In the final part, Prendick finally escapes from the island and returns to humanity, only to be wracked by the idea that there is not really much difference between us and the Beast-Folk...

Montgomery cracks under the impact of Moreau’s death, leaving Prendick to face the Beast-Men of the island.

When the puma breaks free from Moreau's vivisection chamber, it results in a catastrophe that threatens the fragile order of the island.

Summoning the Beast Folk for tasting blood, a transgression of the Law, Moreau sets in motion a hunt that leads Prendick to consider the differences and similarities between these creations and humanity.

Having convinced Prendick that he poses no threat, Moreau explains his dedication to the theory and practice of vivisection, founded on his belief that pain is evolutionary waste to be ignored in his ceaseless attempt to create humans from animals. Prendick realises that the island is populated by the results of Moreau's previous attempts.

Horrified at the prospect of falling under Moreau's vivisection knife, Prendick flees further into the island. There he discovers extraordinary Beast-Men and is inducted into a mysterious form of religion before he is nearly hunted and killed.

Determined to escape the cries of the puma, Prendick is driven to explore the island. Encountering a strange figure, he is then stalked by a bestial creature. Barely escaping with his life, he makes a discovery that seems to confirm his worst fears…

As Prendick learns more about Moreau, the mystery of the island only deepens.