• Age Reversal 2: NMN & NR, Metformin and Rapamycin -The Hype, The Choke and The Protector

  • Jan 31 2024
  • Length: 21 mins
  • Podcast

Age Reversal 2: NMN & NR, Metformin and Rapamycin -The Hype, The Choke and The Protector By cover art

Age Reversal 2: NMN & NR, Metformin and Rapamycin -The Hype, The Choke and The Protector

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  • Summary

  • Another juicy installment in our age reversal series. Today we are talking about the science behind some of the most popular age reversal trends and trials. Here are some quick links to the studies mentioned in the video & for more information

    The first human clinical study for NMN has started in Japan Kazuo Tsubota: https://www.nature.com/articles/npjamd201621

    Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms Sheng Chen:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965502/

    Effects of putative metformin targets on phenotypic age and leukocyte telomere length: a mendelian randomisation study using data from the UK Biobank Shan Luo, PhD :
    https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(23)00085-5/fulltext

    Rapamycin, the only drug that has been consistently demonstrated to increase mammalian longevity. An update, Author links open overlay panelZelton Dave Sharp:
    https://www.sciencedirect.com/science/article/pii/S0531556523000876
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