• Harnessing Proteoforms to Understand Life's Complexity

  • Jun 19 2024
  • Length: 25 mins
  • Podcast

Harnessing Proteoforms to Understand Life's Complexity  By  cover art

Harnessing Proteoforms to Understand Life's Complexity

  • Summary

  • Proteins are far more than just the output of genes. They can be modified in myriad ways to produce millions of proteoforms with altered dynamics, localization, and function. For a comprehensive understanding of biology that will propel drug development and biomarker discovery forward, we need to be able to measure proteoforms routinely. In this episode, Parag and Andreas discuss the incredible value that will come from studying proteoforms and describe what it will take to make proteoform measurement a routine part of biology research.

    Chapters:

    00:00 - Introduction to proteoforms

    09:38 - Evidence that proteoforms are important and how we can use proteoform data

    19:28 - Technology advances needed to understand proteoform biology

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