This episode features Paradromics CEO Matt Angle in a compelling discussion with Amit Etkin, Founder and CEO of Alto Neuroscience; Maryam Shanechi, Dean's Professor in Electrical and Computer Engineering, Neuroscience, Computer Science, and Biomedical Engineering at USC; and Prasad Shirvalkar, Associate Professor of Neurological Surgery, Neurology and Anesthesia at UC San Francisco. They delve into the intersection of neurotechnology and psychiatry, discussing innovative approaches to treating mental health disorders, the potential of machine learning models, and the challenges associated with obtaining and analyzing brain data. The discussion emphasizes the importance of interdisciplinary collaboration and the promising future of personalized therapies for psychiatric conditions. They also address the limitations of current diagnostic tools like the DSM and the need for scalable, real-world solutions.

Guest Quote:

“There's artificial intelligence and there's actual intelligence. And that actual intelligence, when it comes to analyzing data, I feel goes a really, really long way. True subject matter expertise.” - Amit Etkin

Timestamps:

*(00:00) Welcome to Neurotech Pub

*(00:45) Icebreaker: Unpopular Beliefs

*(05:36) Non-surgical brain activity recording and diagnostics

*(13:32) Understanding pain: Subjective reports vs. physical representations

*(16:33) Rethinking psychiatry and DSM alignment

*(21:07) Determining brain data needs and tool validation

*(26:47) The need for explainability in AI algorithms

*(35:49) Timescales in mental health interventions

*(41:22) Advice for aspiring neurotech researchers

*(46:25) Closing Thoughts

Want More?

Learn about Neurotech Pub on Twitter

Follow Paradromics on Twitter, LinkedIn, and Instagram

Follow Matt on LinkedIn and Twitter

This episode features Paradromics CEO Matt Angle in a compelling discussion with Sumner Norman, Co-founder & CEO at Forest Neurotech; Ryan Field,CEO at Kernel; and Mary Lou Jepsen, Founder and CEO of Openwater. They share their career influences, discuss the challenges of managing interdisciplinary teams, and explore the future of neuroimaging and brain-computer interfaces (BCIs). Delving into ultrasound and optical-based techniques, they highlight the transformative potential of non-invasive methods for diagnosing and treating brain conditions. Furthermore, they addresses regulatory hurdles, the evolution of focused research organizations, and offers valuable advice for early-career researchers on leveraging industry trends and fundamental research to drive technological advancements.

Guest Quote:

“And I think what we're trying to work on is the silicon hospital of the future with this capability, like the modern smartphone, that can reach everybody, regardless of income levels or borders.” - Mary Lou Jepsen

Timestamps:

*(00:00) Welcome to Neurotech Pub

*(00:06) Meet the Guests

*(02:48) Balancing Mentorship and Startup Demands

*(05:36) Interdisciplinary Challenges in Neurotech

*(07:11) Hardware Development and Efficiency

*(18:12) Medical Device Development and Regulatory Challenges

*(23:37) Technical Deep Dive: Optical and Acoustic Signatures

*(24:00) Ultrasound in Brain-Computer Interfaces

*(34:57) Near-Infrared Spectroscopy and Mental Health

*(55:55) Understanding Stroke and Thrombectomy

*(56:51) Innovations in Cancer Treatment and Blood Flow Analysis

*(57:39) Challenges and Trials in Medical Technology

*(58:42) Open Source Medical Technology and Global Collaboration

*(58:59) The Evolution of Brain-Computer Interfaces

*(01:02:42) Advancements in Ultrasound Technology

*(01:03:39) The Role of MEMS and Silicon in Medical Devices

*(01:09:29) The Importance of Fundamental Research

*(01:14:48) The Future of Neurotechnology and Industry Trends

*(01:17:58) Advice for Aspiring Researchers and Entrepreneurs

*(01:29:41) Leadership and Transition in Tech Companies

*(01:40:07) Focused Research Organizations and Their Impact

*(01:46:08) Final Thoughts and Optimism for Neurotech

Want More?

Learn about Neurotech Pub on Twitter

Follow Paradromics on Twitter, LinkedIn, and Instagram

Follow Matt on LinkedIn and Twitter

This episode features Paradromics CEO Matt Angle in a compelling discussion with Grayson Zulauf, CEO of Resonant Link; Alex Yeh, CTO and VP of R&D at Neuspera Medical; and Jacob Robinson, Founder and CEO of Motif Neurotech. They explore the latest advancements in neurotechnology, focusing on wireless power transfer, implantable devices, and brain-computer interfaces (BCIs). The conversation highlights transformative innovations in treating mental health conditions like major depressive disorder, OCD, and ADHD with less invasive wireless devices, enhancing patient care and acceptance. Personal stories and insights on market expansion and patient-friendly treatments are shared, along with valuable advice for investors on the potential of neurotechnology in improving overall mental health and medical care.

Guest Quote:

“The message that I would want to send is, there is a future in which we look at neurotechnologies no differently than we look at cardiac pacemakers.

These are life saving devices, in many cases less invasive than a device that goes in your heart. There's no reason why anybody wouldn't want to feel better. To be healthier mentally and just live a better quality of life. So that's what we're trying to enable” - Jacob Robinson

Show Notes:

*(00:00) Welcome to Neurotech Pub

*(00:46) Meet the Guests

*(02:45) Discussing Industry Competitors

*(09:54) Wireless Power Transfer in Medical Devices

*(16:38) Exploring Inductive and Magnetoelectric Power

*(27:35) Ultrasound in real-world devices

*(33:31) Patient Experience and Device Miniaturization

*(36:24) Designing for Patient Comfort and Practicality

*(38:20) Innovations in Power and Data Transmission

*(39:32) Miniaturization and Its Impact

*(41:12) Battery Technology in Medical Devices

*(43:19) Future of Implantable Batteries

*(45:16) Implanted Battery Companies Integer and Resonetics

*(46:31) Intermittent Stimulation and Therapy

*(49:28) Power Consumption in Future Implants

*(59:52) Data Transmission and Compression

*(01:05:42) Reflections on the Journey of Medical Innovation

*(01:08:36) Final Thoughts and Messages to Investors

Want More?

Follow Neurotech Pub on Twitter

Follow Paradromics on Twitter, LinkedIn, and Instagram

Follow Matt on LinkedIn and Twitter