Is the future of medicine sweetened by the study of glycans? As GlycanHub rounds off its season, we've brought back the insights of 11 eminent scientists spanning from neuroscience to nanotechnology. Each guest delves into their vision of how glycans could shape medical advancements in their respective fields. Join Rina, our host, for a grand finale that paints a holistic picture of the promising horizon glycobiology is steering us towards.

Answers to the question: What role do you think glycans will play in the future of medicine relevant to your area of study? 

• Salome Pinho [01:21]  
• Olga Zaytseva [03:04]     
• Peter Joshi [03:51]    
• Hudson Freeze [05:11]   
• Samia Mora [06:11]      
• Anna Halama and Karsten Suhre [08:09]      
• Ronald Schnaar [12:03]      
• Gordon Lauc [14:49]    
• Louise Newson [17:35]      
• Vered Padler-Karavani [18:47]

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Please be advised that this show is for information only and should not be considered as a replacement or equal to medical advice. 

Could your steak dinner be tricking your immune system? In this episode we shed light on the connection between specific foods and colorectal cancer. Explore xeno-autoantigens, grasp the nuances of immunotherapy, and question the reliability of animal-derived heart valves. Vered Padler-Karavani is the principal investigator in the Department of Cell Research and Immunology at Tel Aviv University. Her research combines glycobiology, immunology, bio-nanotechnology, cancer research and xenotransplantation. Tune in to uncover the hidden connections between glycans, our diet, and the potential health repercussions.

We discuss: 

• Why study Glycobiology [01:35]
• Xeno-autoantigens & Xenosialitis [03:16]
• Where Does Neu5Gc Accumulate? [06:33]
• Red Meat & Colorectal Cancer [10:28]
• Tumor-associated Carbohydrate Antigens [11:54]
• Immunotherapy: Potential & Limitations [13:22]
• Animal-derived Heart Valves: Safety & Efficacy [20:02]
• Navigating Safety Regulations for Biologic Therapies [31:27] 
• Neu5Gc in Foods: The Gcemic Index [34:14]
• Does Prof. Vered Padler-Karavani Still Eat Red Meat? [37:23]
• Neu5Gc as Biomarkers [38:08]

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Please be advised that this show is for information only and should not be considered as a replacement or equal to medical advice. 

Does menopause hold implications beyond reproductive health? This episode reveals that the shift in hormonal balance affects inflammatory patterns, mediated by complex carbohydrates called glycans. We unravel the overlooked role of perimenopause in chronic disease onset and debunk common myths. Exploring hormone replacement therapy, we discuss its wider health impact, beyond mere symptom management. Louise Newson, a distinguished GP and Menopause Specialist, is the founder of the Balance App, The Menopause Charity, and the Newson Health Menopause Society. An active member of the UK Government Menopause Taskforce, she continually works to elevate menopause understanding and care.

Listen in as we discuss the potential of glycans as biomarkers for menopause, surpassing existing diagnostic tests in their predictive capacity.

We discuss: 

• Menopause Specialisation: Why Choose It? [02:11]
• Menopause: Myths vs. Facts [04:12]
• What Exactly Is Menopause? [05:33]
• Testosterone's Role in Female Health [08:04]
• Sex Hormones and Immune Regulation [09:18]
• Menopause and the Rise of Chronic Illness [12:36]
• Viewing Menopause as a Hormone Deficiency [15:22]
• Menopause and Metabolic Syndrome [16:57]
• Menopause and the Gut Microbiome [18:20]
• Oestrogen's Role in the Cardiovascular System [24:03]
• Is Perimenopause Contributing to Chronic Disease? [26:59]
• Limitations of Current Menopause Tests [30:53]
• Introducing the Balance App [32:00]
• Glycan-Based Menopause Tests [34:05]
• Addressing the Lack of Menopause Education in Medicine [35:36]
• Common Questions About Hormone Replacement Therapy [38:50]
• A Look at the Newson Clinic [41:26]

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Please be advised that this show is for information only and should not be considered as a replacement or equal to medical advice.