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The Family That Couldn't Sleep
- A Medical Mystery
- Narrated by: Grover Gardner
- Length: 8 hrs and 45 mins
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Publisher's summary
What these strange conditions, including fatal familial insomnia, kuru, scrapie, and mad cow disease, share is their cause: prions. Prions are ordinary proteins that sometimes "go wrong", resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA. And the diseases they bring are now spreading around the world.
In The Family That Couldn't Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion's hidden past and deadly future. Through exclusive interviews and original archival research, Max explains this story's connection to human greed and ambition, from the Prussian chemist Justus von Liebig, who made cattle meatier by feeding them the flesh of other cows, to New Guinean natives whose custom of eating the brains of the dead nearly wiped them out.
The biologists who have investigated these afflictions are just as extraordinary. They include Daniel Carleton Gajdusek, a self-described "pedagogic pedophiliac pediatrician" who cracked kuru and won the Nobel Prize, and another Nobel winner, Stanley Prusiner, a driven, feared self-promoter who identified the key protein that revolutionized prion study.
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"Very timely and compellingly written." (Booklist)
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- A Biography of Polio
- By: Forrest Maready
- Narrated by: Forrest Maready
- Length: 5 hrs and 54 mins
- Unabridged
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A fascinating account of the world’s most famous disease - polio - told as you have never heard it before. Epidemics of paralysis began to rage in the early 1900s, seemingly out of nowhere. Doctors, parents, and health officials were at a loss to explain why this formerly unheard-of disease began paralyzing so many children. Why did this disease start to become such a horrible problem during the late 1800s? Why did it affect children more often than adults? Why was it originally called teething paralysis by mothers and their doctors?
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Root Cause
- By Circlekay1 Gulfport MS on 10-24-19
By: Forrest Maready
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The Pandemic Century
- One Hundred Years of Panic, Hysteria, and Hubris
- By: Mark Honigsbaum
- Narrated by: John Lee
- Length: 13 hrs and 40 mins
- Unabridged
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Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 "parrot fever" pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.
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Pretty good
- By Baz 12345 on 04-03-20
By: Mark Honigsbaum
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
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Pale Rider
- The Spanish Flu of 1918 and How It Changed the World
- By: Laura Spinney
- Narrated by: Paul Hodgson
- Length: 10 hrs and 4 mins
- Unabridged
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In this gripping narrative history, Laura Spinney traces the overlooked pandemic to reveal how the virus travelled across the globe, exposing mankind's vulnerability and putting our ingenuity to the test. As socially significant as both world wars, the Spanish flu dramatically disrupted - and often permanently altered - global politics, race relations, and family structures while spurring innovation in medicine, religion, and the arts.
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A Predilection for Those in the Prime of Life
- By Cynthia on 02-12-18
By: Laura Spinney
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Polio
- An American Story
- By: David M. Oshinsky
- Narrated by: Jonathan Hogan
- Length: 14 hrs and 37 mins
- Unabridged
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This comprehensive and gripping narrative, which received the 2006 Pulitzer Prize for history, covers all the challenges, characters, and controversies in America's relentless struggle against polio. Funded by philanthropy and grassroots contributions, Salk's killed-virus vaccine (1954) and Sabin's live-virus vaccine (1961) began to eradicate this dreaded disease.
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Wonderful
- By Patricia B Tripoli on 07-22-08
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Asleep
- The Forgotten Epidemic That Became Medicine’s Greatest Mystery
- By: Molly Caldwell Crosby
- Narrated by: Christian Rummel
- Length: 6 hrs and 31 mins
- Unabridged
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Overall
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Performance
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Story
In 1918, a world war raged, and a lethal strain of influenza circled the globe. In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it spread worldwide, leaving millions dead or locked in institutions. Then, in 1927, it disappeared as suddenly as it had arrived. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and asylums as they try to solve this epidemic and treat its victims - who learned the worst fate was not dying of it, but surviving it.
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Scary, and still unsolved, medical mystery
- By joyce on 12-14-14
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The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
- By: George Johnson
- Narrated by: Arthur Morey
- Length: 8 hrs and 19 mins
- Unabridged
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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
- By Digital Dilema on 09-06-13
By: George Johnson
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The Fantastic Laboratory of Dr. Weigl
- How Two Brave Scientists Battled Typhus and Sabotaged the Nazis
- By: Arthur Allen
- Narrated by: Dennis Holland
- Length: 10 hrs and 27 mins
- Unabridged
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Few diseases are more gruesome than typhus. Transmitted by body lice, it afflicts the dispossessed - refugees, soldiers, and ghettoized peoples - causing hallucinations, terrible headaches, boiling fever, and often death. The disease plagued the German army on the Eastern Front and left the Reich desperate for a vaccine. For this they turned to the brilliant and eccentric Polish zoologist Rudolf Weigl.
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An Unforgettable book
- By Jean on 09-01-14
By: Arthur Allen
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Influenza
- The Hundred-Year Hunt to Cure the 1918 Spanish Flu Pandemic
- By: Dr. Jeremy Brown
- Narrated by: Holter Graham
- Length: 6 hrs and 28 mins
- Unabridged
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On the 100th anniversary of the devastating pandemic of 1918, Jeremy Brown, a veteran ER doctor, explores the troubling, terrifying, and complex history of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for the next epidemic, should you get a flu shot, and how close are we to finding a cure?
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Important read
- By Kathryn C. on 12-21-18
By: Dr. Jeremy Brown
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Cannibalism
- By: Bill Schutt
- Narrated by: Tom Perkins
- Length: 8 hrs and 56 mins
- Unabridged
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Eating one's own kind is a completely natural behavior in thousands of species, including humans. Throughout history we have engaged in cannibalism for reasons related to famine, burial rites, and medicine. Cannibalism has also been used as a form of terrorism and as the ultimate expression of filial piety. With unexpected wit and a wealth of knowledge, Bill Schutt takes us on a tour of the field, exploring exciting new avenues of research and investigating questions like why so many fish eat their offspring and some amphibians consume their mothers' skin.
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Ruined it at the end
- By Kimberly Ames on 12-07-17
By: Bill Schutt
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p53: The Gene That Cracked the Cancer Code
- By: Sue Armstrong
- Narrated by: Elizabeth Jasicki
- Length: 9 hrs and 55 mins
- Unabridged
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p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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Excellent story! Unfortunate narration at start
- By Adriana on 12-25-14
By: Sue Armstrong
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Great Book, Great Narration, But...
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Ruined it at the end
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Now published in five languages, Strange Medicine casts a gimlet eye on the practice of medicine through the ages that highlights the most dubious ideas, bizarre treatments, and biggest blunders. From bad science and oafish behavior to stomach-turning procedures that hurt more than helped, Strange Medicine presents strange but true facts and an honor roll of doctors, scientists, and dreamers who inadvertently turned the clock of medicine backward.
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Great Book, Great Narration, But...
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Ruined it at the end
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From the masters of storytelling-meets-science, Patient Zero tells the long and fascinating history of disease outbreaks—how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us. Written in the authors’ lively style, chapters include gripping medical stories about a particular disease or virus—smallpox, Bubonic plague, polio, HIV—that combine “Patient Zero” narratives, or the human stories behind outbreaks, with historical examinations of missteps, milestones, scientific theories, and more.
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What won't we try in our quest for perfect health, beauty, and the fountain of youth? Well, just imagine a time when doctors prescribed morphine for crying infants. When liquefied gold was touted as immortality in a glass. And when strychnine - yes, that strychnine, the one used in rat poison - was dosed like Viagra. Looking back with fascination, horror, and not a little dash of dark, knowing humor, Quackery recounts the lively, at times unbelievable, history of medical misfires and malpractices.
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In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.
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Not one boring moment!
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The Clot Thickens
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This is a 150-year detective story with a cast of unrecognized heroes who may, finally, become known for their work on the true causes of heart disease. Exploring the truth about cholesterol—the apparently tried, and convicted, cause of millions of deaths from heart disease—with billions spent each year on lowering cholesterol with diet and drugs.
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Seriously the best book I read in 2022!
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Brain on Fire
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When 24-year-old Susannah Cahalan woke up alone in a hospital room, strapped to her bed and unable to move or speak, she had no memory of how she’d gotten there. Days earlier, she had been on the threshold of a new, adult life: At the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?
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A must read for anyone in the medical field, and anyone who has ever gone undiagnosed.
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10% Human
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You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony. Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.
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Must read for anyone that wants to be healthy
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What listeners say about The Family That Couldn't Sleep
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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Overall
- Tammy
- 03-02-07
Great book
Any one with a family member with a disability that is neurological in origin will appreciate this book. The author's final chapter says it all. Great narrator.
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5 people found this helpful
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Overall
- Kelly
- 08-31-07
A pleasure to hear
This book is a wonderful piece for people interested in the medical field. It offers a wonderfully accessible explanation of prion diseases combined with a human touch and a fabulous narrator voice. Highly recommended!
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5 people found this helpful
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- ANDRÉ
- 06-29-12
Interesting, scary
I learned a lot of prion from this book. The story is good and the writer tries to entangle the other kinds of prion disease. It's not just about the family that couldn't sleep. I hope that there will be a cure for prions soon.
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- K. Jane
- 02-19-19
Very Interesting
Well written story that delves into a topic that I had seen only in headlines and brief descriptions. This book dives into the history and scientific understanding of prions. I would highly recommend this book.
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- David
- 11-04-06
A great scientific mystery
This has become one of my favorite non-fiction books on audible. If you enjoyed "Splendid Solution", "The Great Influenza" or "Germs" you will love this one. It may not have the humor or entertainment value of "The Omnivore's Delimma" but the author does a fine job of weaving personal stories with science to create a fascinating story. This is a great introduction to Mad Cow and other prion diseases, and also provides a distrubing account of how governments bumble their way through such outbreaks.
Grover Gardner also performs another excellent reading. In my opinion, Gardner is by far the top narrator for any material that has any scientific or technical content. His voice moves gracefully over the text - always with the right nuance and pronunciation - allowing the listener to become quite captivated by the story.
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17 people found this helpful
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- Pam James
- 08-24-13
Prion Drama
It is surprising how fascinating a medical mystery can be. I was hanging on every word. I was terrified, but still could not stop listening.
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2 people found this helpful
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Overall
- Caryl
- 05-07-10
Wow a whole new issue to be aware of
Sneaky the way this author gets us into the world of virus disease, but persuasive.
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- Joaquin
- 01-14-22
fascinating book.
It is so intriguing. this book perfectly ties everything together to explain different people around the world throughout history to explain prions. I wanted to keep listening. I thoroughly enjoyed it.
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- ashley shannon
- 01-24-24
Very interesting!!!
Who doesn't love a great prison disease adventure! Was thoroughly engaged throughout, and would definitely recommend to laypeople interested in medical mysteries. The author is delightful, and Grover Gardner knocks it out of the park with his narration (as always, he's such a treasure <3)
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- Mary
- 06-09-12
Zombie science
I picked this right after starting the short-story anthology Zombies vs. Unicorns (zombie fiction sometimes blames prions) on Kindle. Fun connection. As to this book, it was a great story, interesting science, kept a good pace, and gave me pause (yet again) about eating factory-farm meat...
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2 people found this helpful