Showing titles in History & Commentary

Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our evolutionary past, and why its growth is accelerated by technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues all around us, in patterns of wealth, health, power, and inequality.

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek, look down their hand-made microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering both forever. It is the fact that complex living organisms are assemblages of tiny self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christens them "cells".

Nearly two decades after it closed, the South Carolina State Hospital continues to hold a palpable mystique in Columbia and throughout the state. Founded in 1821 as the South Carolina Lunatic Asylum, it housed, fed, and treated thousands of patients incapable of surviving on their own. The patient population in 1961 eclipsed 6,600, well above its listed capacity of 4,823. By the mid-1990s, the patient population had fallen under 700, and the hospital had become a symbol of captivity, horror, and chaos.

Until the 1970s, if you suffered a medical crisis, your chances of survival were minimal. A 9-1-1 call might bring police or even the local funeral home. But that all changed with Freedom House EMS in Pittsburgh, a group of Black men who became America’s first paramedics and set the gold standard for emergency medicine around the world, only to have their story and their legacy erased—until now.

In 1900, the U.S. sent three doctors to Cuba to discover how yellow fever was spread. There, they launched one of history's most controversial human studies. Compelling and terrifying, The American Plague depicts the story of yellow fever and its reign in this country - and in Africa, where even today it strikes thousands every year. With "arresting tales of heroism," it is a story as much about the nature of human beings as it is about the nature of disease.

Picking up where Berton Roueche's The Medical Detectives left off, The Deadly Dinner Party presents 15 edge-of-your-seat, real-life medical detective stories written by a practicing physician. Award-winning author Jonathan Edlow, MD, shows the doctor as detective and the epidemiologist as elite sleuth in stories that are as gripping as the best thrillers.

Despite advances in health care, infectious microbes continue to be a formidable adversary to scientists and doctors. Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.

In this gripping narrative history, Laura Spinney traces the overlooked pandemic to reveal how the virus travelled across the globe, exposing mankind's vulnerability and putting our ingenuity to the test. As socially significant as both world wars, the Spanish flu dramatically disrupted - and often permanently altered - global politics, race relations, and family structures while spurring innovation in medicine, religion, and the arts.

While much has been written about the minds and methods of the medical professionals who save our lives, precious little has been said about their emotions. Physicians are assumed to be objective, rational beings, easily able to detach as they guide patients and families through some of life’s most challenging moments. But understanding doctors’ emotional responses to the life-and-death dramas of everyday practice can make all the difference on giving and getting the best medical care.

Viet Nam may be the only war we ever fought, or perhaps that was ever fought, in which the heroism of the American soldier was accompanied by humanitarianism unmatched in the annals of warfare. And the humanitarianism took place during the heat of the battle. The GI fixed as he fought, he cured and educated and built in the middle of the battle. He truly cared for, and about, those people. What other Army has ever done that? Humanitarianism was America's great victory in Viet Nam.

San Francisco's Laguna Honda Hospital is the last almshouse in the country, a descendant of the Hôtel-Dieu (God's hotel) that cared for the sick in the Middle Ages. Ballet dancers and rock musicians, professors and thieves - "anyone who had fallen, or, often, leapt, onto hard times" and needed extended medical care - ended up here. So did Victoria Sweet, who came for two months and stayed for 20 years. Laguna Honda, lower-tech but human-paced, gave Sweet the opportunity to practice a kind of attentive medicine that has almost vanished.

Much of what we know about the greatest medical disaster ever, the Black Plague of the fourteenth century, is wrong. The details of the Plague etched in the minds of terrified schoolchildren the hideous black welts, the high fever, and the final, awful end by respiratory failure are more or less accurate. But what the Plague really was, and how it made history, remain shrouded in a haze of myths.

African American Slave Medicine offers a critical examination of how African American slaves' medical needs were addressed during the years before and surrounding the Civil War. Drawing upon ex-slave interviews conducted during the 1930s and 1940s by the Works Project Administration (WPA), Dr. Herbert C. Covey inventories many of the herbal, plant, and non-plant remedies used by African American folk practitioners during slavery.

In 1866, 12 men and women and one small child were forced aboard a leaky schooner and cast away to a natural prison on the Hawaiian island of Molokai. Two weeks later, a dozen others were exiled, and then 40 more, and then 100 more. Tracked by bounty hunters and torn screaming from their families, the luckless were loaded into shipboard cattle stalls and abandoned in a lawless place where brutality held sway. Many did not have leprosy, and most of those who did were not contagious.

As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.

Despite passionate debates about health care and the media’s endless fascination with surgery, most of us have no idea how the first surgeons came to be because the story of surgery has never been fully told. Now, Empire of the Scalpel elegantly reveals surgery’s fascinating evolution from its early roots in ancient Egypt to its refinement in Europe and rise to scientific dominance in the United States.

It is 1919 and Elizabeth Hughes, the 11-year-old daughter of America's most-distinguished jurist and politician, Charles Evans Hughes, has been diagnosed with juvenile diabetes. It is essentially a death sentence. The only accepted form of treatment - starvation - whittles her down to 45 pounds, skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases - a miracle soon marred by scientific jealousy, intense business competition, and fistfights.

The Tudor dynasty died out because there was no heir of Elizabeth I's body to succeed her. Henry VIII, despite his six marriages, had produced no legitimate son who would live into old age. Three of the reigning Tudors (Edward VI, Mary I, and Elizabeth I) died without heirs apparent, the most tragic case being that of Mary Tudor, who went through two recorded cases of phantom pregnancy. If it were not for physical frailty and the lack of reproductive health among the Tudors, the course of history might have been different.

The story of poison is the story of power. For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family's spoons, tried on their underpants, and tested their chamber pots. Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions.