This Week in Virology Por arte de portada

This Week in Virology

De: Vincent Racaniello
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  • Resumen

  • TWiV is a podcast about viruses - the kind that make you sick.
    Vincent Racaniello 2022
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Episodios
  • TWiV 1133: Gain of function makes us safer

    TWiV 1133: Gain of function makes us safer
    Jul 21 2024

    TWiV reviews cases of measles in Brooklyn NY and Washington DC, stalling of global childhood vaccination, licenses H5N1 vaccines protect against circulating strains, viruses traveling without passports. OC43 SARS-CoV- 2 spike replacement virus as an improved BSL-2 proxy virus for SARS-CoV-2 neutralization assays, and deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex.

    Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • MicrobeTV Discord Server
    • Measles in Brooklyn NY (ABC)
    • Measles in Washington DC (DC Health)
    • Global childhood immunization stalls (WHO)
    • Licensed H5N1 vaccines protect against circulating strains (Nat Med)
    • Viruses moving without passports (European CDC)
    • OC42-SARS-CoV-2 replacement spike virus (PNAS)
    • Deep mutational scanning of Lassa virus glycoprotein (Immunity)
    • Letters read on TWiV 1133
    • Timestamps by Jolene. Thanks!
    Weekly Picks

    Dickson – Elemental sulfur found on Mars
    Kathy – Lennette Lectures at ASV, including Gail Wertz, ASV 2024
    Rich – Electricity maps (Opinions: Nuclear Waste Is Misunderstood; Should We Be Worried About Nuclear Waste?)
    Alan – Nature sent an investigative reporter to a predatory conference
    Vincent – Coal-filled trains are likely sending people to the hospital

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.
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    1 h y 59 m
  • TWiV 1132: Clinical update with Dr. Daniel Griffin

    TWiV 1132: Clinical update with Dr. Daniel Griffin
    Jul 20 2024
    In his weekly clinical update, Dr, Daniel Griffin reviews President Biden’s case of COVID, reviews recent statistics on SARS-CoV-2 infection, discusses post-acute sequelae after infection during pregnancy, the use of nirmatrelvir-ritonavir for post-exposure prophylaxis, where to find Pemgarda, effectiveness of combined nirmatrelvir-ritonavir-molnupiravir treatment, effectiveness of Ensitrelvir in reducing severe outcomes in outpatients at high risk for COVID-19, effectiveness of combined nirmatrelvir-ritonavir-molnupiravir treatment in patients hospitalized with COVID-19, CDC update of Long COVID Basics page, postacute sequelae of SARS-CoV-2 infection in the pre-delta, delta, and omicron eras, Long COVID risk has dropped over time but remains substantial, efficacy of antivirals, corticosteroids, and mAbs as acute COVID treatments in reducing the incidence of long COVID, and the interplay between diet and the gut microbiome: implications for health and disease. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode President Biden has COVID (CNN, USA Today)COVID-19 national trend (CDC)COVID-19 deaths (CDC)Post–acute sequelae of COVID after infection during pregnancy (OB & Gyn)Oral nirmatrelvir–ritonavir as postexposure prophylaxis for Covid-19 (NEJM)Pemgarda infusion center locator (Pemgarda)Unable to access pemgarda, gotta call Daniel (microbeTV) CDC Quarantine guidelines (CDC)Early phase of SARs-CoV-2 infection (COVID.gov) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society)Drug interaction checker (University of Liverpool) Combined treatment of COVID reduces molnupiravir-induced mutagenicity (J Inf Dis)Effectiveness of ensitrelvir in reducing severe outcomes in outpatients at high risk for COVID-19 (Inf Dis Therapy)Comparative effectiveness of combination therapy with nirmatrelvir–ritonavir and remdesivir versus monotherapy (Lancet)Molnupiravir safety and efficacy (JMV)Convalescent plasma recommendation for immunocompromised (ID Society) Isolation guidance (CDC)Managing healthcare staffing shortages (CDC)Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID is defined (National Academies)Long COVID: the ANSWERS! (longcovidtheanswers.com) The FACTS: post COVID-19=long COVID? (WHO)The BASICS of long COVID-19 (CDC)Postacute sequelae of SARS-CoV-2 infection in the pre-delta, delta, and omicron eras (NEJM)Long Covid risk has dropped over time but remains substantial (CNN)Efficacy of antivirals, corticosteroids, and mAbs as acute COVID treatments in reducing the incidence of long COVID (Clin Micro Inf)Diet and the gut microbiome: implications for health and disease (Nat Rev Micro)Contribute to our Floating Doctors fundraiserLetters read on TWiV 1132Dr. Griffin’s COVID treatment summary (pdf)Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
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    41 m
  • TWiV 1131: Mootant influenza H5N1 virus

    TWiV 1131: Mootant influenza H5N1 virus
    Jul 14 2024

    TWiV reviews the potential impact on science of the Supreme Court ruling in the Chevron decision, measles in New Hampshire and Vermont, new who proposed terminology for respiratory pathogen transmission, and pathogenicity and transmission of bovine H5N1 influenza virus.

    Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • MicrobeTV Discord Server
    • Articles on Chevron decision (one, two, three)
    • Measles in New Hampshire and Vermont (NH DHHS)
    • Pathogenicity and transmission of bovine H5N1 virus (Nature)
    • Letters read on TWiV 1131
    • Timestamps by Jolene. Thanks!
    Weekly Picks

    Dickson – Stockholm Wood City
    Rich – “The Wide Wide Sea” by Hampton Sides
    Vincent – Tour de France stage 12

    Listener Picks

    Amy – Earth Forced from the Protective Heliosphere: What Do We know?

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.
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    1 h y 42 m
Ciencias Biológicas Historia Natural
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Love it!

Science first and yet entertaining.
Wonderful gang full of knowledge and joy for related topics.

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Very good science podcast!

The content is really good and always interesting with many great guests. Good job guys!

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Excellent Source

I found TWiV through the recommendation of another podcast. Like many I am a post covid follower and I have really appreciated TWiV as a source of current and accurate information. The clinical updates with Dr. Griffin are so useful . Dr Gritting uses language that I, a custodian i.e. not a science professional am able to understand. I find the clinical updates really ease my anxieties because finally I understand what is going on around me. Sometimes the other episodes I struggle to totally follow along but I always finish having learned something I didn't know before listening. Turns out virology and immunology is quite fascinating!

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Fun team

You need a background in Bio to enjoy this podcast, but if you are on the in you should have a great time.

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