• Hydroxocobalamin

  • Dec 8 2022
  • Length: 1 min
  • Podcast

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Hydroxocobalamin

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  • Summary

    • Trade – Cyanokit
    • MOA:  Antidote, cyanide poisoning adjunct Binds with cyanide to form nontoxic cyanocobalamin, preventing its toxic effects; excreted renally
    • Indications: Treatment of known or suspected cyanide poisioning.
    • Contraindications:  None is the emergency setting
    • Side Effects:  Hypertension, allergic reactions, GI bleeding, nausea, vomiting, dyspepsia, dyspnea, dizziness, headache, injection site reactions.
    • Dosage:  

    Adult: 5 g IV infusion over 15 minutes at a rate of 15 mL/min.

    Pedi:  70 mg/kg IV one time, may be repeated one time at the same dose.
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