Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Results after Four Years of Screening for Prostate Cancer with PSA and MRI

Ziresovir in Hospitalized Infants with Respiratory Syncytial Virus Infection

Gene Therapy with Fidanacogene Elaparvovec in Adults with Hemophilia B

Journal of American Medical Association

Fever Prevention in Patients With Acute Vascular Brain Injury: The INTREPID Randomized Clinical Trial

Thrombectomy for Stroke With Large Infarct on Noncontrast CT

The TESLA Randomized Clinical Trial

Annals of Internal Medicine

Severe Maternal and Neonatal Morbidity Among Gestational Carriers: A Cohort Study

British Medical Journal

Model of integrated mental health video consultations for people with depression or anxiety in primary care

Lancet

Mineralocorticoid receptor antagonists in heart failure: an individual patient level meta-analysis

journal of Hepatology

B-cell characteristics define HCV reinfection outcome

Gastroenterology

Gut Microbiota-Derived Butyrate Induces Epigenetic and Metabolic Reprogramming in Myeloid-Derived Suppressor Cells to Alleviate Primary Biliary Cholangitis

Clinical Gastroenterology

Efficacy and Safety of Vedolizumab and Tumor Necrosis Factor Inhibitors in the Treatment of Steroid-refractory Microscopic Colitis: A Systematic Review and Meta-analysis

Clinical Infectious Diseases

Drivers of Geographic Patterns in Outpatient Antibiotic Prescribing in the United States

Nosocomial Infections in Adults Receiving Extracorporeal Membrane Oxygenation: A Review for Infectious Diseases Clinicians

sparent reporting of practices at individual facilities in future clinical trials.

Arthritis and Rheumatology

Prevalence and Risk of Immunostimulatory Herbal Supplement Treatment Among Autoimmune Dermatology Patients

Cardiology

Mineralocorticoid Receptor Antagonism Prevents Aortic Plaque Progression and Reduces Left Ventricular Mass and Fibrosis in Patients With Type 2 Diabetes and Chronic Kidney Disease: The MAGMA Trial

Journals of the American College of Cardiology

Antithrombotic Strategies in Atrial Fibrillation After ACS and/or PCI: A 4-Way Comparison From AUGUSTUS

JAMA Cardiology

Plasma Proteomics of Exercise Blood Pressure and Incident Hypertension

Journal of Clinical Endocrinology & Metabolism

The Spectrum of Dysregulated Aldosterone Production: An International Human Physiology Study

] Diabetes care

Effectiveness of Multilevel and Multidomain Interventions to Improve Glycemic Control in U.S. Racial and Ethnic Minority Populations: A Systematic Review and Meta-analysis

Neurology

Graded Multidimensional Clinical and Radiologic Variation in Patients With Alzheimer Disease and Posterior Cortical Atrophy

Chest

Changes in Spirometry Interpretative Strategies

The American Journal of Respiratory and Critical Care Medicine

Physiologic Effects of Extracorporeal Membrane Oxygenation in Patients with Severe Acute Respiratory Distress Syndrome

Clinical Journal of American Society of Nephrology

A Six-Year Follow-Up of Bloodstream Infections in Hemodialysis Facilities in the United States, National Healthcare Safety Network, 2020

Kidney International reports

Global aHUS Registry Analysis of Patients Switching to Ravulizumab From Eculizumab

Hi, This Week in Medicine, we will be discussing

First we will be discussing articles in New England Journal of Medicine

Long-Term Oxygen Therapy for 24 or 15 Hours per Day in Severe Hypoxemia

Community-Based Cluster-Randomized Trial to Reduce Opioid Overdose Deaths

Axatilimab in Recurrent or Refractory Chronic Graft-versus-Host Disease

Pomalidomide for Epistaxis in Hereditary Hemorrhagic Telangiectasia

Journal of American Medical Association

Risk Stratification in Nonischemic Dilated Cardiomyopathy Using CMR Imaging

Malaria Rapid Tests, Febrile Illness Management, and Child Mortality Across Sub-Saharan African Countries

Annals of Internal Medicine

Factors Associated With Recurrent Pediatric Firearm Injury: A 10-Year Retrospective Cohort Analysis

Class I Recalls of Cardiovascular Devices Between 2013 and 2022: A Cross-Sectional Analysis

British Medical Journal

Cumulative live birth rate of a blastocyst versus cleavage stage embryo transfer policy during in vitro fertilisation in women with a good prognosis

Lancet

Temporary mechanical circulatory support in infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials with 6-month follow-up

Gastroenterology

Resolution of Acinar Dedifferentiation Regulates Tissue Remodeling in

Clinical Gastroenterology

Symptom Outcomes of Celiac Disease in Those on a Gluten-free Diet

Clinical Infectious Diseases

Changes in the Appropriateness of US Outpatient Antibiotic Prescribing After the COVID-19 Outbreak

The Value of Outpatient Parenteral Antimicrobial Therapy: Better Care in 27 Minutes

Arthritis and Rheumatology

Returning Incidental Research Findings from FDG PET/CT to Participants

Circulation

Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy

Journals of the American College of Cardiology

Triglyceride Levels, Alirocumab Treatment, and Cardiovascular Outcomes After an Acute Coronary Syndrome

JAMA Cardiology

Postpartum Ambulatory Blood Pressure Patterns Following New-Onset Hypertensive Disorders of Pregnancy

Journal of Clinical Endocrinology & Metabolism

An Open-label Phase 2 Study of Eneboparatide, a Novel PTH Receptor 1 Agonist, in Hypoparathyroidism

Diabetes care

Association Between Accelerometer-Measured Irregular Sleep Duration and Type 2 Diabetes Risk: A Prospective Cohort Study in the UK Biobank

Neurology

Pathologic Substrates of Structural Brain Network Resilience and Topology in Parkinson Disease Decedents

Chest

Effect of Corticosteroids on Long-Term Humoral and Memory T-Cell Responses in Follow-Up Visit of Hospitalized Patients With COVID-19

The American Journal of Respiratory and Critical Care Medicine

Potential Diaphragm Muscle Weakness-related Dyspnea Persists 2 Years after COVID-19 and Could Be Improved by Inspiratory Muscle Training: Results of an Observational and an Interventional Clinical Trial

Clinical Journal of American Society of Nephrology

Lower-Dosage Acute Peritoneal Dialysis versus Acute Intermittent Hemodialysis in Acute Kidney Injury: A Randomized Controlled Trial

Kidney International reports

Phase 1b/2a Study Assessing the Safety and Efficacy of Felzartamab in Anti-Phospholipase A2 Receptor Autoantibody–Positive Primary Membranous Nephropathy

Hi, This Week in Medicine, we will be discussing

New England Journal of Medicine

Asciminib in Newly Diagnosed Chronic Myeloid Leukemia

Plozasiran, an RNA Interference Agent Targeting APOC3, for Mixed Hyperlipidemia

Zodasiran, an RNAi Therapeutic Targeting ANGPTL3, for Mixed Hyperlipidemia

Journal of American Medical Association

Telehealth vs In-Person Early Palliative Care for Patients With Advanced Lung Cancer: A Multisite Randomized Clinical Trial

Tenecteplase vs Alteplase for Patients With Acute Ischemic Stroke

Annals of Internal Medicine

Hospital Type and Resilience During COVID-19 Surges

British Medical Journal

Randomised controlled trials on radiation dose fractionation in breast cancer

Lancet

De-escalation to ticagrelor monotherapy versus 12 months of dual antiplatelet therapy in patients with and without acute coronary syndromes

Cancer Journal for Clinicians

Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States, 2019

Next we will be discussing articles In the field of Gastroenterology

Here are the articles from Clinical Gastroenterology

Endoscopic Glue Injection Versus Endoscopic Human Thrombin Injection for Bleeding Gastric

Clinical Infectious Diseases

Association Between Social Vulnerability and Streptococcus pneumoniae Antimicrobial Resistance in US Adults

Quantifying the Time to Administer Outpatient Parenteral Antimicrobial Therapy

Next we will be discussing articles In the field of Rheumatology

Here are the articles from Arthritis and Rheumatology

Diversity and epitope spreading of anti-RNA polymerase III antibodies in systemic sclerosis

Journal of Clinical Rheumatology

Contemporary Patterns of Financial Toxicity Among Patients With Rheumatologic Disease in the United States

Next we will be discussing articles In the field of Cardiology

Here are the articles from Circulation

Association of Urinary Metals With Cardiovascular Disease Incidence and All-Cause Mortality in the Multi-Ethnic Study of Atherosclerosis (MESA)

Journals of the American College of Cardiology

Serial Shock Severity Assessment Within 72 Hours After Diagnosis: A Cardiogenic Shock Working Group Report

JAMA Cardiology

Neighborhood Social Vulnerability and Premature Cardiovascular Disease in Haiti

Journal of Clinical Endocrinology & Metabolism

Moderate-intensity Combined Training Induces Lipidomic Changes in Individuals With Obesity and Type 2 Diabetes

Diabetes care

Circulating Metabolite Biomarkers of Glycemic Control in Youth-Onset Type 2 Diabetes

Neurology

Timing of Anticoagulation Resumption and Risk of Ischemic and Hemorrhagic Complications in Patients With ICH and Mechanical Heart Valves

Pulmonary and Critical care

Here are the articles from Chest

Nationwide Increasing Incidence of Nontuberculous Mycobacterial Diseases Among Adults in Denmark

The American Journal of Respiratory and Critical Care Medicine

Susceptible Young Adults and Development of Chronic Obstructive Pulmonary Disease Later in Life

Clinical Journal of American Society of Nephrology

Sodium Bicarbonate Treatment and Clinical Outcomes in Chronic Kidney Disease with Metabolic Acidosis: A Meta-Analysis

Kidney International reports

A Randomized Controlled Trial Comparing Automated Peritoneal Dialysis and Hemodialysis for Urgent-Start Dialysis in ESRD