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For Blood and Money
- Billionaires, Biotech, and the Quest for a Blockbuster Drug
- Narrado por: Rob Shapiro
- Duración: 8 h y 33 m
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Grandes primeros Títulos
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Resumen del Editor
A gripping business narrative and scientific thriller about what it takes to bring a wonder drug to market—and save countless lives.
For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.
In the multibillion-dollar business of biotech, where pharmaceutical companies, the government, hedge funds, and venture capitalists have spent billions on funding, experimentation, and treatments, a single molecule can stop cancer in its tracks—and make the people who find that rare molecule astonishingly rich. For Blood and Money follows a small team at a biotech start-up in California, who have found one of these rare molecules. Their compound, known as a BTK inhibitor, seems to work on a vicious type of leukemia. When patients start rising from their hospice beds, the team knows they’re onto something big.
What follows is a story of genius, pathos, and drama, in which vivid characters navigate a world of corporate intrigue and ambiguous morality. Vardi’s narrative immerses listeners in the recent explosion of biotech start-ups. He describes the scientists, doctors, and investors who are risking everything to develop new, life-saving treatments, and introduces suffering patients for whom the stakes are life-or-death. A gripping nonfiction listen, For Blood and Money illustrates why it’s so hard to bring new drugs to market, explains why they are so expensive, and examines how profit-driven venture capitalists are shaping the future of medicine.
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- De: Donald R. Kirsch PhD, Ogi Ogas PhD
- Narrado por: James Foster
- Duración: 7 h y 35 m
- Versión completa
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The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity - by chewing, brewing, and snorting - some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the 5,000-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze Age medicine, a worm-killing birch fungus, knotted to his leggings.
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Aargh!
- De Curmud the prof en 05-20-17
De: Donald R. Kirsch PhD, y otros
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The Billion Dollar Molecule
- One Company's Quest for the Perfect Drug
- De: Barry Werth
- Narrado por: Stephen Bowlby
- Duración: 18 h y 25 m
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Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.
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Book is interesting but narrator is not
- De Alexa en 05-05-23
De: Barry Werth
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From Breakthrough to Blockbuster
- The Business of Biotechnology
- De: Donald L. Drakeman, Lisa N. Drakeman, Nektarios Oraiopoulos
- Narrado por: Chris Andrew Ciulla
- Duración: 7 h y 1 m
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Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. From Breakthrough to Blockbuster focuses on both the companies themselves and the broader biotech ecosystem that supports them.
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Wonderful book!
- De Momo Abbasi en 04-28-24
De: Donald L. Drakeman, y otros
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Genentech
- The Beginnings of Biotech
- De: Sally Smith Hughes
- Narrado por: Suzie Althens
- Duración: 7 h y 12 m
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In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading. Coming at a time of economic recession and declining technological competitiveness in the United States, the event ignited a period of speculative frenzy over biotechnology.
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Shallow and lifeless
- De LTS en 11-26-23
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The Antidote
- Inside the World of New Pharma
- De: Barry Werth
- Narrado por: Sean Pratt
- Duración: 16 h y 27 m
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In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.
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For me this was not interesting
- De Yan en 06-26-17
De: Barry Werth
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Bottle of Lies
- The Inside Story of the Generic Drug Boom
- De: Katherine Eban
- Narrado por: Katherine Eban
- Duración: 14 h y 26 m
- Versión completa
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From an award-winning Fortune reporter, an explosive narrative investigation of the generic drug boom that reveals the life-threatening dangers posed by globalization - The Jungle for pharmaceuticals.
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overbearing self-righteous indignation
- De VB en 01-13-20
De: Katherine Eban
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The Drug Hunters
- The Improbable Quest to Discover New Medicines
- De: Donald R. Kirsch PhD, Ogi Ogas PhD
- Narrado por: James Foster
- Duración: 7 h y 35 m
- Versión completa
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General
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Narración:
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Historia
The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity - by chewing, brewing, and snorting - some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the 5,000-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze Age medicine, a worm-killing birch fungus, knotted to his leggings.
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Aargh!
- De Curmud the prof en 05-20-17
De: Donald R. Kirsch PhD, y otros
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Pharma
- Greed, Lies, and the Poisoning of America
- De: Gerald Posner
- Narrado por: Jacques Roy
- Duración: 22 h y 55 m
- Versión completa
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Pharmaceutical breakthroughs such as antibiotics and vaccines rank among some of the greatest advancements in human history. Yet, exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on prescription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning with a monolithic industry.
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Great book, but with some issues
- De Irina en 06-12-20
De: Gerald Posner
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Drugs and the FDA
- Safety, Efficacy, and the Public's Trust
- De: Mikkael A. Sekeres
- Narrado por: Mike Lenz
- Duración: 8 h y 40 m
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Food and Drug Administration approval for COVID-19 vaccines and the controversial Alzheimer's drug Aduhelm made headlines, but few of us know much about how the agency does its work. Why is the FDA the ultimate United States authority on a drug's safety and efficacy? In Drugs and the FDA, Mikkael Sekeres—a leading oncologist and former chair of the FDA's cancer drug advisory committee—tells the story of how the FDA became the most trusted regulatory agency in the world.
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Metastic
- De Anne E. Sharman en 05-07-23
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An Elegant Defense
- The Extraordinary New Science of the Immune System: A Tale in Four Lives
- De: Matt Richtel
- Narrado por: Fred Sanders
- Duración: 12 h y 33 m
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A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.
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Weak foundation, good conclusion
- De David en 03-24-19
De: Matt Richtel
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The Breakthrough
- Immunotherapy and the Race to Cure Cancer
- De: Charles Graeber
- Narrado por: Will Collyer, Charles Graeber
- Duración: 7 h y 7 m
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Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.
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Surprisingly gripping
- De Kari Niles en 01-21-19
De: Charles Graeber
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- De: Thomas Hager
- Narrado por: Angelo Di Loreto
- Duración: 8 h y 39 m
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- De C. White en 03-08-19
De: Thomas Hager
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The Song of the Cell
- An Exploration of Medicine and the New Human
- De: Siddhartha Mukherjee
- Narrado por: Dennis Boutsikaris
- Duración: 16 h y 3 m
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From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.
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Beyond Words Wonderful
- De Lynn en 11-27-22
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Dopesick
- De: Beth Macy
- Narrado por: Beth Macy
- Duración: 10 h y 16 m
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In this extraordinary work, Beth Macy takes us into the epicenter of a national drama that has unfolded over two decades. From the labs and marketing departments of big pharma to local doctor's offices; wealthy suburbs to distressed small communities in Central Appalachia; from distant cities to once-idyllic farm towns; the spread of opioid addiction follows a tortuous trajectory that illustrates how this crisis has persisted for so long and become so firmly entrenched.
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Useful, but recommend Dreamland instead
- De Sarah en 08-27-18
De: Beth Macy
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The Truth About the Drug Companies
- How They Deceive Us and What to Do About It
- De: Marcia Angell
- Narrado por: Kate Reading
- Duración: 7 h y 14 m
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In this explosive expose of the drug companies and how they are ripping us off, Marcia Angell, M.D., a doctor, medical journalist, and a former editor of the respected New England Journal of Medicine, reveals the many ways in which the pharmaceutical industry has moved away from its original purpose of finding and producing useful new drugs.
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Pronunciation
- De Greg en 05-22-07
De: Marcia Angell
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Bad Pharma
- How Drug Companies Mislead Doctors and Harm Patients
- De: Ben Goldacre
- Narrado por: Jonathan Cowley
- Duración: 11 h y 54 m
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Medicine is broken. We like to imagine that it's based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry.
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A must read for health professionals
- De zerodynamics en 03-01-13
De: Ben Goldacre
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Immune
- A Journey into the Mysterious System That Keeps You Alive
- De: Philipp Dettmer
- Narrado por: Steve Taylor
- Duración: 10 h y 28 m
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You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.
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Steve Taylor for the win
- De Bay Area Engineer en 11-02-21
De: Philipp Dettmer
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Superconvergence
- How the Genetics, Biotech, and AI Revolutions Will Transform our Lives, Work, and World
- De: Jamie Metzl
- Narrado por: James Anderson Foster, Jamie Metzl
- Duración: 15 h y 44 m
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Leading futurist and OneShared.World founder Jamie Metzl explores how genome sequencing, gene editing, artificial intelligence, and other technologies are not only changing our lives, but catalyzing each other in radical and accelerating ways. These technologies have the potential to improve our health, feed billions of people, supercharge our economies, and store essential information for millions of years, but can also—if we are not careful—do immeasurable harm.
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Great Book Somewhat Spoiled by Self-Promotion
- De Jack E. Koepke en 06-22-24
De: Jamie Metzl
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Pain Killer
- An Empire of Deceit and the Origin of America's Opioid Epidemic
- De: Barry Meier
- Narrado por: Ray Porter
- Duración: 6 h y 42 m
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Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma’s aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. Meanwhile, the drugmaker’s owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin.
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Infuriating and Compelling
- De TiffanyD en 12-24-18
De: Barry Meier
Lo que los oyentes dicen sobre For Blood and Money
Calificaciones medias de los clientesReseñas - Selecciona las pestañas a continuación para cambiar el origen de las reseñas.
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- Gregory S Young
- 10-18-23
Entertaining and informative
I really enjoyed the book. Educational about cancer and tech investing. We’ll performed as well.
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- Darcy
- 03-01-23
Really enjoyed this title
A great story at the intersection of cutting edge medical science, high -stakes finance, and human personalities and foibles. I found it fascinating to get an inside view on the development of new drugs, whose failures often exceed their promise, while many others sit on shelves waiting for often serendipitous discovery by financiers and corporations.
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- J. Muscato
- 02-23-23
Interesting story hampered by incorrect pronunciation
As a hematologist the story of the real world of venture capitalism in the production of this outstanding drug was interesting and disturbing. The docs doing the real work were cast aside because of finance kings- very unfair. The story was hampered by incorrect pronunciation of specific scientific terms (such as the initial mentions of tyrosine kinases and the organization ASH) which would have been easily corrected if the narrator (who is good otherwise) did this in the presence of a person in the field.
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- Patrick Meng-Frecker
- 05-25-24
the sums of money will blow your mind
it was an important story to tell about modern drug development. it's interesting to hear how hedgefunds and investors make massively expensive drug trials possible sometimes taking huge losses but this time making an enormous windfall.
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- Marina Edler
- 01-20-23
Fascinating look into the ecosystem and politics of drug development
Vardi gives a detailed account of the harrowing story of the grit and perseverance of scientists and investors as they put everything on the line to bring an elegant molecule in a novel class of class of cancer medicines to patients with little alternative. Amazing testament to what people can achieve when they work together. The money involved is mind boggling and not something that I personally focus on, but it is a clear driver for many involved. Highly recommended.
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- Anonymous User
- 04-10-24
a close view of the biotechnology industry
Was riveted by the story of the Ceos and the researchers. I never realized that it is a ruthless field.
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- VL
- 05-23-24
Amazing Ride Through the World of Biotech
Really interesting story with lots of twists and turns as the story unfolds of how two blockbuster drugs were delivered to market.
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- Nishant Gupta
- 07-15-23
Captivating!
Great storyline and narration! The story started slow but really picked up pace over the chapters!
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- ItsBeenReal
- 10-24-23
Great true and timely story of our broken system
Whatever a page turner is for audio...this is it. I am an insider in the industry, and to me this was as good as any action movie.
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- Alena
- 07-26-23
Excellent book about biotech
This is an excellent book with enough storytelling depicting the biotech business reality. As a biotech employee I enjoyed it a lot
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