TWiM reviews a case of E. faecium bacteremia treated with combination bacteriophage and antibiotic therapy, and how dopamine receptor D2 confers colonization resistance via microbial metabolites.

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

Guest: Mark O. Martin

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• Matters Microbial
• Distinct Fusobacterium dominates colorectal cancer (Nature)
• Bacterial subspecies that might drive colon cancer (Nature)
• A bacterial strain linked to colon cancer (Nature)
• Spatial perspective on bacteria in tumors (Nature)
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TWiM reviews a case of E. faecium bacteremia treated with combination bacteriophage and antibiotic therapy, and how dopamine receptor D2 confers colonization resistance via microbial metabolites.

Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson.

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• Vincent’s interviews at SXSW
• Bacteriophage and antibiotic therapy for E. faecium bacteremia (mBio)
• Dopamine receptor D2 confers colonization resistance (Nature)
• CDC’s Reports of Selected E. coli Outbreak Investigations
• Brett Finlay’s narrated EPEC animation
• Colonization resistance by gut microbial metabolome (ACS Chem Biol)
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TWiM discusses the identification of natural products from reconstructed ancient bacterial genomes, and how plant mRNAs move into a fungal pathogen via extracellular vesicles to reduce infection.

Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin.

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• Natural products from ancient bacterial genomes (Science)
• Plant mRNAs move into fungal pathogens (Cell Host Microb)
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Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv