At UHN’s Krembil Brain Institute, we have cared for many patients living with an extreme and heartbreaking facial pain disorder called trigeminal neuralgia. Patients often describe the pain as a lightning bolt to the face, or an electric shock. Some talk about the impact the disease has had on their family & relationships, including not being able to hug their loved ones, or kiss their children goodnight.

In today’s episode, we discuss how AI is helping researchers look for patterns and clues to treat patients living with trigeminal neuralgia and other chronic pain disorders.

Featuring:
Dr. Mojgan Hodaie – Neurosurgeon and senior scientist with UHN’s Krembil Brain Institute and the Greg Wilkins-Barrick Chair in International Surgery at UHN. Dr. Hodaie is also a Professor and the Postgraduate Medical Education Director for the Department of Surgery, at the University of Toronto’s Temerty Faculty of Medicine. Her surgical practice and research laboratory are dedicated to unraveling the underpinnings of the severe pain condition of trigeminal neuralgia, using advanced brain imaging technology. Her interest and dedication to education spans local, national and international activities.

Adriana Salazar - Graduated from The University of Western Ontario with a Bachelor of Management and Organizational Studies (BMOS) and has worked in the Finance Department at a law firm for the past 9 years. She is happily married and has a lovely daughter who just finished her first year of school. In her off time, she enjoys traveling back home to Colombia to see her family, painting in watercolours, and reading James Patterson novels in her hammock.

Additional resources:
Dr. Hodaie was interviewed on Season 1 of Your Complex Brain – “The most painful brain disease you’ve never heard of”
Toronto neurosurgeon marks 1,000th operation treating 'excruciating' facial pain syndrome
Dr. Hodaie recounts her journey from new immigrant to neurosurgeon (video)
Brain Aging in Fast Forward (UHN Research article)
Dr. Hodaie was a featured speaker at KBI’s first-ever ‘International Day of Women and Girls in Science’ event (video)

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!

The Lullaby Project brings together expectant mothers with professional songwriters to write, record, and perform an original lullaby for their baby. In 2017, Massey Hall and Roy Thomson Hall brought this heartwarming initiative to Toronto, and invited partners to participate, including Dr. Esther Bui, a neurologist who specializes in treating women with epilepsy. Today, we’re exploring whether participating in a project like The Lullaby Project can improve overall mental health for pregnant women who are living with epilepsy.

Featuring:
Dr. Esther Bui - Neurologist and epilepsy specialist focusing on women's neurological health; Assistant professor and clinician educator within the Division of Neurology, Department of Medicine at the University of Toronto. Dr. Bui founded Canada's first and only accredited Women's Neurology Fellowship at the University of Toronto. She is currently the co-Director of the Women's Neurology Fellowship Program and the Director of the Epilepsy Fellowship program.

Sharon Ng - Graduate student in neuroepidemiology at the Harvard Chan School of Public Health. She was previously a research assistant for Dr. Esther Bui at UHN, and worked with Dr. Bui to conceptualize the Lullaby Project Study. Sharon is now a collaborator on this study.

Julianne Hazlewood – CBC journalist for more than a dozen years, at newsrooms across Canada. Her true love is longform audio storytelling. Becoming a mother is the latest and most joyous chapter in her life.

Additional resources:
The Lullaby Project
The Lullaby Project Playlist
Julianne Hazlewood’s CBC radio documentary on White Coat Black Art
Dr. Esther Bui interviewed in Season 2 of Your Complex Brain podcast - A New Era in Women’s Brain Health: Closing the Gap on Delayed Diagnosis
Advancing Women’s Neurology through Education, Research and Advocacy (U of T story featuring Dr. Esther Bui & Dr. Aleksandra Pikula)
Dr. Esther Bui featured in UHN Foundation ‘Know Your Heroes’ series

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!

A stroke happens when there is a sudden blockage of blood flow to the brain or bleeding in the brain, which can result in symptoms such as numbness or weakness, trouble speaking, confusion, or dizziness. The type of symptoms one might experience depends largely on the type of stroke, and the area of the brain affected. But one thing is clear – despite the many advances in stroke care over the past 30 years, it's women who often suffer the most. 

In today’s episode, we discuss why women are more susceptible to stroke, what the unique risk factors are, and what women need more of to help them recover, not only from the medical condition, but the impacts to their careers, their mental health and their families.

Featuring:
Dr. Aleksandra Pikula, MD, PhD, is a neurologist and clinician-investigator at UHN’s Krembil Brain Institute and the newly appointed Jay and Sari Sonshine Chair in Stroke Prevention and Cerebrovascular Brain Health at UHN. Dr. Pikula advocates for a holistic approach to brain care, specifically targeting stroke and dementia prevention during midlife through evidence-based lifestyle medicine pillars.

Patrice Lindsay, PhD, is currently the Lead for the People With Lived Experience (PWLE) Engagement and Stroke Strategy at the Heart and Stroke Foundation of Canada. Dr. Lindsay leads strategic directions for health systems design and change for people with stroke and heart conditions across Canada and internationally.

Shruti Kothari is an actress born, raised, and residing in Toronto. Her career was focused largely on Shakespeare and Musical Theatre until her life took an unexpected turn when she suffered a life-altering brain hemorrhage and stroke at the age of 30. Over the past four years, Shruti has focused on reshaping her life and raising awareness about brain injuries in younger people.

Additional resources:
UHN’s Stroke Prevention Clinic
Dr. Pikula interviewed in the Your Complex Brain episode “The Rise of Stroke in Young Adults”
UHN Foundation video “Shruti’s journey back to the stage, with some help from Team UHN”
Heart and Stroke Foundation of Canada – Women’s Digital Hub
World Stroke Academy p

The Your Complex Brain production team is Heather Sherman, Jessica Schmidt, Dr. Amy Ma, Kim Perry, Sara Yuan, Meagan Anderi, Liz Chapman, and Lorna Gilfedder.

The Krembil Brain Institute, part of University Health Network, in Toronto, is home to one of the world's largest and most comprehensive teams of physicians and scientists uniquely working hand-in-hand to prevent and confront problems of the brain and spine, such as Parkinson's, Alzheimer's, epilepsy, stroke, spinal cord injury, chronic pain, brain cancer or concussion, in their lifetime. Through state-of-the-art patient care and advanced research, we are working relentlessly toward finding new treatments and cures.

Do you want to know more about the Krembil Brain Institute at UHN? Visit us at: uhn.ca/krembil

To get in touch, email us at krembil@uhn.ca or message us on social media:
Instagram - @krembilresearch
Twitter - @KBI_UHN
Facebook - https://www.facebook.com/KrembilBrainInstitute

Thanks for listening!