• Diazepam

  • Dec 23 2022
  • Length: 2 mins
  • Podcast

  • Summary

    • Trade: Valium 
    • Class: Benzodiazepine
    • MOA: Binds to the benzodiazepine receptor and enhances the effects of GABA
    • Indications: Anxiety, Skeletal muscle relaxation, anticonvulsant 
    • Contraindications: Children younger then 6 months, acute angle glaucoma, CNS depression, alcohol intoxication. 
    • Side effects:  Respiratory depression, drowsiness, fatigue, headache, pain at the injection site, confusion, nausea, hypotension, cardiac arrest at high doses
    • •Dosing:

    Adult: 

    Anxiety: 2-10mg IV/IM

    Seizure: 5-10mg IV/IO

    Pediatric:

    Anxiety: 0.2 – 0.3mg/kg IV/IM

    Seizure:  Older then 5 years: 1mg IV/IO

    Older then 30 days less then 5 years: 0.2 to 0.5mg IV/IO

                    Neonate: 0.1-0.3mg/kg IV/IO


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