David and Rob are always on TV! “SEAL Team” and “Bones” actor David Boreanaz joins Rob Lowe to discuss the final season of “SEAL Team” on CBS, nearly drowning in alligator-infested waters, their memories of working with Rob’s brother Chad, getting discovered while walking his dog, and much more.

Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!

Lamorne and Rob had so much fun on the set of “Unstable” season 2 (out now on Netflix!). “New Girl” star Lamorne Morris joins Rob Lowe to discuss his role as Peter in “Unstable,” the legacy of Chris Farley, how he prepared for the his film about the first episode of “Saturday Night Live,” his Emmy-nominated work in the new season of "Fargo,” some of the advice Rob gave to Lamorne on-set, and much more.

Catch Rob and Lamorne in season 2 of "Unstable," on Netflix now!

Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!

Jamie and Rob want you to listen to your dreams! IT Cosmetics founder and podcast host Jamie Kern Lima joins Rob Lowe to discuss her journey from Denny's waitress to the founder of a billion-dollar cosmetics brand, finding inspiration in dreams, cheering yourself on, not taking rejection personally, and her new podcast, “The Jamie Kern Lima Show.”

Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!

Rob and Casey love talking movies! Casey Affleck joins Rob Lowe to discuss his new film, “The Instigators,” the value of sobriety, the understated genius of Matt Damon, their first movie theater memories, the “Outsiders” audition process, actors as directors (and directors as actors), some excellent advice from Michael Caine, and much more.

Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!

Season 2 of “Unstable” is now streaming on Netflix! John Owen Lowe and “Unstable” Season 2 showrunner Andrew Gurland join Rob Lowe to discuss the new season of their Netflix show, the increasingly blurry line between Rob and John Owen’s characters and themselves, catching up on “Real Housewives of New Jersey,” the amazing unpredictability of Fred Armisen, the character they wish was serving as host for this episode, and much more.

Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!

Fred and Rob are so happy to be working together again on their Netflix show “Unstable!” Fred Armisen joins Rob Lowe to discuss the new season of “Unstable” (out August 1st), Fred’s approach to playing Uncle Fester in “Wednesday,” shooting “The Floor” in Ireland, dinner for Mick Jagger, Rob’s field trip to the CERN particle accelerator, starring in the official music video for George Harrison’s “My Sweet Lord,” and much more.

Inspired by Walmart, Rob is opening up the Lowe Down Line this summer to answer your questions about cultural trends, fandoms, home design, and all things style! If you’ve got a question, just leave me a message at (323) 570-4551 and tune in to the next installment of the Lowe Down Line.

Rob Lowe welcomes back one of his favorite podcasters and now radio host, Andy Richter! In this episode they get into Andy’s new call-in show on SiriusXM, Howard Stern, how game shows are one of the last universal forms of entertainment, British comedy, and more.

Inspired by Walmart, Rob is opening up the Lowe Down Line this summer to answer your questions about cultural trends, fandoms, home design, and all things style! If you’ve got a question, just leave me a message at (323) 570-4551 and tune in to the next installment of the Lowe Down Line.

Dan and Rob think history is exciting! "Hardcore History" host Dan Carlin joins Rob Lowe to discuss watching history unfold in real-time, why Rob believes 1976 to 1986 was the best time to be alive, whether the United States is an empire in decline, why the presidency of JFK might be even more important than we initially thought, the evolution of television journalism, and much more.

Inspired by Walmart, Rob is opening up the Lowe Down Line this summer to answer your questions about cultural trends, fandoms, home design, and all things style! If you’ve got a question, just leave me a message at (323) 570-4551 and tune in to the next installment of the Lowe Down Line.