Featuring an interview with Dr Matthew R Smith, including the following topics:

• Selection and sequencing of androgen-targeting therapies (0:00)
• Evidence-based selection of treatment for metastatic hormone-sensitive prostate cancer (25:07)
• New considerations with the use of PARP inhibitors for metastatic castration-resistant prostate cancer (mCRPC) (27:44)
• Role of novel radiopharmaceuticals for mCRPC (37:09)
• Promising investigational approaches for prostate cancer (42:38)

CME information and select publications

Featuring an interview with Dr Kimberly H Allison, including the following topics:

• Contemporary practices in pathology and reporting biomarkers of interest (0:00)
• HER2 testing across numerous solid tumor types (2:47)
• ER-low reporting category and pathologic interpretation (6:28)
• PD-1/PD-L1 testing methodology and challenges with bone biopsies (10:53)

CME information and select publications

Featuring a slide presentation and related discussion from Dr Kimberly H Allison, including the following topics:

• Pathological assessment of HER2 and appropriate testing methodologies (0:00)
• Effect of the DESTINY-Breast04 study on clinical practice (12:32)
• Relevancy of HER2-ultralow expression and implications of the DESTINY-Breast06 study (22:53)
• Future directions in the pathological and clinical assessment of HER2-positive breast cancer (31:06)

CME information and select publications

Featuring perspectives from Dr Dana M Chase, including the following topics:

• Introduction: ASCO 2024 Review (0:00)
• Ovarian Cancer (14:29)
• HER2 as a Therapeutic Target (29:18)
• Endometrial Cancer (38:55)
• Cervical Cancer (51:11)

CME information and select publications

Featuring an interview with Dr Jonathan W Goldman, including the following topics:

• Contemporary and Future Care for Patients with Nonmetastatic Non-Small Cell Lung Cancer (NSCLC) with an EGFR Mutation (0:00)
• Evolving First-Line Treatment for Metastatic NSCLC with an EGFR Mutation (21:05)
• Other Emerging Strategies for Relapsed Metastatic Lung Cancer (29:16)
• Emerging Role of Antibody-Drug Conjugates in the Management of NSCLC with an EGFR Mutation (37:59)
• Current and Future Management of NSCLC with an EGFR Exon 20 Insertion Mutation (45:29)

CME information and select publications

Featuring perspectives from Dr Nikhil I Khushalani and Dr Jason J Luke, including the following topics:

• Introduction (0:00)
• Evidence-Based Treatment of Nonmetastatic and Metastatic Melanoma — Dr Luke (2:49)
• Optimizing the Management of Nonmelanoma Skin Cancers — Dr Khushalani (36:54)

CME information and select publications

Featuring perspectives from Dr Rana R McKay and Prof Thomas Powles, including the following topics:

• Introduction (0:00)
• Management of Metastatic Clear Cell Renal Cell Carcinoma (RCC) — Prof Powles (12:39)
• Treatment Approaches for Nonmetastatic RCC; Optimal Care of Patients with Non-Clear Cell RCC — Dr McKay (49:27)

CME information and select publications

Featuring perspectives from Dr Scott Kopetz and Dr John Strickler, including the following topics:

• Introduction (0:00)
• Recent Therapeutic Advances in Colorectal Cancer (CRC) — Dr Strickler (1:53)
• New Developments in Targeted Therapy for Metastatic CRC — Dr Kopetz (35:11)

CME information and select publications