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New Books in Science

By: New Books Network
  • Summary

  • Interviews with Scientists about their New Books Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science
    New Books Network
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Episodes
  • Bobby Cherayil, "The Logic of Immunity: Deciphering an Enigma" (Johns Hopkins UP, 2024)
    Apr 16 2024
    Most of us appreciate the importance of the immune system yet have very little knowledge about how it actually works. If you fall into this camp and are curious to learn more about this intricate system, Bobby Cherayil's book is an excellent resource. The Logic of Immunity: Deciphering an Enigma was published in January 2024 by John Hopkins University Press. It gives a great overview of this complex system, including several findings from the recent years. It also points out the many areas of ongoing research and open questions. The book introduces the actors of the system and the many interactions between them: the various types of immune cells, the pathogens and pathogen-associated patterns they recognize, the cascade of events that ultimately leads to an immune response. The opening chapter explains (and visualizes!) where these cells are located. It explains how they contribute to the immune response, and how we broadly categorize them into innate and adaptive immunity. Chapters 2 and 3 discuss the innate immune system. We get to know the general concepts, like molecular patterns and receptors recognizing them. They describe in detail some well-studied mechanisms, like the LPS-TLR4 interaction. And we also learn the story of their research spanning multiple years and multiple discoveries building upon each other. Chapters 4-6 delve into the mechanisms of adaptive immunity and their main cell types: B- and T-lymphocytes. Have you ever wondered how the immune system is able to "remember" earlier infections? You'll find here both an overview of "immune memory" and a detailed description how B and T cell proliferate and specialize. Chapter 7 shows how these immune reactions are sometimes provoked by harmless substances - that's what we call allergy. Or even by human cells - that's what we call autoimmune diseases. The next chapters put the immune system into a bigger context. They discuss the variability of immunity across different individuals and the many reasons behind it. Genes, environment, past infections, life style. A particularly fascinating part of "the human ecosystem" is the microbiota. Its importance has been recognized only in the last two decades. Chapter 8 introduces really well this emerging field of study. Chapter 11 is dedicated to an immunology topic that affects all of us: vaccines. Building upon the knowledge from previous chapters, it explains how vaccines work. Throughout the book, we learn a lot both about the exciting developments and the open questions in the field of immunology. Chapter 12 gives a summary of some trends of the last decades and an outlook for the next big puzzles to tackle. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science
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    1 hr and 7 mins
  • Rasmus Winther, "Our Genes: A Philosophical Perspective on Human Evolutionary Genomics" (Cambridge UP, 2023)
    Apr 14 2024
    Situated at the intersection of natural science and philosophy, Our Genes: A Philosophical Perspective on Human Evolutionary Genomics (Cambridge University Press, 2023) explores historical practices, investigates current trends, and imagines future work in genetic research to answer persistent, political questions about human diversity. Readers are guided through fascinating thought experiments, complex measures and metrics, fundamental evolutionary patterns, and in-depth treatment of exciting case studies. The work culminates in a philosophical rationale, based on scientific evidence, for a moderate position about the explanatory power of genes that is often left unarticulated. Simply put, human evolutionary genomics - our genes - can tell us much about who we are as individuals and as collectives. However, while they convey scientific certainty in the popular imagination, genes cannot answer some of our most important questions. Alternating between an up-close and a zoomed-out focus on genes and genomes, individuals and collectives, species and populations, Our Genes argues that the answers we seek point to rich, necessary work ahead. Rasmus Grønfeldt Winther is a philosopher of science, researcher, writer, educator, diver, and explorer. He is Professor of Humanities at University of California, Santa Cruz and Affiliate Professor of Transformative Science at the GLOBE Institute at University of Copenhagen. Caleb Zakarin is editor at the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science
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    1 hr and 9 mins
  • Guru Madhavan on Wicked Problems and Engineering a Better World
    Apr 2 2024
    Peoples & Things host, Lee Vinsel, talks with Guru Madhavan, Norman R. Augustine Senior Scholar and Senior Director of Programs at the National Academy of Engineering, about his recent book, Wicked Problems: How to Engineer a Better World (W. W. Norton & Company, 2024). In Wicked Problems, Madhavan draws on a rich body of literature from the humanities and social sciences to think through how engineers can do a better job working on problems that include complex social and technical realities. The pair also talk about how Madhavan came to the National Academy of Engineering after working as an engineer and entrepreneur and some of his future work, including ongoing writing on the importance of maintenance and “grind problems” in engineering. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science
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    1 hr and 9 mins

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