Lyme disease, a tick-borne illness caused by Borrelia burgdorferi, is a growing public health concern, especially in areas with high tick populations. While antibiotics can often treat the infection if caught early, many patients suffer from chronic symptoms long after the bacteria are gone. This condition, known as chronic Lyme disease or post-treatment Lyme disease syndrome (PTLDS), can be life-altering — leading to fatigue, joint pain, cognitive issues, and more. In recent years, regenerative medicine has emerged as a promising frontier in treating difficult, chronic illnesses like Lyme disease. At the forefront of this innovation is Dr. David Greene Arizona, a former orthopedic surgeon and the founder of R3 Stem Cell, a global leader in regenerative therapy. Dr. Greene is now helping shine a light on the potential of stem cell therapy as a supportive option for managing chronic Lyme disease symptoms.What Are Stem Cells and How Do They Work? Stem cells are the body’s raw materials — cells from which all other cells with specialized functions are generated. In therapy, mesenchymal stem cells (MSCs) are often used due to their ability to reduce inflammation, modulate immune responses, and support tissue repair. For Lyme disease patients, these properties could be incredibly valuable. Many of the lingering symptoms of Lyme are thought to result from ongoing immune system dysregulation and inflammation — not necessarily active infection. This is where stem cell therapy may play a role.Dr. David Greene’s Perspective According to Dr. Greene, stem cell therapy doesn’t target the Lyme bacteria directly. Instead, it helps rebalance the immune system, reduce chronic inflammation, and stimulate the body’s own repair mechanisms. “Lyme disease affects people in such different ways that it can be incredibly difficult to treat effectively,” says Dr. Greene. “Stem cell therapy offers a way to support the body’s healing response, especially in patients who have tried everything else and are still suffering.” Through his clinics and educational outreach, Dr. Greene emphasizes that stem cell therapy should be considered a complementary approach, ideally integrated with other medical strategies under a healthcare provider’s guidance.What the Research Says While clinical research into stem cell therapy specifically for Lyme disease is still emerging, studies have shown the immunomodulatory and anti-inflammatory effects of stem cells in other chronic illnesses, such as autoimmune diseases and neurological conditions. Some Lyme disease patients who’ve undergone stem cell treatment report improvements in fatigue, brain fog, pain levels, and overall function. However, outcomes can vary, and Dr. Greene is clear that stem cell therapy is not a guaranteed cure — but rather a tool that might improve quality of life for select individuals.
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