It is the time of big promise in the diagnosis and treatment of Alzheimer’s Disease (AD). There are dozens of genetic risks discovered in recent years. There are also emerging blood tests whose performance in diverse groups of patients is currently being confirmed. New disease-modifying drugs help to remove beta-amyloid plaques from the brain. While AD is a complex disease and its onset is connected to multiple biochemical pathways in cells, the new treatments target a core component of Alzheimer’s Disease.

In this episode of NeuroCentury, its host Paweł Świeboda talks to Professor Stephen Salloway, one of the leading scholars working on biomarkers and drug development for prevention and early treatment of Alzheimer’s Disease. He is Professor of Psychiatry and Human Behaviour and Professor of Neurology at Brown University. He is also Founding Director of the Memory and Ageing Program at Butler Hospital.

The conversation helps to disentangle what the new era in diagnosis and treatment of AD can bring, with the advent of monoclonal antibodies and the emergence of new generation brain health services. Rethinking the care journey is part of the process, since treatments need to start before symptoms emerge, or possibly even before the amyloid build-up. Future discovery research will go beyond lowering of amyloid levels to have an even bigger impact on the disease.

#neurocentury #AD #Alzheimer’sDisease #brain #brainhealth

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neurocentury.com

Music for the NeuroCentury podcast is composed by Rafał Kulczycki

Ascent of AI in healthcare opens the way to precision and personalized medicine becoming a standard of care in neurology. One important aspect is extracting more meaningful data from brain imaging and scans, given how crucial they are for the diagnosis and monitoring in neurology. Facing rising demand for brain MRI procedures, radiologists can increasingly have their AI companions, helping them to manage the task, as clinical burdens and disease complexity continue to increase.

In the episode of NeuroCentury, its host Paweł Świeboda discusses these game-changing developments with Wim Van Hecke, founder and CEO of Icometrix, a company that is enabling radiologists and physicians optimize their workflows and clinical decision-making Wim trained as engineer and specialized in biomedical engineering and neuroimaging. He is author or co-author of over 200 scientific publications and editor of a clinical neuroimaging handbook. He is also a visiting professor at Free University of Brussels.

Icometrix has developed a suite of tools for quantitative assessment of brain MRI scans in the different fields of neurology. It is now transforming the care of patients with neurological disorders. As disease-modifying treatments start to become available for Alzheimer’s disease, the importance of advanced diagnostic and prognostic technologies and biomarkers coming together to standardize care pathways, has never been greater.

#neurocentury #healthcare #brain #neurotechnology #neuroimaging #AI

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neurocentury.com

Music for the NeuroCentury podcast is composed by Rafał Kulczycki

What are the trends on the market for medical technologies and medical devices in the neuro space? How much of the impressive innovation coming out of the labs carries the promise of making impact on the lives of patients? In this episode of NeuroCentury, Paweł Świeboda talks to Enric Claverol-Tinturé, Programme Manager for Medical Technologies and Medical Devices at the European Innovation Council, the EU’s prime vehicle for funding breakthrough innovation.

Enric is well versed in all matters neuro. He has a PhD degree in engineering and neuroscience and worked as scientist at the California Institute of Technology and the Barcelona-based Bioengineering Research Centre. He then run a spin-off company and founded a technology start-up. Enric’s ample experience in funding innovation includes his tenure as Director General of the Catalonia Foundation for R&I and the current pivotal role at the EIC.

Paweł and Enric discuss promising developments in neuro-electronics and neurotechnology more broadly. They reflect on how interdisciplinary collaboration can be further encouraged, so as to leverage advances in compact electronics, powerful computation and brain medicine. Enric explains what type of projects the EIC looks for and what entrepreneurial researchers as well as current and future founders should consider when preparing to apply for an EIC grant.

#neurocentury #neurotechnology #neuroscience

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neurocentury.com

Music for the NeuroCentury podcast is composed by Rafał Kulczycki