episode Dr Bryan discusses the two ways our body produces Nitric Oxide via the Nitric Oxide Synthase pathway and the enterosalivary nitrate-nitrite-nitric oxide (NO) pathway. Dr Bryan explains how both Nitric Oxide pathways promote vasodilation (the widerning of the arteries) and help with blood pressure regulation. We discuss how you lose Nitric Oxide production as we age through western medicine, diet, and lifestyle factors. Dr Bryan discusses the dangers of using antiseptic mouthwash on the oral microbiome, the use of antacids and the connection to dementia, heart attacks and stroke and dietary protocols to increase Nitric Oxide production. This episode is important for anyone who seeks to understand the cause of chronic disease, and for those who seek to optimise their heart and cardiovascular function. You will learn the science of the four hallmarks of chronic inflammation which is leading to heart attacks, stroke and dementia, the science of how Nitric Oxide prevents all chronic disease, and how to naturally increase Nitric Oxide production.

Dr Cywes has spent over 20 years researching metabolic disease and the cause of heart attacks and strokes. This episode features Dr Robert Cywes, a double board certified surgeon who specialises in preventing metabolic disease, obesity, and chronic inflammation. Access the full show notes, including referenced articles, books, and additional resources: https://www.5minutebody.com/lab/dr-rob-cywes-the-root-cause-of-heart-attacks-strokes-and-how-to-prevent-it This episode discusses the cause of heart attacks and strokes and key metabolic markers to prevent cardiovascular events. In this episode, Dr Cywes discusses the two main causes of heart attacks and strokes and explains why early recognition is critical for prevention. We also discuss how early screening at age 40 (or earlier) is important to ensure you are not at risk, including simple screening tests. We discuss the role of cholesterol and LDL cholesterol and its function in the body, as well as saturated fat, and why fat is essential for healing inflammation, and preventing heart disease. Dr Cywes also shares why a high fat Ketogenic Diet or Carnivore diet is optimal for the heart, hormones and your over health, and why consuming too much protein in the form of animal meat can be dangerous. This episode is important if you want to know the true causes of heart disease and stroke and for those who seek to optimise their heart and cardiovascular function. You will learn the science of what causes inflammation in the heart, and simple dietary strategies to prevent heart disease and strokes. 5 Minute Body Social & Website Instagram: https://www.instagram.com/5minutebody Twitter: https://twitter.com/5MinuteBody Website: https://www.5minutebody.com Timestamps: 00:00 Intro 02:25 Biggest cause of heart attack & strokes 07:41 LDL cholesterol, it’s function 15:07 Blood pressure + heart function 22:36 Sodium chloride (salt) on the heart 27:40 The energy every cell in the body needs 30:52 Saturated fat on the heart 37:15 Tool: The role of diet to prevent heart attacks & strokes 43:40 The first step to change your diet 44:51 Tool: Why you need to do high-fat 57:32 Risks of statins on the brain & diabetes 01:02:43 Ozempic is a better treatment than statins 01:04:55 Tool: The psychological impact of carbohydrates 01:10:03 Find Dr Rob Cywes #heartattack #stroke

This episode features Dr. Georgia Ede, a Harvard-trained psychiatrist specializing in mental health and the brain. Dr Ede has spent 25 years researching the role of a Ketogenic Diet and the Carnivore Diet and its impact on mental illness and brain disease, namely dementia, depression, anxiety, ADHD, and bipolar disorder. Access the full show notes, including referenced articles, books, and additional resources: https://www.5minutebody.com/lab/dr-georgia-ede-diet-nutrition-for-mental-health-memory-and-brain-function This episode discusses how the brain functions at an optimal state and the 5 neurotransmitters responsible for mood and optimal brain function. Dr. Ede also shares the worst foods people are eating every day that destroys brain function and lead to common mental illnesses like dementia, Alzheimer’s, anxiety, and depression. We also discuss the side effects of medications, namely statins, and their negative effects on the brain.