Episodios

  • S6:EP0 Unseen Upside - Season 6 Trailer
    Oct 14 2025

    Get ready—Season 6 of Unseen Upside launches October 21.

    This season, we’re taking you behind the scenes to explore how AI is transforming our world. From labs and classrooms to clinics and fields, we’ll follow the capital and uncover how AI is driving the next chapter of human progress.

    Tune in for episode one on your favorite podcast platform, Tuesday, October 21.

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    4 m
  • S5:E8 Mini Episode | The Story of Saving the American Bison
    Oct 3 2025

    Once numbering in the tens of millions, the American bison was nearly driven to extinction by the early 1900s. But a coalition of conservationists, Native American communities, and private partners were determined to save the species.

    Join us for this mini episode of Unseen Upside: Investments Beyond Their Returns, as we share the remarkable story of the bison’s restoration alongside John Calvelli, Executive Vice President of Public Affairs at Wildlife Conservation Society.

    Stay tuned for Season 6 which explores the transformative impact of AI across industries—launching Tuesday, October 21. In the meantime, catch up on past episodes in our podcast feed!


    Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

    Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. Cambridge Associates delivers a range of portfolio management services, including outsourced CIO, non-discretionary portfolio management, staff extension, and asset class mandates.

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    10 m
  • S5:E7 Mini Episode | What Inspires Our Guests: Must-Read Books and Podcasts, Pt 2
    Aug 27 2025

    Summer isn't over just yet--Unseen Upside is bringing you Part 2 of our summer reading list!

    Tune in as we share more book recommendations from investors and entrepreneurs on the leading edge of healthcare.

    Check the show notes for links to all the recommendations, and catch up on past episodes in our podcast feed. Stay tuned for Season 6—launching soon.

    Featured Recommendations:

    • The Frozen River: A GMA Book Club Pick by Ariel Lawhon
    • The Hard Thing About Hard Things: Building a Business When There Are No Easy Answers by by Ben Horowitz
    • Zero to One: Notes on Startups, or How to Build the Future by Peter Thiel
    • Clayton M. Christensen’s Books
    • Fifty Miles from Tomorrow by William L. Iggiagruk Hensley
    • A Fortunate Man: The Story of a Country Doctor by John Berger

    Guests Include:

    • Theresa Hajer, Head of US Venture Capital Research at Cambridge Associates
    • Alyssa Jaffe, Partner at Seven Wire Ventures
    • Lucas Trout, Lecturer on Global Health and Social Medicine at Harvard Medical School


    Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

    Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. Cambridge Associates delivers a range of portfolio management services, including outsourced CIO, non-discretionary portfolio management, staff extension, and asset class mandates.

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    5 m
  • S5:E6 Mini Episode | What Inspires Our Guests: Must-Read Books and Podcasts, Pt 1
    Jun 27 2025

    As summer heats up, Unseen Upside brings you a special two-part mini-episode packed with inspiration for your reading and listening list. From thought-provoking explorations of social justice and capitalism to the latest in women’s sports and business innovation, this short episode is your guide to what’s fueling the minds and spirits of those driving change in healthcare, housing, and beyond.

    Whether you’re looking for your next great read, a podcast to spark new ideas, or just want to know what’s on the radar of industry leaders, this episode has you covered. Check the show notes for links to all the recommendations, and stay tuned for part 2 of our guests' summer picks soon!

    Featured Recommendations:

    • Weathering: The Extraordinary Stress of Ordinary Life in an Unjust Society by Dr. Arline T. Geronimus
    • James (Pulitzer Prize Winner) by Percival Everett
    • Outliers: The Story of Success by Malcolm Gladwell
    • Just Mercy: A Story of Justice and Redemption by Bryan Stevenson
    • A Brief History of Seven Killings (Booker Prize Winner): A Novel by Marlon James
    • Queens of the Court (The Women’s Hoops Show Podcast)
    • Americana: A 400-Year History of American Capitalism by Bhu Srinivasan
    • Acquired: Novo Nordisk (Ozempic), Season 14, Episode 1
    • Unseen Upside: Appetite for Change: The Obesity Epidemic Meets Biotech

    Guests Include:

    • Chavon Sutton, Managing Director, Sustainable & Impact Investing at Cambridge Associates
    • Lynne Chou O’Keefe, Founder and Managing Partner at Define Ventures
    • Tim Ortez, Chief Financial Officer of the Weingart Foundation
    • Margaret Anadu, Senior Partner at The Vistria Group
    • Jasmine Richards, Head of Diverse Manager Research at Cambridge Associates
    • Gunnar Esiason, Head of Patient Engagement at RAVen (RA Ventures)
    • Dean Dimizas, Partner in the Private Client Practice at Cambridge Associates


    Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

    Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. Cambridge Associates delivers a range of portfolio management services, including outsourced CIO, non-discretionary portfolio management, staff extension, and asset class mandates.

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    6 m
  • S5:E5 The Maternal Health Crisis: Investing for Change
    Dec 3 2024

    There’s a maternal health crisis in the United States, with high rates of maternal mortality, especially among marginalized communities. But what is being done to improve it?

    Through conversations with those on the front lines, we uncover the stark health inequities that exist in maternal healthcare and the developments created to tackle them. We also hear from mothers who have firsthand experience with Preeclampsia—a serious pregnancy complication and one of the many causes of maternal mortality— and one company on a quest to cure it.

    Guests include:

    • Scott Gottlieb, MD, Partner at New Enterprise Associates and Former FDA Commissioner
    • Scott Johnson, MD, Chief Executive Officer and Co-Founder at Comanche Biopharma
    • Jennell Lynch, Chief Executive Officer and Founder at Executive Doula Agency
    • Theresa Hajer, Head of US Venture Capital Research at Cambridge Associates


    Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

    Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. Cambridge Associates delivers a range of portfolio management services, including outsourced CIO, non-discretionary portfolio management, staff extension, and asset class mandates.

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    46 m
  • S5:E4 Digital Health: Transforming Care, Improving Access
    Nov 19 2024

    How will evolving digital technologies impact healthcare delivery, patient experience, and access to care?

    According to new venture-backed companies, they can advance health equity, democratize access, and empower individuals to take control of their health journey. Alongside industry pioneers and investors, we explore digital health advancements such as telemedicine, remote monitoring, and data-driven diagnostics that are all working to improve healthcare efficiencies.

    Join us as we uncover the potential of these technologies to improve healthcare outcomes for all.

    Guests include:

    • Lynne Chou O'Keefe, Founder & Managing Partner at Define Ventures
    • Siva Namasivayam, CEO & Co-Founder at Cohere Health
    • Chavon Sutton, Senior Investment Director in the Sustainable & Impact Investing Research Group at Cambridge Associates


    Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

    Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. Cambridge Associates delivers a range of portfolio management services, including outsourced CIO, non-discretionary portfolio management, staff extension, and asset class mandates.

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    38 m
  • S5:E3 From Barriers to Bridges: Rural Health Access
    Nov 5 2024

    Join us in Kotzebue, Alaska to explore the issue of rural healthcare and the inequities faced by these communities.

    We shine a light on innovative solutions aimed at improving rural healthcare delivery, like a program called Siamit that’s connecting cutting-edge medicine from Massachusetts General Hospital (MGH) and Harvard Medical School to the tribal regions of Alaska. We also look at the role of venture capital in driving advancements that promote access to healthcare for those living in rural parts of the country.

    Guests include:

    • Lucas Trout, Lecturer on Global Health and Social Medicine at Harvard Medical School
    • Susan Rawlings Molina, Co-Founder and CEO at GroundGame Health
    • Alyssa Jaffee, Partner at 7wireVentures


    Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

    Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. Cambridge Associates delivers a range of portfolio management services, including outsourced CIO, non-discretionary portfolio management, staff extension, and asset class mandates.

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    41 m
  • S5:E2 Drug Affordability: The High Cost of Healing
    Oct 22 2024

    Prescription drug prices in the United States are 2.78 times higher than in other developed countries, but why?

    We untangle the barriers surrounding drug affordability and find out why accessing life-saving medications is costly to so many. Joined by experts, advocates, and one Cystic Fibrosis patient relying on expensive medication to live, we examine the complex factors contributing to the high costs of drugs, from research and development to pricing strategies and supply chain dynamics. We also investigate potential solutions to improve access and affordability without compromising on drug innovation.

    Guests include:

    • Peter Kolchinsky, Founder and Managing Partner at RA Capital
    • Gunnar Esiason, Head of Patient Engagement at RAVen (RA Ventures)
    • Dean Dimizas, Partner in the Private Client Practice at Cambridge Associates

    Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

    Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. Cambridge Associates delivers a range of portfolio management services, including outsourced CIO, non-discretionary portfolio management, staff extension, and asset class mandates.

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    43 m