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For the last 100,000 years, humans have accumulated enormous power. But despite all our discoveries, inventions and conquests, we now find ourselves in an existential crisis. The world is on the verge of ecological collapse. Misinformation abounds. And we are rushing headlong into the age of AI – a new information network that threatens to annihilate us. If we are so wise, why are we so self-destructive? NEXUS considers how the flow of information has shaped us, and our world.

How can digital cash truly be "trustless"? What does it mean that blockchain offers a new paradigm of the "rule of code"? How are decisions made when a blockchain system faces an emergency, and who gets to make those decisions? In Blockchain Governance, Primavera De Filippi, Wessel Reijers, and Morshed Mannan offer answers to these questions and more, in an accessible, critical overview of legal and political issues related to blockchain technology.

As it absorbs data, gains agency, and intermediates between humans and reality, AI will help us to address enormous crises, from climate change to geopolitical conflicts to income inequality. It might well solve some of the greatest mysteries of our universe, revolutionize fields as diverse as medicine and architecture, and elevate the human spirit to unimaginable heights. But it will also pose challenges on a scale and of an intensity that we have never seen.

In this groundbreaking and provocative treatise, Alexander C. Karp, co-founder and chief executive officer of Palantir Technologies, and Nicholas W. Zamiska, head of corporate affairs at the company, offer a searing critique of our collective abandonment of creative and cultural ambition. They argue that in order for the West to maintain its geopolitical advantage—and the freedoms that we take for granted—the software industry must renew its commitment to addressing our most urgent challenges, including the new arms race of artificial intelligence.

While traditional drugs mostly help us manage the effects of disease, cell therapies promise genuine cures for a broad range of intractable ailments, from Alzheimer’s to heart damage to cancer. They could even reverse the effects of aging. For the first time in history, on an unprecedented scale, we possess the power to modify the biology that gives rise to disease, ultimately restoring individuals to a state of normalcy and reversing debilitating ailments. Former FDA Commissioner Scott Gottlieb traces the scientific achievements that propelled progress in cell therapies.