Episodios

  • [EP.17]Mastering Your Genetic Code for Optimal Health: Dr. Bob Miller’s Latest Insights

    [EP.17]Mastering Your Genetic Code for Optimal Health: Dr. Bob Miller’s Latest Insights
    Jun 19 2024
    Dr. Joel Rosen:I would like to welcome Bayou Ck. I believe this is our third interview with Bob. Yeah, he is a traditional naturopath specializing in the field of genetics-specific nutrition. Bob is also an educator. He lectures nationally and internationally at seminars to educate health practitioners about genetic variants and nutritional supplementation for obtaining optimal health. Bob is also a researcher. He’s expanding his genetic research efforts. He founded and personally funded the NutriGenetic Research Institute to study the relationship between genetic variants and presenting symptoms. He’s also a nutritional supplement formulator and a genetic analysis software creator. Bob here is going to help us learn about cracking the code. So, Bob, welcome once again to another edition of helping people get their health back. Dr. Bob Miller:Oh, it was a pleasure to be with you. It’s um, I always enjoy these interviews because we’ve, we always have a good time, we kind of geek out a little bit on some of the deep dives on biochemistry, and it was a lot of fun. So yeah, do the same thing today. Dr. Joel Rosen:Excellent. So okay, so Bob, go ahead and share your screen and give our listeners what’s the latest and greatest, in what you’re researching. Dr. Bob Miller:Already? Well, our subject today is going to be superoxide. Now, you know, the traditional naturopathic philosophy has always been that most problems we see come from inflammation, from excess free radicals. We’ve been on that path for all of our time working: what is creating extra free radicals, and then what is causing us to not be able to break those free radicals down. Now, on the other hand, free radicals are bad if they’re in excess, but they can be our friend. One of my favorite sayings has been, you know, they can be your friend unless they’re not. So we need free radicals to kill viruses and bacteria. And even if we have bad cells inside the body, we need inflammation to kill them. But on the other hand, if it goes to the extreme, that’s when we have a problem. So we tend to villainize free radicals, and rightfully so. But on the other hand, we have to be careful that we don’t eradicate all free radicals, that they do play a role for us. Our subject again is superoxide. And again, we always mention that we’re not treating any disease here. This is for educational purposes only and informational. So our learning objectives today are what superoxides, and random superoxide, and then we’re going to delve into how excess superoxide impacts. We’re going to look at pathways of how we make superoxide and pathways of how we reduce it. And then we’re going to dig into something called ferroptosis, where superoxide causes iron to do some really bad things. So, you’ll see here it’s all about balance. Superoxide plays a role in the body at times, but in excess, it can cause all kinds of problems for us. Now, this little chart here that you see. You’ll see on the left there it says oxygen o2 and unfortunately, that too got knocked off. But as you know, oxygen is o2. So what you’re seeing and by the way, do you see my little love? Okay, good. So the oxygen is two oxygen atoms, and you see these two little dots there. That’s electrons. So we all remember even from high school that, you know, you’ve got the neutron-proton and the electron, and they need to be paired. So here’s two together, here’s two together, here’s two together, they’re all paired up. This superoxide occurs when an extra electron comes on here that shouldn’t be there, and that makes it very unstable. And I’m going to show you in a little bit why this can be the root cause of a lot of our problems. Now, the body is pretty amazing. There are multiple ways here, but I’m going to show you one of the main ways. There’s an enzyme called superoxide dismutase. Number two, so this is superoxide. Dismutase means to break it down. And it takes the mineral manganese, not magnesium, manganese. And I’ll show you a better chart later, but it turns it into oxygen. But it also turns it into hydrogen peroxide. And hydrogen peroxide again, is not all bad. Sometimes we use hydrogen peroxide to kill pathogens. But if we have too much of it and we have dysregulated iron, we’ll make what are called hydroxyl radicals that damage the DNA and just wreak havoc throughout the body. However, we do have other mechanisms. If we have enough catalase, that’ll turn that hydrogen peroxide into water and oxygen. And there’s something called glutathione that we’ll dig into a little bit later. And there’s an enzyme called glutathione peroxidase that takes that glutathione and turns it into two water molecules. So there’s a lot that can go wrong here; we can overproduce superoxide. We’re going to show you how you can have less than optimal production, less than optimal catalase glutathione, where you can have iron dysregulation. So this is a ...
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    Menos de 1 minuto
  • [EP.16]Enzyme Secrets Unlocking the Key to a Longer, Healthier Life

    [EP.16]Enzyme Secrets Unlocking the Key to a Longer, Healthier Life
    May 1 2024
    Dr. Joel Rosen:All right, so today I’m joined by Jeff Owen. He has been an ASD enzyme US retail private label practitioner educator trainer since 2021. He’s worked in the natural industry for over three decades and I’m really interested to know Ask him about his experiences. And he represented a number of large supplement supplement manufacturers. And I told Jeff before we get started, we’d want to hear about sort of The Good, the Bad, and the Ugly if he’s willing to tell us about all that. But without further ado, Jeff, thank you so much for being here today. Jeff Owen:Dr. Rosen, thank you so much for having me as your guest. I really feel privileged. Oh, good. Well, listen, Dr. Joel Rosen:I’ve had some guests in the past where their same position as you and I, and I’m always interested to hear about your experiences, and most importantly, what the listener can glean from that to help their own health journey and feel younger at heart and younger physically, mentally, emotionally. So Jeff, what tell me just give us sort of an overview of, why you got into this industry, you were telling me you have a sort of a unique background in your health journey. Jeff Owen:So in terms, in terms of the chronology, of how the company makes the enzyme and probiotic products, the raw materials themselves were made in Mumbai, India, and then they’re shipped to Chino, California, where there are four NS-certified manufacturing facilities, the first of which opened in 1985. And as you can imagine, what our company is committed to is rigorous rigorous testing. So the products are tested, tested, tested, and set at a GMP-certified facility. And then the fermentation, the extraction, the blending, the formulating all that is done at in Chino, California. And what I like about this company, Dr. Rosen is that they’re not trying to be all things to all people. In other words, this company, their, their, the mission of this company, is to be a pre-eminent science manufacturing company. And of course, the challenge for any company that’s involved with nutritional manufacturing, supply manufacturing, is to get the science, if you will, the pure science and apply it, you know, commercially, if you will, so that they’re linked together. And they were aligned. And I feel like of all the companies that I’ve had the opportunity to work with, in 30 plus years in the natural products industry, this company does it as well as anybody. Dr. Joel Rosen:Yeah, well, there, you said a lot there, which is, which is interesting. So a couple of things that I would want to touch upon is obviously enzymology. And that’s the purpose of our call today, and what that is and what enzymes are and how they differ from digestive purposes and systemic, like breaking down the purposes which we’ll get to in a second, I have seen that I’ve had another interview with the guests and talking about how some of these companies that were privately got sold to pharmaceutical companies and the concern with the I guess the goal of the company, does it change in terms of providing the best quality or are they trying to cut corners and get the cheapest product and make a higher profit. Also, the concern is that he did the other guests talked about how you get a trade-off, you can be darn sure that the the cleanliness of the lab and making sure that they are getting quality control in there is going to be top-notch, but at the same time is the products going to be top notch. So thank you for sharing your insight with your new company. Just before we get into the enzymes, and what they are one of the questions I like to ask guests is that we talk about supplements and the the purity of their products and the the emphasis that goes into the quality right from sourcing it themselves. I had the privilege of going through a lab and I liked that they teach this or they emphasize this to their sales reps because they need to know that their quality of the product that they’re representing is of the highest quality so that you feel good about what you’re promoting to other people. So with that being said, I had a chance to walk through a lab that is a supplement company that does the same thing or has the same emphasis. I guess the question to you Jeff is the they use the what’s the name of the just last off the top of my head but they will it is a way that they scan the products to fo photometry or how they Jeff Owen:Go to liquid chromatography or HPLC. Yes. Dr. Joel Rosen:So thank you. So maybe I’m sure they use that to tell our listeners what that is and how that’s able to discern the quality of the product with purities, or impurities if that’s being used or not, or also with another concern that I typically have is they’ll use a lot of flow through agents that will have some excipients in there that are told, Well, it’s not that much of a problem, or you shouldn’t worry about it, but in the reality is, if you’re ...
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    58 m
  • [EP.15]TOXIC SUPERFOODS With Sally K Norton MPH

    [EP.15]TOXIC SUPERFOODS With Sally K Norton MPH
    Mar 27 2024
    Dr. Joel Rosen:Right Hello, everyone, and welcome back to another edition of the age-reversing blueprint podcast. And I’m excited to talk to our next guest. She is Sally Norton, who is an Ivy League nutritionist and author of her new book Toxic Superfoods How Opposite Overload Is Making You Sick, and How to Get Better. Today we will be talking about genetic testing oxalates and identifying foods that may be making you worse or better. And ultimately, in the overall clinical picture, Sally recovered from her health issues by lowering her oxygen intake and burden. And she’s here to talk to us about that today. So thank you so much for being here today, Sally. Sally K. Norton, MPH:Thanks for having me. You’re gonna enjoy it. Dr. Joel Rosen:So yeah, we were talking a little bit beforehand before we got started. And but I always like to ask my guests you know, tell us your story. Because your story is usually yours is why you’re doing what you’re doing. So maybe give us the listeners a little bit about what you’re dealing with I know, when you were younger you were planting a farmer. And you’re, I’ve heard some of the stuff that you’ve talked about in the past. So maybe take us through a cliff notes version of your health challenges. Sally K. Norton, MPH:Well, I got committed to learning about what I teach and what I’ve written about with the book. Because when I did finally figure out what had been dogging my health since I was a kid, particularly at age 12, but probably very much earlier in life. You know, I was 49, about to turn 50 When I figured this out. And, because in my career, I’ve worked in medical schools, multiple ones, and been in the public health field my entire life. And I had all these great connections with doctors who do integrative medicine, functional medicine, all the complementary and alternative therapists, I’ve seen them all, I’ve spent tons of money on it, and no one can help me. I couldn’t help myself, I have a degree from Cornell Nutrition and a public health degree from a major Institute here in the US. And nobody could help me. Despite my, you know, affluence of connections, and knowledge and information, I was ignorant, and we all were ignorant about what was messing up my health. And I realized that I couldn’t be the only person who was sick because of sweet potatoes, swiss chard, and healthy eating, which is ultimately what I found out, which is heartbreaking. Because yeah, I have this big organic garden. And a lifetime of being a goody two shoes at the dinner table, to you know, my siblings didn’t like that I was a bad example at the table who would eat her vegetables. You know, so it’s all worked against me doing the right thing. And it turns out that many other people have this problem of being sick because of stuff that we eat all the time that we think is fine to eat. And that’s a pretty shocking message to run into. Luckily, I live long enough to figure it out. But it takes a while to recover from it. So where I am now with my health is I no longer have the arthritis, but I no longer have a uterus or ovaries. I mean, you lose things along the way of being sick and not knowing why I still have back problems. I have all kinds of problems in my spine, which include pits and holes and the bones and stenosis and, bone spurs and for set joint arthritis up and down, very flattened and bulging discs, all kinds of degeneration of the tissues in here and year 11. I’ve started my 11th year without a high oxalate diet, I feel like my body’s still working on and proof spine, how much of that tissue can recover? I don’t know. Eating a high oxalate diet causes calcifications and fascia and connective tissue, it turns on all kinds of genetic weirdnesses in the body where suddenly perfectly innocent cells become aberrant cells and you get this calcification and so on. So, you know, a lifetime of healthy eating led to a lot of oxidative stress, connective tissue damage, hormonal damage, thyroid damage, brain damage, digestive problems, rheumatoid rheumatism, and so on. So I had the whole gamut. For the most part, I spent years in crutches and wheelchairs, I had to leave Cornell for four years of medical leave because my feet were so bad. And it was after I changed my diet at age 49, that my feet finally started working. Dr. Joel Rosen:Well, yeah, you know, and it’s you met going back to having the wealth of practitioners and competent people around, you would suggest that it’s new, and relatively for myself speaking oxalates up until maybe 656 years ago, was like, what is that? But the research goes back, you know, 100 years, maybe talk about the early research that shed light on what oxalates are and how deleterious they are, and maybe give us an idea as to why you think it’s usually it’s 17 years behind the research before the field generals catch up with the ivory towers, but we’re talking about hundreds of years. So at least 100...
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    58 m
  • [EP.14] Why Omega 3 Accomplishes Longevity & Why Omega 6 isn’t the Almighty Devil?

    [EP.14] Why Omega 3 Accomplishes Longevity & Why Omega 6 isn’t the Almighty Devil?
    Jan 3 2024
    Dr. Joel Rosen:Hey guys, welcome back to another edition where I’m excited to announce our amazing guest Dr. Bill Harris as he’s been a leader and leading researcher in the omega-3 three fatty acid field for over 40 years. He has over 300 scientific papers on fatty acids and health, the vast majority on omega threes. He has been on the faculty of three medical schools and has received five NIH grants to study omega threes. He was the co-author of three h A statements on fatty acid and heart health as the CO inventor of the Omega three index, which we’ll be getting into, and the Omega three blood tests and founder of mega quant analytics, Dr. Harris has been ranked among the top 2% of scientists worldwide based on the impact that he’s had with his research. Dr. Bill, thank you so much for being here today. Dr. Bill Harris:Great to be here. Yes. Dr. Joel Rosen:So I always like to do some research so that I can ask intelligent questions before we get here. I know that initially in the 70s, you were asked to study dietary fat and its effects on cholesterol. At that time, we knew that animal fats raised cholesterol, or at least now we know triglycerides and vegetable oils lowered cholesterol or triglycerides. But as you mentioned there we weren’t sure why. So potentially over the 40 years, I guess that’s a good starting point to know where we started from and where we are now. You know. Dr. Bill Harris:And so do we know why liquid oils, lower cholesterol, and saturated fats raise cholesterol? I think we know better. I think we know now that you’re changing membrane fatty acid composition with the different fats that we’re eating. and a high saturated fat diet does change the the way that the liver and liver cells process or remove LDL cholesterol LDL particles from the blood that’s of course, that’s the way statins work they upregulate the LDL receptors and remove more LDL from the blood. And if you’re getting more saturated fat versus polyunsaturated fat, those LDL receptors are not as efficient at moving LDL out of circulation. So LDL levels go up. That’s kind of shorthand of what we know now but there is a physical selling biochemical reason for why different fats have different effects on cholesterol outs. Dr. Joel Rosen:Okay, great. So So then as far as springing forward from that we know so much about the Omega threes and the longevity studies and why they’re so important for human health. Maybe we can get into that. Dr. Bill Harris:Sure. Yeah. We’ve been interested in, of course, Omega Three for a lot of time. And until now, I don’t know maybe 10 or 15 years ago, nobody looked at total mortality or effects. They’ve looked and looked at people with cardiovascular disease and the effects of Omega three on those people typically lower the risk for cardiovascular events, which should translate into a longer lifespan. You have fewer events. More recently we’ve been part of a group called Force fo RCE, which stands for Fatty Acid Outcomes Research Consortium, it’s a group that started at Tufts University in Boston. And it’s a collaboration of multiple individuals who have access to different research cohorts like the Framingham cohort, or like epic, or Mesa, or Eric, are these acronyms that we throw around the most people don’t know, but they’re fundamentally groups of people that have volunteered to be in a lifetime study. You know, like in Framingham, they took like 4000 people out of the town of Framingham, Massachusetts, in the 1940s, when they started, and they did every test known to man in on these people, they’re all healthy people, you know, middle-aged people. And then they just followed him for years and looked for the relationship between some something, they measured either a sum, they developed the term risk factor, the Framingham group, there’s nobody used that term before. And nobody knew it that nobody knew that smoking was related to a high risk for cancer or heart disease, they didn’t know high blood pressure was they didn’t know high cholesterol. So that’s how they discovered these risk factors. And so they’re like Framingham, there are cohorts like that all around the world. And so we have a collaboration with many of those cohorts, and the ones that have measured fatty acids in the blood and the ones we work together. And we found when we asked the question, of all these cohorts and several, several 1000 people together, is there a relationship between the blood Omega three-level and your risk for dying over time? And of course, you know, the window, the average window of time between blood drawing and when we stopped following up on people, it’s like 16 years, 1316 years, something like that. So it’s a, you know if you study Omega three levels and 10-year-olds, and ask, what’s the mortality in the next 10 years, you’re not going to find anything because nobody’s gonna die. You’ve got to study people toward the ...
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    1 h y 9 m
  • [EP.13] Why Extra Stem Cells Really Accomplishes A Slower Rate Of Aging

    [EP.13] Why Extra Stem Cells Really Accomplishes A Slower Rate Of Aging
    Dec 20 2023
    Dr. Joel Rosen:Alright, so our next guest is Christian Drapeau. He is a stem cell scientist, author, and creator of this first stem cell supplement. He holds a graduate degree in neurophysiology, and he’s been involved in medical research for 30-plus years, of which the last 20 years have specifically been dedicated to stem cell research. He’s the author of five books, including the best-selling Cracking the Stem Cell Code, he has published dozens of scientific papers on brain research and biological process processes, which we’ll be asking about endogenous stem cell mobilization. He’s lectured over 50 countries on stem cell research. He is known by scientists, physicians, and biohackers alike as the expert and pioneer in this field. Thank you so much for being here today. Christian, I could go on but I want to get the good stuff here today. Christian Drapeau:Thank you. Thank you. My pleasure. Yeah, so Dr. Joel Rosen:I you know, I like to prepare for these, these interviews, and I’ve done some research I know that in 94, you started with your blue-green algae research, but it wasn’t really until 2001 Were the article that you read turned blood into the brain. And like you said, as well, a lot of these times these amazing research articles come out, but they don’t register a glitch in the radar. Why was it that that article turning blood into the brain was so profoundly changing for you? Christian Drapeau:Well, to tell the truth, this article was sent to me soon after it was published, and it sat on my desk for probably three, or four months. So I read it the first time and it did not register. And I was cleaning my desk, and that paper was still there on my desk, and I read it again. And then that’s when slowly the thoughts started to trickle, and we need to look at it in the context of where we were at the time. So we had published not long before, that polysaccharides from that blue-green algae, were stimulating NK cell migration in tissues. So in the back of my mind was that data that there was something it is blue-green algae that mobilized immune cells taken in very broadly, my background is brain research, I know, we know, we were told that we cannot make new neurons. So finally reading that paper, and reading that stem cells from the bone marrow, could go to the brain and become a brain cell, which is a type of cell that we were told in neurology, you cannot regenerate your brain. I knew from just my basic class of med class that stem cells are only known to be precursors to blood cells. And suddenly, I’m thinking about when we were talking about the release of stem cells migrating into a tissue, and we showed that blue-green algae were supporting the migration of NK cells. So this sort of amorphous idea started to shape itself in my brain thinking that what if that plant could support the migration of stem cells in tissues? So it’s just reading it? And it started to be an answer a potential answer to a question that, that we had for several years, we did not have a way of explaining how this plant was leading to benefits touching so many aspects of human health. Right? Dr. Joel Rosen:Okay, so going forward from there, because I want to get your insight on this, and how research continues to propel us forward. But there’s been a lot of skepticism about the landscape and the controversy of stem cells. So given that, that article just sort of planted the seed for you, Christian, to tell us about where we come from, or what the initial, I guess, the landscape was, in terms of how stem cells and even more plant-based support for stem cells has been was initially received and where it is now? You know, Christian Drapeau:I liked these questions, because, to me, everything that we’re facing, and we’re looking at right now, in terms of what we have done with plants, but also the whole landscape of stem cell research, is an amazing example of the real life of scientific discoveries and scientific development, the interaction of scientific development, with business development, with policy development. All of this was so complex that if we knew today, so if we knew then what we know today, I guarantee you, we would not have today, the landscape that we have, things would have evolved differently. So and I’ll come back to that in a second. So when the first observations were made, we’re in early 2000 and 2001, that stem cells known for decades to be precursors to blood cells, were finally known to have the ability to become cells of many different tissues. At first, the observation or the belief was that, Okay, we’re ready to accept that they can be more than just blood cells, but we’re not ready to accept that they can become everything, yet. The data was there, right there. When I’m talking about the process of scientific discovery, we can observe and document the only things that we can accept, if there’s something that we cannot accept, we can observe it ...
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    1 h y 9 m
  • [EP.12]Powerful Genetic Testing: Learn the Effects of Genes On Your Longevity

    [EP.12]Powerful Genetic Testing: Learn the Effects of Genes On Your Longevity
    Dec 13 2023
    Dr. Joel Rosen:Right welcome back to another edition guys. And I’m excited to interview Alan Robinson. He is the founder of Genetic Insights and founder of Feel Younger. His goal is to empower committed and self-responsible people with the science-based tools they need to feel younger and improve their health. I first became interested in health and anti-aging because of his own experiences and the many health challenges throughout his own life, including chronic fatigue, chronic pain, malnutrition, hypothyroidism, IBS, and reoccurring infections, such as SIBO, Candida, and sinusitis, which made him feel way older than he was. And when conventional medicine practitioners weren’t able to help him set all of this out in desperation, he had to look within and figure it out on his own. So that’s what we’re going to be talking to him about today his health journey, how he improved his health and eventually resolved his issues, and lifelong interest in health, energy, and wellness, and the companies that he’s founded to help other people with the same problems. Oh, and thank you so much for being here today. Elwin Robinson:Thank you so much for having me, Joe. It’s a pleasure. Dr. Joel Rosen:Yeah. So you know, I’m excited to compare your journey and my journey, as it relates to what you do now with the genetic insights and how to feel younger. Perhaps you can just give us the Cliff Notes version of at worst what it was like for you when you were suffering from your health challenges. Elwin Robinson:Yeah, sure. So, you know, most recently, and that’s really what led to the founding of those two companies that you mentioned. So I’ll start at that point. I’ve been doing well for a long time after having health issues earlier, and I thought I’d been doing great. So long as I avoided certain foods, I was on top of the world, you know, plenty of energy. And I’d gone from, you know, kind of doing minimum wage jobs in my 20s to be able to start several businesses and travel the world and all that kind of cool stuff, right? I was enjoying life. And then suddenly, I got struck down with this pain condition where I kept having pain around my midsection, and no one was able to work out what it was. I had, you know, CT scan, MRI, blood tests, all of that kind of, you know, typical stuff, and then all kinds of other practitioners as well. Functional Medicine naturopath, acupuncturist chiropractor, osteopath, I mean, you know, the list goes on and on and on. All trying to work out what was going on. I had a few different theories, but no one was able to help. Along with that the constant pain and discomfort this, these digestive issues went along with it. And it got so bad that I wasn’t that I could list on one hand the food I can eat without having some kind of really unpleasant reaction. Even those foods I didn’t do very well on and I just started wasting away. I mean, I’m six foot three, and I think I got down to one 20 pounds, something like that, so I was really, I wouldn’t be emaciated might be a bit far. But for someone who’s trying to eat as much as possible, I was, you know, seriously wasting away. Along with that came extreme fatigue, extreme anxiety, you know, like being emotionally all over the place, as I said constant pain, and I wasn’t able to function. And I tried all the usual kinds of things, things I already knew to do to be healthy, because I already lived from the surface, maybe not to someone as sophisticated as yourself. But to any normal person, I would seem to live an extremely healthy lifestyle. And yet, you know, it wasn’t working I as I said, tried every practitioner under the sun, and none of them were able to help either. And eventually, I just, I realized that, you know, I was going to have to work this out for myself. The first breakthrough came through doing a kind of genetic testing. That was where I first got, maybe not all the answers, but the first clues as to what might be going on and helped me to work it out. Dr. Joel Rosen:Well, I’m glad that you did. And now you’re here to help other people. An interesting question is, I had contact with the patient the other day, and she’s dealing with, you know, right upper quadrant pain. And I was getting just sort of background information on what she’s been dealing with and what she’s done. And I asked her about the genetic test. And she looked at me like, that was the most craziest question, why would she want to look at genetics? What does that have to do with anything? So I guess the question would be, how did you go from learning all the things that you did with what didn’t work and having to take, the ball in your own hands and figure this out on your own? And how did that get into the world genetics is the next option. Elwin Robinson:It’s pretty random, to be honest, I mean, you know, I guess the kind of person who watches this kind of podcast is similar in that they become a ...
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    56 m
  • [EP.11]The Shocking Truth Why Cortisol Is The Rapid Aging Hormone

    [EP.11]The Shocking Truth Why Cortisol Is The Rapid Aging Hormone
    Dec 6 2023
    Dr. Joel Rosen:All right, I am super excited to be interviewing Georgi Dinkov a second time. For those of you who know who he is, he doesn’t need a bio. But for those that may not know who Georgie didn’t cough, is, there’s so much to say and so much to get to today. I’m going to abbreviate his bio, but basically, he is a self-taught guy. His interest in health topics continued after he left his job. While researching aspirin and its effects on the brain circa 2011 11, he stumbled on Ray Pete’s website, and I think that’s what dug down into the bioenergetics field. His ideas on Bennett bioenergetics which is controlled by dietary and environmental factors as the ultimate causal factor in health disease and even aging immediately appealed to Georgia. And since then, he’s been doing research in that field. So Georgia, I’m super excited to get started. Thank you so much for joining us. Georgi Dinkov:Thanks for inviting me again. Hopefully, it will be I’ll be useful to your listeners. Oh, yes. Dr. Joel Rosen:Listen, I went through that interview several times. And I came up with some great questions for you today. So for those who want to hear the past interview, we got into metabolic flexibility. We’ll leave links there. And Georgie, as I was telling you, before we got started, I walked away with a lot of aha cars that were contrary to what’s being taught. And I’ve gone down the cortisol rabbit hole, if you will. And even just our conversation when we just had that amazing insight has shifted my perspective. And I wanted to share that. So cortisol is not what we thought it was the truth behind it is it’s a rapidly aging stress hormone. One of the sacred cows or the contrarian thinking is that cortisol is anti-inflammatory when in fact, it’s pro-inflammatory. So maybe in your in your amazing way of bringing difficult concepts into an easy, understandable way. Explain that to the person who thought, well, cortisol is anti-inflammatory, and I take prednisone hydrocortisone, for an anti-inflammatory immune response or suppression, but ultimately, it’s putting more oil on the fire perhaps. So maybe let’s go into that. Georgi Dinkov:I think probably the best comparison that I can give you is with opioids, which are widely used for pain management in the medical field, and a lot of people are abusing them for these pain-relieving properties. It’s very well known that basically, if you continue using opioids, you develop tolerance to them, and then it and not only that, you’re going to start needing higher and higher doses to be able to tamp down the same level of pain. But eventually, if you try to wean off or you stop the opioids, there will be a baseline of pain, that’s going to shoot up tremendously. In other words, you’re going to be in a worse position than you started. And the pathways for the opioids are fairly well known. They increase reluctant histamine and serotonin, and they also increase the expression of an endotoxin receptor known as TLR four. All of these are known to be involved in chronic pain. So while you’re taking opioids back activation of the opioid receptor, which is a receptor that our endogenous opioids known as the better endorphins also activate, yes, you are kind of inhibiting the signals, at least the peripheral signals from for pain to reach the brain and that are kind of registered as a pain signal. But it’s while you’re doing that you’re up-regulating the machinery that causes these pain signals to travel much more rapidly. So as soon as you stop the opioid, you’re in a worse position than where you started. So you kind of like, you know, in a catch-22 or, or actually, once you, once you start, you can stop unless you’re taking care of, you know, kind of like, unless you also take care of reducing these inflammatory mediators that were upregulated while using the opioids. And most people are not doing that simply because for a lot of, you know, whenever you prescribe opioids for pain, there’s there’s little concern, and now it’s starting to become a concern. However there was little concern about the long-term effects on pain. Now, doctors are starting to find out through various long-term studies that people who are using opioids long-term, end up being worse, right? Their pain starts to become unmanageable. And once they become resistant to the opioids, there’s very little you can do for them. And maybe the opioids aren’t the kind of like the end stage of pain treatment. In the hospital, they’re usually given to terminal cancer patients, or just in general terminal people just to kind of like ease the transition to them dying. But it’s really like a last resort step. So if patients stop responding to opioids, then there’s very little that the doctor can do for them, or at least that’s that’s what they think. So there wasn’t much of a thought to this process. But now they’re starting to find out that...
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    1 h y 23 m
  • [EP.10]Mastering Your Biohacker’s Dashboard: How To Track Your Hacks Like a Pro

    [EP.10]Mastering Your Biohacker’s Dashboard: How To Track Your Hacks Like a Pro
    Nov 22 2023
    Dr. Joel Rosen:Welcome to the age-reversing blueprint podcast where we discuss tools and tips to help you reverse your age naturally. David Korsunsky:Let’s take a few of some of the more interesting ones that I’m working on right now. Okay, which would be hyperbaric oxygen, infrared sauna, cold plunge PEMF just down the street from my house, I can go in there and I pay 200 bucks a month. And they got everything I want unlimited. H BOD cold plunges. So I go in there, I do my 30 minutes in the sauna. I do five minutes in the cold water and I do a P E and F. I will see my aura HRV is close to double on those nights. Those technologies were not accessible to us the masses just a couple of years ago. There’s all these recovery lounges popping up. And here’s why I like these places. We’re in such a hyperstimulated world. We work ourselves like crazy. These are dedicated spaces. It’s like the spa. But with all these new health optimization technologies. So inside one of these recovery lounges, I’m going this afternoon it’s Friday. I’ve been busting ass all week. I blocked two hours on my calendar to go and do recovery work. I’m gonna go to two sessions Am I to two plunges of contrast therapy, but I’m creating space in my life. to specifically go and work on recovering my body Dr. Joel Rosen:right everyone, welcome back to another edition with my new guest Dave Korsunsky. He is the founder and CEO of Heads Up Health. He has a digital health analytics company based in Scottsdale Arizona, and avid health and Susie’s himself, David. He makes everyone’s life easier and helps them to control their health through effective data tracking. Before founding heads up, David worked at Cloud Physics as a data analyst company collecting and analyzing a bit of what the ADB David billion 80 billion 80 billion data points per day. He also spent seven years at V malware in director-level leadership roles where he built partnerships with the world’s largest software companies, including Oracle, IBM, SAP, epic Cerner, and more. David holds a Bachelor of Science degree in mathematics, a Master of Business Administration, and a Master of Science, and he is in the emerging field of neuroscience and based leadership. So David, thank you so much for being here. Thanks, David Korsunsky:brother. It’s good to reconnect with you. We just hung out a couple of weeks ago in Miami. And here we are again. Yeah, Dr. Joel Rosen:it’s weird to read the Bible and read it as David. I only know Dave. David Korsunsky:Well, you don’t even call me that. You call me the names of hockey players from the 70s to the 80s. That’s right. We have Dr. Joel Rosen:a little running joke on us Canadians, you know, the one with the obscure hockey players. So yeah, it was nice to reconnect and I did enjoy it wasn’t just blowing smoke up your skirt. I enjoyed your conversate you presented at the Biohacking Conference, which was entitled The Biohackers Dashboard, how to track your, your your hacks, I’ve asked you if we can expand that and not just the biohackers dashboard, how to track your hacks but how to track your five hacks. So why don’t we just kind of get into a brief overview of I know we had talked before how you got heads up health company to get into existence in the first place. David Korsunsky:Yeah, well, I was living in Silicon Valley at the time and working for a tech company out there and this was like, the early days of biohacking. So 2010 and 2011 None of this stuff was on anyone’s radar screen except for a very obscure group of people doing at that time what was called Quantified Self. Now we call it biohacking. But it was the same thing. I got into that community and realized that it was incredibly powerful. However, there were no accessible ways for people to figure out if their health was improving or not. So like there were all these cool things. You could try different diets, different exercise regimens, different supplements, different things to try to move the needle. But how do you know if it worked or not? And some of this stuff, you’re spending a lot of money on it. You’re spending a lot of money on nutrition and the gym, and supplementation and all these things to try to be, quote unquote healthier. So I saw that, despite all the amazing technology coming on the market, and all of the amazing new ways that we had available to us to improve our health, like, I don’t know, infrared sauna, for example, I needed to, to measure what was working, because what works for me is not necessarily going to work for you. And so, one therapy that works for a certain individual doesn’t work for the next. So the only way to know for yourself is to test if it works. So that was kind of the origin story for heads up. I’m like, Hey, there’s all this cool stuff out there. There’s all this data, and it sucks. There’s no way to just I just want to see all my numbers on one screen. These are the 10 ...
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    1 h y 17 m