Christian McCaffrey's calf/Achilles injury raises concerns for the San Francisco 49ers as they prepare for Week 1. NFL executives rank the 49ers #1 in the NFC, but the hosts question if they can sustain this with the Packers surprisingly close behind.

The episode breaks down the keys to victory against the Jets, emphasizing the need to avoid overusing injured players like McCaffrey, Brandon Aiyuk, and Trent Williams. The performance of new defensive line additions Javon Hargrave and Leonard Floyd is also scrutinized, along with the challenges facing the 49ers' offensive line.

San Francisco 49ers fans are treated to daily news and analysis with Locked On 49ers, hosted by football analyst Brian Peacock and former NFL/AFL cornerback Eric Crocker.

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Aaron Rodgers is back, making his highly anticipated debut with the New York Jets after last season's injury. Can the San Francisco 49ers' defense, potentially missing Talanoa Hufanga, limit Rodgers' explosive plays?

We break down the Jets' offensive strategy, the impact of Haason Reddick's holdout on their defensive line, and the 49ers' offensive holdouts like Brandon Aiyuk and Trent Williams. Tackling concerns for the Jets and the importance of protecting Rodgers are also on the table. Special teams could be the game-changer in this potential Super Bowl preview.

San Francisco 49ers fans are treated to daily news and analysis with Locked On 49ers, hosted by football analyst Brian Peacock and former NFL/AFL cornerback Eric Crocker.

Follow & Subscribe on all Podcast platforms…

🎧 https://link.chtbl.com/LO49ers?sid=YouTube

Locked On NFL League-Wide: Every Team, Fantasy, Draft & More

🎧 https://linktr.ee/LockedOnNFL

Follow Brian Peacock and Eric Crocker on Twitter, where they’ll be sharing the latest news about the Niners and talking with fans.

Twitter: twitter.com/BDPeacock, twitter.com/eric_crocker

Support Us By Supporting Our Sponsors!

PrizePicks

Go to https://prizepicks.onelink.me/LME0/LOCKEDONNFL and use code lockedonmlb to win $50 instantly when you play $5. You don't even need to win to receive your $50 bonus, it's guaranteed! Prizepicks. Run Your Game.

BetterHelp

This episode is sponsored by BetterHelp. Make your brain your friend, with BetterHelp. Visit BetterHelp.com/LOCKEDON today to get 10% off your first month.

LinkedIn

LinkedIn Jobs helps you find the qualified candidates you want to talk to, faster. Post your job for free at LinkedIn.com/LOCKEDONNFL. Terms and conditions apply.

eBay Motors

For parts that fit, head to eBay Motors and look for the green check. Stay in the game with eBay Guaranteed Fit at eBayMotors.com. Let’s ride. eBay Guaranteed Fit only available to US customers. Eligible items only. Exclusions apply.

Gametime

Download the Gametime app, create an account, and use code LOCKEDONNFL for $20 off your first purchase. Terms Apply. Download Gametime today. What time is it? Gametime.

FanDuel

Now through September 22nd, ALL FanDuel customers can bet FIVE DOLLARS and get a THREE WEEK free trial of NFL Sunday Ticket from YouTube and YouTube TV. Visit FANDUEL.COM/LOCKEDON to get started.

FANDUEL DISCLAIMER: 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN)

With the contract agreements for Trent Williams and Brandon Aiyuk, as well as Christian McCaffrey returning to practice, the San Francisco 49ers are primed for a Super Bowl run. after hitting 12 games in a row last year, weekly guest Nick Winkler makes his predictions for 2024.

San Francisco 49ers fans are treated to daily news and analysis with Locked On 49ers, hosted by football analyst Brian Peacock and former NFL/AFL cornerback Eric Crocker.

Follow & Subscribe on all Podcast platforms…

🎧 https://link.chtbl.com/LO49ers?sid=YouTube

Locked On NFL League-Wide: Every Team, Fantasy, Draft & More

🎧 https://linktr.ee/LockedOnNFL

Follow Brian Peacock and Eric Crocker on Twitter, where they’ll be sharing the latest news about the Niners and talking with fans.

Twitter: twitter.com/BDPeacock, twitter.com/eric_crocker

Support Us By Supporting Our Sponsors!

PrizePicks

Go to https://prizepicks.onelink.me/LME0/LOCKEDONNFL and use code lockedonmlb to win $50 instantly when you play $5. You don't even need to win to receive your $50 bonus, it's guaranteed! Prizepicks. Run Your Game.

BetterHelp

This episode is sponsored by BetterHelp. Make your brain your friend, with BetterHelp. Visit BetterHelp.com/LOCKEDON today to get 10% off your first month.

LinkedIn

LinkedIn Jobs helps you find the qualified candidates you want to talk to, faster. Post your job for free at LinkedIn.com/LOCKEDONNFL. Terms and conditions apply.

eBay Motors

For parts that fit, head to eBay Motors and look for the green check. Stay in the game with eBay Guaranteed Fit at eBayMotors.com. Let’s ride. eBay Guaranteed Fit only available to US customers. Eligible items only. Exclusions apply.

Gametime

Download the Gametime app, create an account, and use code LOCKEDONNFL for $20 off your first purchase. Terms Apply. Download Gametime today. What time is it? Gametime.

FanDuel

Now through September 22nd, ALL FanDuel customers can bet FIVE DOLLARS and get a THREE WEEK free trial of NFL Sunday Ticket from YouTube and YouTube TV. Visit FANDUEL.COM/LOCKEDON to get started.

FANDUEL DISCLAIMER: 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN)