• 10 - Neo & colon

  • Jul 26 2024
  • Length: 4 mins
  • Podcast

  • Summary

  • Sulle riviste più importanti e ai congressi internazionali troviamo i risultati della applicazione di immunoterapia neoadiuvante in casi di carcinoma colorettale dMMR (mismatch repair–deficient). I risultati - in termini di risposte patologiche complete - sono semplicemente impressionanti.

    Bibliografia
    • Yu JH, et al. Neoadjuvant camrelizumab plus apatinib for locally advanced microsatellite instability-high or mismatch repair deficient colorectal cancer (NEOCAP): a single-arm, open label, phase 2 study. Lancet Oncol 2024; 25: 843–852.

    • Cercek A. Neoadjuvant Treatment of Mismatch Repair-Deficient Colon Cancer - Clinically Meaningful? N Engl J Med 2024; 390: 2024-2025.

    • Chalabi M, et al. Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair–Deficient Colon Cancer. N Engl J Med 2024; 390: 1949-1958.
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