Dr. Jess Wade is a physicist at Imperial College London who’s made it her mission to write and update the Wikipedia pages of as many women in STEM as she possibly can. She inspired us at Lost Women of Science to start our own Wikipedia project to ensure that all the female scientists we profile have accurate and complete Wikipedia pages. In this episode, Jess talks with us about what she does and why she does it.

Dr. Nancy Hopkins, a molecular biologist who made major discoveries in cancer genetics, became an unlikely activist in her early fifties. She had always believed that if you did great science, you would get the recognition you deserved. But after years of humiliations — being snubbed for promotions and realizing the women's labs were smaller than those of their male counterparts — she finally woke up to the fact that her beloved MIT did not value women scientists. So measuring tape in hand, she collected the data to prove her point. In The Exceptions: Nancy Hopkins, MIT, and the Fight for Women in Science, Kate Zernike tells Nancy's story, which led to MIT’s historic admission of discrimination against its female scientists in 1999. Host Julianna LeMieux talks with Kate and Nancy about the journey.

“The only time I ever saw something that I thought was abnormal…there was a human arm in the refrigerator,” said J. Peter Willard about his aunt, Mary Louisa Willard. Otherwise, he insisted, she was just “very normal.” But Mary Louisa Willard, a chemistry professor at Pennsylvania State University in the late 1920s, left a strong impression on most people, to say the least. Her hometown of State College, Pennsylvania, knew her for stopping traffic in her pink Cadillac to chat with friends and for throwing birthday bashes for her beloved cocker spaniels. Police around the world knew her for her side hustle: using chemistry to help solve crimes.

When Laura J. Martin decided to write a history of ecological restoration, she didn’t think she would have to go back further than the 1980s to uncover its beginnings. What she found, however, deep in the archives, was evidence of a network of early female botanists from the turn of the last century who had been written out of history. Wild by Design: The Rise of Ecological Restoration sets the record straight. It tells the stories of Eloise Butler, Edith Roberts and the wild and wonderful gardens they planted and studied.

In our final episode, we explore Dorothy Andersen’s legacy — what she left behind and how her work has lived on since her death. Describing her mentor’s influence on her life and career, Dr. Celia Ores gives us a rare look at what Dr. Andersen was really like. We then turn to researchers, physicians, and patients, who fill us in on the many areas of progress that have grown out of Dr. Andersen’s work. These major developments include the discovery of the cystic fibrosis gene, the tremendous impact of the drug Trikafta, and the lifesaving potential of gene editing techniques. We end the episode with an update on the effect Trikafta has had on the lives of many CF patients, who can now expect to live a normal life.

The missing portrait of Dr. Andersen takes us on a journey into the perils of memorialization and who gets to be remembered. Dr. John Scott Baird, Dorothy Andersen’s biographer, looks for the portrait, and Drs. Nientara Anderson and Lizzy Fitzsousa, former medical students at Yale University, explain how “dude walls” — the paintings of male scientists that line institutional walls — can have an insidious effect on those who walk past them every day. And we go back to Columbia University to give you an update on the hunt for the missing portrait.

Our associate producer, Sophie McNulty, rummages through boxes in a Connecticut basement, looking for clues to Dorothy Andersen’s life story. Pediatric critical care physician Dr. John Scott Baird, who published a biography of Dorothy Andersen in 2021, suggests we take a second look at the conventional wisdom surrounding the evolution of cystic fibrosis research in the 1950s. And in this updated episode, we interview science historian Margaret Rossiter, who coined the term “Matilda Effect” to describe how credit for work done by female scientists too often goes to their male colleagues. We examine how this affected Dorothy Andersen and her groundbreaking research into cystic fibrosis.

A few important things have happened in the three years since we first aired The Pathologist in the Basement, the story of Dr. Dorothy Andersen, the first to identify cystic fibrosis. It’s safe to say that Dr. Anderson is now a little less lost. In Episode 1, Dr. Andersen sleuths her way to the discovery of cystic fibrosis, a fatal disease that affects the lungs, the pancreas, and a host of other organs. So, who was Dorothy Andersen, and how did she come to make this seminal medical contribution?