When studying TRAIL expression in the tumour stroma, Dr Massimiliano Mazzone and Dr Carla Riera-Domingo made a surprising discovery with great therapeutic potential: this immunoregulator acts as a gatekeeper of the vasculature at the pre-metastatic niche. Listen to this episode to find out what implications this has for the formation of the premetastatic niche and the therapeutic value this novel finding holds.

You can also read the full episode transcript here: magazine.eacr.org/the-role-of-trail-in-premetastatic-niche-formation-in-breast-cancer-episode-11-of-the-cancer-researcher-podcast

This study has been published in Science Advances 9 (12), eadd5028. DOI: 10.1126/sciadv.add5028 and was included in the EACR's Highlights in Cancer Research.

In this episode we continue our exploration of gender diversity in cancer research with Johanna Joyce, Marisol Soengas, and Mireia Crispin Ortuzar. Drawing from the challenges discussed in the previous episode, they discuss practical measures to break the glass ceiling for women in cancer research.

They share insights into the importance of supportive networks, mentorship, and the involvement of both men and women in addressing gender disparities. Join us on this journey through statistics, personal experiences, and practical solutions, as we remain dedicated to breaking barriers and promoting equity in cancer research.

In this episode, we engage in a dynamic discussion on gender diversity in cancer research with guests Johanna Joyce, Marisol Soengas, and Mireia Crispin Ortuzar. Exploring challenges faced by women in science, they address the leaky pipeline, postdoc instability, and the importance of fostering inclusive work environments.

Our guests share valuable insights into the need for tailored diversity strategies, supportive networks, and representation at higher career levels in tackling gender disparities. Join us as we navigate through statistics, personal experiences, and practical solutions, working to break barriers and promote equality in cancer research.