This is the introductory episode to our opening series on Antidepressants - Going Backwards with Dr. Ken Gillman.  We'll talk about how 1st line antidepressant medications have become less effective with time, how the diagnostic criteria for depression have been watered down, and reveal how Evidence-Based Medicine can be heavily manipulated.  We'll also give advice on how to best recognize subtypes of depression and treat them accordingly.  Dr. Gillman is an internationally well-known and well-recognized expert on diagnosing biologic depression and using MAOIs, a class of antidepressants widely used in the 1960s and 1970s but rarely used today, and is also one of, if not THE, leading expert on serotonin toxicity (improperly referred to as 'serotonin syndrome' by non-experts) and runs a website called psychotropical.com trying to shed light on these issues, as well as the historical and current problems with psychiatric and medical research.

Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at Renegadepsych@gmail.com and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website.

Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate.  This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

In this segment, Dr. Gillman tells us about his professional background and what makes him an expert on the subjects of depression and their most appropriate treatments.

Dr. Gillman is an internationally well-known and well-recognized expert on diagnosing biologic depression and using MAOIs, a class of antidepressants widely used in the 1960s and 1970s but rarely used today, and is also one of, if not THE, leading expert on serotonin toxicity (improperly referred to as 'serotonin syndrome' by non-experts) and runs a website called psychotropical.com trying to shed light on these issues, as well as the historical and current problems with psychiatric and medical research.

Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at Renegadepsych@gmail.com and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website.

Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate.  This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

In this section, Dr. Gillman talks about the origins of Randomized Controlled Trials and illuminates why we should be skeptical of 'so-called' Evidence-Based Medicine.  We also discuss why anecdotal data, or anec-data, aka deriving clinical practice recommendations and guidelines from our own experiences with patients and the drugs we prescribe them, is so important to developing as a good, effective prescribing clinician.

Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at Renegadepsych@gmail.com and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website.

Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate.  This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

In this segment, Dr. Gillman and I return to the drawing board and discuss on a very fundamental level, what depression is.  We talk about how the concept of and diagnosis of depression has been progressively watered down over the last 50 years, leading to more people being diagnosed and treated with SSRI antidepressants, which have very questionable efficacy and under-reported and under-recognized side effects.

Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at Renegadepsych@gmail.com and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website.

Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate.  This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

Dr. Gillman discusses the nuances between diagnosing biologic vs neurotic depression and tells us how to appropriately and effectively treat biologic depression, including his professional push to get more practitioners to utilize MAOIs.

Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at Renegadepsych@gmail.com and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website.

Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate. This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

Dr. Gillman gives us some fascinating historical background discussing the emergence of the medical publishing industry and its' relation to Robert Maxwell, the father of Ghislaine Maxwell (confidant of Jeffrey Epstein).  He talks about how decisons are driven by financial incentives and discusses how rating scales and data manipulation runs rampant in all of medicine, but especially in psychiatry, and how research can be very unreliable in the current publishing climate.

Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at Renegadepsych@gmail.com and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website.

Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate.  This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

In this segment, I start with a historical monologue on the history of depression and its' treatments throughout human history. Then, Dr. Gillman explains why it's so important to adequately treat depression with appropriate medications, despite sometimes having to manage a more severe side effect profile. He argues that the risk/benefit ratio, especially when biologic (vs. neurotic) depression is appropriately identified and diagnosed, oftentimes reveals greater benefit with MAOIs and TCAs than with SSRIs.

Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at Renegadepsych@gmail.com and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website.

Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate. This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

This will be a recurring segment where we try to garner a little bit of personal information about our guests, to give listeners a window into who the person behind the professional title is. Here, Ken talks about his experience with religion and his upbringing, as well as his role in launching 'the last advertisement for Tranylcypromine,' an MAOI medication. Hope you enjoyed this series on Antidepressants - Going Backwards.

Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at Renegadepsych@gmail.com and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website.

Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate. This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.