• Trade: Toradol
• Class: NSAID
• MOA: inhibits the production or prostaglandins in inflamed tissue, which decreases the responsiveness of pain receptors.
• Indications: Moderately severe acute pain
• Contraindications: Patients with a hx of peptic ulcer disease or GI bleed, patients with renal insufficiency, hypovolemic patients, 3rd trimester pregnancy, nursing mothers, allergy to other nsaids, stroke or head trauma, having surgery within the next 7 days.
• Side effects: headache, drowsiness, dizziness, abdominal pain, dyspepsia, N/V, Diarrhea.
• Dosing:

Adult

IV 30mg

IM 60mg

Senior (65 and older)/ Pediatric < 50kgs

IV 15mg

IM 30mg

• Trade: Morphine
• Class: Opiate agonist/Narcotic Analgesic 
• MOA: Binds to the opiate receptors. Reduces stimulation of the sympathetic nervous system caused by pain and anxiety. Reduction of sympathetic stimulation reduces heart rate, cardiac work, and myocardial O2 consumption
• Indications: moderate to severe pain including chest pain associated with ACS, CHF, and pulmonary edema.
• Contraindications: Respiratory depression, shock.
• Side effects: Respiratory depression, hypotension, N/V, dizziness, lightheadedness, sedation, diaphoresis, euphoria, seizures, cardiac arrest, anaphylactoid reaction.
• Dosage:

Adult  

2-10mg IV/IO/IM

Pediatric 

< 110 lbs 0.025 – 0.2mg/kg IV/IO/IM

• Trade: Sublimaze
• Class: Narcotic Analgesic 
• MOA: Binds to opiate receptors producing analgesia and euphoria
• Indication: Pain
• Contraindication: Use caution in traumatic brain injury, Respiratory depression 
• Side effects: Respiratory depression, apnea, hypotension, N/V, dizziness, sedation euphoria, Sinus bradycardia, sinus tachycardia, palpitations, HTN, diaphoresis, syncope
• Dosing

Adult 

50-100mcg IM/IV

Pedi 

1-2mcg/kg IM/IV