Episodios

  • Why Syncing Atomic Clocks is Virtually Impossible | Judah Levine on UTC
    Nov 26 2025

    Why is syncing atomic clocks still one of the hardest problems in physics and engineering?

    In this episode, we speak with Judah Levine—legendary NIST physicist and one of the key architects of modern timekeeping—about the invisible systems that hold the digital world together. Levine explains why synchronizing atomic clocks across the planet is far more complex than the clocks themselves, and why seemingly simple ideas like “round-trip delay” break down in real-world media such as fiber optics and the internet.

    We explore how UTC is built from hundreds of atomic clocks, the difference between keeping time and *transferring* time, and the surprising challenges introduced by asymmetric delays, chromatic dispersion, and environmental noise. Levine walks us through the evolution of cesium clocks, the rise of optical clocks, and the technologies that make GPS, finance, power grids, and global communication possible.

    Along the way, we discuss the history of time synchronization, from railroad schedules to radio frequencies to modern satellite systems; the ongoing debate over leap seconds; and why the future of precision timing depends not just on better clocks, but on better *engineering* to deliver those clocks’ performance to the real world.

    Whether you’re curious about atomic clocks, relativity, fiber optics, GPS, the structure of time itself, or the hidden physics behind everyday technology, this conversation offers a rare look at how science, engineering, and careful statistical thinking keep modern civilization in sync—down to the nanosecond.

    Follow us for more technical interviews with the world’s greatest scientists:

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    Follow our hosts!
    Michael Dubrovsky: https://x.com/MikeDubrovsky
    Misha Shalaginov: https://x.com/MYShalaginov
    Xinghui Yin: https://x.com/XinghuiYin

    Subscribe:
    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR
    Website: [https://www.632nm.com](https://www.632nm.com/)

    Timestamps:
    00:00 – Intro
    01:03 – What is UTC?
    05:50 – Timekeeping for Satellites
    07:08 – How Radio Created Better Clocks
    18:32 – From Astronomy to Atoms
    25:25 – Why are there 24 Hours in a Day?
    29:55 – Why Synchronizing Clocks is so Hard
    47:09 – How did Judah get into Clocks?
    53:29 – Is UTC Vulnerable to Hackers?
    1:06:41 – Cesium vs Optical Atomic Clocks
    1:11:23 – How Cesium Clocks Work
    1:23:35 – Why Cesium Clocks are Imperfect
    1:26:17 – Judah’s 3 Year Experiment
    1:29:30 – Statistics with Clocks
    1:33:40 – Is Time Real?
    1:36:29 – Is the Universe Slowing Down?
    1:40:29 – Atomic Time and General Relativity
    1:42:17 – What’s Left for Atomic Clocks?
    1:54:34 – What would Judah do with Unlimited Funding?
    1:58:57 – Judah's Past in Programming
    2:02:55 – Advice for Young Scientists

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    2 h y 4 m
  • Can We Predict History Like the Weather? | Peter Turchin on Cliodynamics
    Nov 4 2025

    Why do civilizations rise, prosper, and then collapse? Here's what the math tells us.

    In this episode, we sit down with Peter Turchin, complexity scientist and founder of the field of cliodynamics, which uses data and mathematical models to study the long-term cycles of history. Turchin explains his theory of elite overproduction, how societies generate too many ambitious, educated elites competing for too few positions, and why this dynamic reliably leads to polarization, inequality, and political turmoil.

    We explore how his structural-demographic theory maps the recurring “boom and bust” rhythms that have shaped civilizations from ancient Rome to modern America, the role of military competition in driving cooperation and social complexity, and how new tools—from AI-assisted historical databases to ancient DNA and LiDAR—are transforming the study of the past.

    Whether you’re drawn to history, sociology, complexity science, or the fate of modern democracies, this conversation reveals how Turchin’s quantitative approach offers a new way to understand—and maybe even forecast—the forces that make societies rise and fall.

    Follow us for more technical interviews with the world’s greatest scientists:

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    LinkedIn: https://www.linkedin.com/company/632nm/about/
    Substack: https://632nmpodcast.substack.com/

    Follow our hosts!
    Michael Dubrovsky: https://x.com/MikeDubrovsky
    Misha Shalaginov: https://x.com/MYShalaginov
    Xinghui Yin: https://x.com/XinghuiYin

    Subscribe:
    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR
    Website: https://www.632nm.com

    Timestamps:

    00:00 - Intro
    01:48 - Overproduction of Elites
    10:56 - Did Models Predict the Rise of Trump?
    20:43 - Is Russian History Repeating in the US?
    26:48 - How Competition Stabilizes Societies
    32:14 - What Data Goes into Cliodynamic Models?
    38:13 - How New Technologies Shaped Archaeology
    43:28 - Can Historians Build Mathematical Intuitions?
    47:59 - What Questions can be Answered with Cliodynamics?
    52:23 - Does the NYC Mayoral Race Fit into Turchin's Theory?
    56:37 - Is Fear of China Bringing Us Together?
    58:29 - Do Historians Reject Turchin’s Work?
    1:00:03 - Trends in Civilizations and Outliers
    1:03:29 - Calvary and the Evolution of Societies
    1:10:03 - Is Evolution via Natural Selection a Suitable Analog for History?
    1:15:16 - Could Turchin's Ideas Be Misinterpreted Dangerously?

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    1 h y 18 m
  • Why Do Quantum Computers Make So Many Mistakes? | Mikhail Lukin on Quantum Error Correction
    Oct 21 2025

    You can’t copy a qubit. So how do quantum computers remember anything?

    In this episode, we sit down with Mikhail Lukin, Harvard physicist and co-director of the Harvard Quantum Initiative, whose lab is building quantum computers from arrays of individually trapped atoms. Lukin explains the paradox of quantum error correction—how you can safeguard quantum information even though it can’t be copied or measured directly—and why this breakthrough may be the key to making large-scale quantum computers possible.

    We dive into the strange logic of superposition, entanglement, and “small cat states,” explore what makes quantum evolution inherently analog, and learn how Lukin’s team uses optical tweezers and Rydberg interactions to engineer stable, reconfigurable qubits—atoms literally held and moved by light.

    Whether you’re fascinated by quantum mechanics, computing, Schrödinger’s cat, or the future of information, this conversation reveals how physicists are turning the weirdness of quantum physics into working technology—and why building a fault-tolerant quantum computer is one of the hardest and most exciting challenges in science today.

    Follow us for more technical interviews with the world’s greatest scientists:
    Twitter: https://x.com/632nmPodcast
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    LinkedIn: https://www.linkedin.com/company/632nm/about/
    Substack: https://632nmpodcast.substack.com/

    Follow our hosts!
    Michael Dubrovsky: https://x.com/MikeDubrovsky
    Misha Shalaginov: https://x.com/MYShalaginov
    Xinghui Yin: https://x.com/XinghuiYin

    Subscribe:
    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR
    Website: https://www.632nm.com

    Timestamps:
    00:00 - Intro
    01:32 - Fundamentals of Quantum Computers
    04:09 - Transistors vs Quantum Gates
    10:07 - What is Quantum Error Correction?
    14:23 - State of the Art QEC
    22:19 - Quantum Research Before Lukin
    27:35 - Lukin’s Breakout Work
    31:10 - From Quantum Optics to Quantum Computing
    36:59 - Working with Neutral Atoms
    48:17 - Funding Quantum Computers
    50:00 - Transverse Gate Operations
    58:22 - Is Quantum Computing All Hype?

    #quantumcomputing #quantumerrorcorrection #mikhaillukin #qubits #schrodingerscat #entanglement #superposition #quantumphysics

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    1 h y 1 m
  • We Interviewed the Winners of the Ig Nobel Prize | Ig Nobel 2025
    Oct 9 2025

    The scientific stories behind this year's research that made people LAUGH, then THINK.

    Watch the 2025 Ig Nobel Ceremony here: https://youtu.be/z1cP4xKd_L4

    In this episode, we bring together three of this year’s Ig Nobel winners whose research spans psychology, food science and human biology. You’ll hear how a team of psychologists devised a counter-intuitive way to boost a narcissist’s self-confidence; how two physicists uncovered the “mozzarella phase” of pecorino cheese while perfecting cacio e pepe; and how a group studying lactation discovered that garlic changes breast-milk’s aroma and baby behavior.

    We explore the playful setups, surprising results and serious science behind each project, and how curiosity, humor and a dash of persistence turned ordinary questions into prize-winning research.

    Follow us for more technical interviews with the world’s greatest scientists:

    Twitter: https://x.com/632nmPodcast
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    LinkedIn: https://www.linkedin.com/company/632nm/about/
    Substack: https://632nmpodcast.substack.com/

    Follow our hosts!
    Michael Dubrovsky: https://x.com/MikeDubrovsky
    Misha Shalaginov: https://x.com/MYShalaginov
    Xinghui Yin: https://x.com/XinghuiYin

    Subscribe:
    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR
    Website: https://www.632nm.com

    Timestamps:
    00:00 - Intro
    01:19 - Physics Prize: Cacio e Pepe Sauce
    30:40 - Pediatrics Prize: Garlic Breast Milk
    44:48 - Psychology Prize: How to Boost Narcissism

    #ignobel2025 #cacioepepe #pastasauce #thermodynamics #psychology #dairy #pecorino

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    1 h y 6 m
  • What Science can Learn from Startups | Adam Marblestone on Focused Research Organizations
    Oct 7 2025

    Science has stalled. And Adam Marblestone thinks he knows why.

    Check out the Research Gap Map here: https://www.gap-map.org/?sort=rank

    In this episode, we sit down with Adam Marblestone, neuroscientist, nanotechnologist, and founder of Convergent Research, to explore how new “Focused Research Organizations” (FROs) could reignite scientific progress. From DNA “ticker-tape” neural recording to optical connectomics and Neuralink, Marblestone explains how emerging neurotechnologies reveal both the brilliance and the bottlenecks of today’s research system.

    We discuss why traditional funding often fails to support ambitious, interdisciplinary projects, how FROs borrow the focus and speed of startups to build scientific infrastructure, and why projects like OpenAI, E11 Bio, and ultrasound-on-a-chip exemplify this new model. Marblestone breaks down his “Gap Map” of unsolved scientific challenges - from room-temperature superconductors to artificial ribosomes - and does the math on how tens of billions of dollars could close them.

    Whether you’re fascinated by neuroscience, scientific innovation, or the future of research itself, this conversation offers a rare insider’s look at how new institutions could rebuild the engine of discovery—and why the next wave of breakthroughs might depend more on organization than on ideas.

    Follow us for more technical interviews with the world’s greatest scientists:
    Twitter: https://x.com/632nmPodcast
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    LinkedIn: https://www.linkedin.com/company/632nm/about/
    Substack: https://632nmpodcast.substack.com/

    Follow our hosts!
    Michael Dubrovsky: https://x.com/MikeDubrovsky
    Misha Shalaginov: https://x.com/MYShalaginov
    Xinghui Yin: https://x.com/XinghuiYin

    Subscribe:
    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR
    Website: https://www.632nm.com

    Timestamps:
    00:00 - Intro
    01:25 - Working with George Church
    13:03 - Neuralink
    22:23 - Gap Maps
    31:47 - Artificial Ribosome
    36:45 - What is Convergent Research?
    40:03 - What are FROs?
    44:16 - What Made OpenAI So Successful?
    48:19 - Has AI Actually Impacted Science?
    52:15 - Notable FROs
    1:05:43 - Why Haven't There Been More Scientific Breakthroughs?
    1:09:47 - Lithography and Chip Design
    1:13:41 - We Can't Beat Insects
    1:16:45 - What Separates Good FROs
    1:18:40 - East vs West Coast Innovation
    1:27:21 - Research into Longevity
    1:33:27 - Advice for Grad Students
    1:39:40 - How to Get Involved in FROs

    #neuroscience #molecularbiology #quantumphysics #researchfunding #startups

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    1 h y 41 m
  • What Optical Atomic Clocks Tell Us About Space-Time | Jun Ye
    Sep 23 2025

    Times have changed. And cesium clocks can't keep up.

    In this episode, we sit down with Jun Ye, Joint Institute for Laboratory Astrophysics (JILA) Fellow and pioneer of optical lattice clocks, whose work has pushed timekeeping far beyond traditional cesium atomic clocks. Ye explains how combining ultra-stable lasers, frequency combs, and ultra-cold atoms produces clocks more than 100× more precise than today’s standards: so sensitive they can detect gravitational time dilation across the width of a human hair.

    We explore how this next generation of atomic clocks may open windows onto gravitational waves, test Einstein’s relativity in new regimes, and even help build a GPS for space travel. Ye also shares his personal journey from growing up during China’s Cultural Revolution to becoming a leader in precision measurement, and what that experience taught him about resilience, mentorship, and protecting scientific inquiry.

    Whether you’re curious about time, relativity, quantum physics, GPS technology, or the frontiers of precision measurement, this conversation offers a rare insider’s look at how breakthroughs in timekeeping can lead to entirely new physics.

    Follow us for more technical interviews with the world’s greatest scientists:

    Twitter: https://x.com/632nmPodcast
    Instagram: https://www.instagram.com/632nmpodcast?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==
    LinkedIn: https://www.linkedin.com/company/632nm/about/
    Substack: https://632nmpodcast.substack.com/

    Follow our hosts!
    Michael Dubrovsky: https://x.com/MikeDubrovsky
    Misha Shalaginov: https://x.com/MYShalaginov
    Xinghui Yin: https://x.com/XinghuiYin

    Subscribe:
    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR
    Website: https://www.632nm.com

    Timestamps:

    00:00 - Intro
    01:17 - Why Haven't Optical Clocks Replaced Cesium Clocks?
    10:45 - Fundamentals of Optical Atomic Clocks
    17:34 - History of Atomic Clocks
    30:18 - What is JILA?
    35:01 - What brought Jun to JILA?
    39:33 - What does it take to get a PhD in Physics?
    42:40 - Jun Ye's PhD work
    44:36 - Limitations of Laser Stabilization
    50:38 - How Do We Make the Most Stable Lasers?
    57:28 - How to Measure Laser Coherence Times
    1:04:24 - Building Atomic Clocks from First Principles
    1:08:59 - Jun's Notable Accomplishments
    1:14:00 - Magic Frequencies for Optical Traps
    1:21:04 - Can AI Improve Atomic Clocks?
    1:24:00 - How Does Quantum Entanglement Affect Clocks?
    1:30:29 - Development of Quantum Computers
    1:34:23 - Pros and Cons of Nuclear Clocks
    1:43:49 - What Would Jun Do With Unlimited Research Funding?
    1:47:09 - Lessons from China's Cultural Revolution

    #quantumcomputing #quantumphysics #atomicclock #laser #physics #optics #astrophysics #astronomy #spacetime

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    1 h y 53 m
  • Laser Cooling and Quantum Timekeeping | Bill Phillips
    Sep 9 2025

    How did cooling atoms with lasers revolutionize our understanding of time?

    In this episode, we speak with Bill Phillips, Nobel Laureate in Physics, about his groundbreaking work on laser cooling and trapping of atoms: research that not only won him the Nobel Prize but also transformed modern timekeeping and technology. Phillips explains why breaking the Doppler cooling limit changed physics forever and what it means that today’s clocks can measure time differences caused by moving a device just a few millimeters in Earth’s gravity.

    We discuss the history of timekeeping from sundials to atomic clocks, how Einstein’s relativity reshaped our view of time, and the serendipitous discovery of sub-Doppler cooling that opened the door to ultra-precise measurement, quantum computing, and fundamental tests of nature. Along the way, Phillips reflects on the culture of physics, the importance of mentorship, and the joy of discovery.

    Whether you’re curious about time, relativity, quantum physics, GPS technology, or the frontiers of precision measurement, this conversation offers rare insight into how science, collaboration, and curiosity converge to shape the modern world.

    Follow us for more technical interviews with the world’s greatest scientists:

    Twitter: https://x.com/632nmPodcast
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    LinkedIn: https://www.linkedin.com/company/632nm/about/
    Substack: https://632nmpodcast.substack.com/

    Follow our hosts!

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    Misha Shalaginov: https://x.com/MYShalaginov
    Xinghui Yin: https://x.com/XinghuiYin

    Subscribe:

    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR
    Website: [https://www.632nm.com](https://www.632nm.com/)

    Timestamps:
    00:00 - Intro
    01:43 - What is Time?
    05:49 - How Did Bill Get Into Atom Cooling?
    18:30 - How Do Atomic Clocks Actually Work?
    31:08 - History of Atomic Clocks
    37:18 - Laser Cooling for Atomic Clocks
    40:49 - How To Synchronize Atomic Clocks
    43:20 - How Cesium Cooling Was Developed
    45:48 - Pushing Beyond the Doppler Limit
    49:47 - The Beginning of Thor Labs
    52:45 - The Previous Limits were Wrong
    1:05:37 - How Bill Broke the Doppler Limit
    1:12:22 - What is Optical Pumping?
    1:20:27 - Can Atom Trapping Be Leveraged For Cold Fusion?
    1:31:32 - What Makes Bill So Lucky?
    1:35:25 - How Bill's Work Led to Atomic Clocks
    1:41:05 - What Makes Cesium So Good For Atomic Clocks?
    1:47:38 - Quantum Effects on Atomic Clocks
    1:59:02 - Bose-Einstein Condensates
    2:09:05 - Did Bill's Work Lead To Quantum Computing?
    2:11:26 - Bill's Thoughts on the Future

    #billphillips #nobelprize #laser #atomicclock #dopplereffect #quantumcomputing #quantumphysics #gps #physics #boseeinsteincondensate #theoreticalphysics #relativity

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    2 h y 24 m
  • Inside the Battle for Psychedelic Therapy | Rick Doblin
    Aug 26 2025

    What does it take to turn a banned psychedelic into an FDA-approved medicine?

    Visit MAPS to read about the latest progress is psychedelic research: https://maps.org/

    In this episode, we speak with Rick Doblin, founder of the Multidisciplinary Association for Psychedelic Studies (MAPS), about the decades-long mission to make MDMA-assisted therapy a legal treatment for PTSD and other mental health conditions. Rick received his PhD from Harvard's Kennedy School of Government in public policy focusing on the regulation of medical use of psychedelics in 2001. Rick shares the science behind MDMA’s therapeutic effects, the strategy for winning over regulators, and the battles over claims of neurotoxicity. We discuss the history of psychedelic research, the rise of the underground therapy movement, and how clinical trials, policy change, and cultural perception must align to move psychedelics from stigma to science.

    Whether you’re curious about psychedelic science, drug policy reform, FDA clinical trials, or the future of mental health treatment, this conversation delivers expert insight into the intersection of research, regulation, and real-world impact.

    Follow us for more technical interviews with the world’s greatest scientists:

    Twitter: https://x.com/632nmPodcast
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    LinkedIn: https://www.linkedin.com/company/632nm/about/
    Substack: https://632nmpodcast.substack.com/

    Follow our hosts!

    Michael Dubrovsky: https://x.com/MikeDubrovsky
    Misha Shalaginov: https://x.com/MYShalaginov
    Xinghui Yin: https://x.com/XinghuiYin

    Subscribe:
    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR
    Website: [https://www.632nm.com](https://www.632nm.com/)

    Timestamps:

    00:00 - Intro
    01:32 - How Would Rick Describe a Psychedelic Experience?
    05:02 - What is Rick's Favorite Psychedelic?
    09:46 - The Underground is Ahead of the Research
    12:45 - How Rick Got Interested in Psychedelics
    26:39 - Can Psychedelics Stop War?
    40:45 - Do People Need Trauma?
    45:09 - Is America a Falling Empire?
    52:08 - What if MAPS was in the YC?
    55:00 - Why was MDMA the Choice to Push for Legality?
    1:02:22 - The Origins of Modern Psychedelic Therapy
    1:05:20 - Misinformation Around Psychedelics
    1:17:12 - How MAPS is Developing Psychedelic Therapies
    1:30:13 - How Should Healthy People Use Psychedelics?
    1:38:05 - Psychedelic Experiences as Rites of Passage
    1:42:02 - Finding Life's Purpose
    1:52:49 - Why Do Fears of Psychedelics Persist?
    1:56:44 - What Does It Take for Psychedelics to Get FDA Approved?
    2:13:55 - Rick's Pet Wolf
    2:23:39 - Rick's Last Interaction with his Wolf
    2:30:55 - Psychedelic Group Therapy
    2:33:37 - We Need More Psychedelic Therapists

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    2 h y 38 m