Today Dr. Beth and I discuss hormone optimization, foundational principals of longevity, longevity therapies and so much more!

About Dr. Beth

Beth McDougall, MD has been in practice for more than 25 years and is an internationally recognized Integrative physician with a specialty in multifactorial degenerative disease. Prior to Jyzen, she founded Clear Center of Health where she built a successful integrative medical practice dedicated to personalized medicine. Long known as a medical detective, Dr. McDougall excels at unraveling complex, multifactorial conditions. At Jyzen, she is advancing a new medical paradigm, one at the intersection of medicine, technology and contemporary physics, with the goal of transforming the practice of medicine. As the Chief Medical Officer of Kenobi, Dr. McDougall leads a portfolio of companies developing energetic, diagnostic and healing technologies based in resonance physics. She sits on the advisory board for the Energy Medicine University and the scientific advisory board for the Resonance Science Foundation.

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Today I am speaking with Dr. Leigh Erin Connealy, MD. Dr. Connealy is absolutely amazing, and I was so interested to have her on the podcast because of her incredible experience and philosophy on cancer prevention.

We discuss cancer rates, what she recommends for preventing cancer, cancer early diagnostics, how she treats patients in her clinics and much more.

If you are interested in joining my Female Longevity Optimization Group, ⁠learn more here: https://www.skool.com/femalelongevityoptimization/about About Dr Connealy: Leigh Erin Connealy, M.D. is a prominent leader in the field of Integrative Medicine. She utilizes the best of all sciences, including conventional, homeopathic, eastern medicine and modern medicine. She is the Medical Director of Cancer Center for Healing and Center for New Medicine. The combined 30,000 S.F. clinics have become the largest integrative medical clinic in North America, and have been visited by over patients 47,000 patients. Dr. Connealy's Website: https://www.connealymd.com/ Dr. Connealy's Instagram: https://www.instagram.com/connealymd/ Timestamps: 00:00 Introduction and Background 06:13 Taking a Holistic Approach to Healthcare 11:04 The Rise of Cancer and the Health of Children 31:39 Reducing the Risk of Cancer: Lifestyle Recommendations 32:09 Preparing the Body for Pregnancy and Raising Healthy Children 33:07 The Importance of Sleep, Water, and Reducing Plastic Use 35:21 Exercise and Mindful Eating for Optimal Health 37:18 Addressing Emotional Well-being and Trauma 46:19 Early Cancer Detection Methods: Full Body MRIs and Liquid Biopsies 52:30 A Comprehensive Approach to Cancer Treatment

Today I am speaking with Carolina Reis Oliveira, OneSkin Co-Founder & CEO.

We discuss the importance of addressing the root cause of skin aging and the role of senescent cells in the aging process. We also talk about the skin barrier and how it can become compromised. Carolina shares her thoughts on retinol and the importance of listening to your skin's reaction to products. OneSkin measures skin aging through the epigenetic signature of the skin. OneSkin has developed a peptide called OS1 that has been shown to reduce the age of the skin by 2.5 years in humans. The peptide works by reducing the load of senescent cells and promoting collagen production. OneSkin is constantly researching and developing new products to target skin aging and are exploring the potential of using their peptide for other inflammatory conditions. OneSkin believes in the importance of staying at the forefront of scientific research and innovation to provide the most effective products for skin aging.

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ABOUT CAROLINA
Fascinated with biology from a young age, Carolina knew she’d have a future in science. A fearless leader with a passion for longevity and living life to the fullest, she embarked on an ambitious goal — to delay the onset of age-related diseases by targeting aging itself. This led her to earn degrees in stem cell biology and tissue engineering, and a doctorate in immunology. Then, determined to translate her academic achievements into real-world impact, Carolina left her native Brazil for Silicon Valley, co-founding OneSkin in 2016. As Chief Executive Officer, Carolina and her team spearhead research and development, creating molecules that target cellular aging, including their pioneering innovation, the OS-01 peptide.

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Chapters
00:00 Carolina's Background and Interest in Skin Health

03:03 The Impact of Aging on Health and Disease

11:45 Targeting Senescent Cells for Reversing Damage

13:12 The Importance of the Skin Barrier

26:08 Investing in Long-Term Skin Health

30:00 Measuring Skin Aging and the Use of Devices

36:24 Sun Exposure and SPF Recommendations

40:12 The Age-Reversing Effects of OS1 Peptide

45:19 The Potency of the Eye Cream for Delicate Skin

48:28 Exploring the Potential of the Peptide for Inflammatory Conditions

50:48 Future Possibilities: Supplements and Injectables

52:37 Red Light Therapy and Personal Protocol

55:29 Staying at the Forefront of Scientific Research and Innovation

59:21 DISCLAIMER

I am speaking with Christian Drapeau, inventor of a plant-based stem cell product for health and longevity, Stemregen.

Christian is more than a scientist; he’s a stem cell expert and herbalist, pioneering plant-based stem cell enhancers. Yes, plants and stem cells together! His background from McGill University and work at Stemtech International make him a leading voice in stem cell science.

His book, ‘Cracking the Stem Cell Code,’ reveals how our bodies use stem cells for repair, and his latest research shows how aquatic plants can boost stem cell production, like nature’s own fountain of youth.

We’ll explore how Christian’s journey in ancient herbalism led to innovative discoveries in stem cell enhancement and clarify the difference between traditional procedures and products like STEMREGEN.

Today I am sitting down with my friend, Dave Asprey. Dave is the father of Biohacking and has been a friend and mentor for years. We discuss all things longevity and biohacking!

About Dave:

Dave Asprey is best known as the founder of Bulletproof Coffee and the entire Biohacking movement. As a four-time New York Times bestselling author, CEO of Upgrade Labs, and host of a Webby award-winning, top 100 podcast, The Human Upgrade (formerly Bulletproof Radio), Dave is a maverick in the entrepreneurial health science and biotechnology space.
As a true pioneer, Dave was the first person to ever sell a product online, and of course, it was related to coffee. He sold caffeine t-shirts out of his dorm room before the web browser was even invented which earned him a profile in Entrepreneur Magazine. Dave became an early internet technology journalist, cyber security expert, and co-founded a division of Exodus Communications, a company that seeded the internet we know today.
At only 28 years old, Dave’s phenomenal career success left him battling cognitive fog, arthritis, pre-diabetes, put him at high risk for stroke, and with the biochemistry of a 60-year-old. His own premature aging launched him on a quest to reclaim his health and vitality, lose over 100 pounds, and not only reverse his biological age but increase his IQ by over 12 points! This work led him to create The Bulletproof Diet and to coin the health science term “biohacking,” a word once deemed “fringe” yet now resides in the Merriam Webster dictionary, along with Dave Aprey as part of the definition.
Dave's relentless pursuit of human potential drove him to invest nearly $2 million in upgrading his biology and run the world's first and largest biohacking conference, earning him the title "Father of Biohacking." You’ve seen him featured in Men's Health, the Today Show, Wired, Good Morning America, the New York Times, Fast Company, and many other major publications. Forbes named his company one of the top 20 most innovative brands in the world, and he’s credited with creating three unique billion-dollar markets: MCT Oil, Collagen Protein, and Functional Coffee.
Dave’s mission is to help people upgrade to a happier, more conscious state, one cell at a time.
As the founder of 40 Years of Zen, Dave applies neuroscience to personal transformation. 40 Years of Zen is the world's most exclusive five-day intensive for upgrading the brain. Attracting Hollywood celebrities, C-suite executives, professional athletes, and other global elite, Dave’s programs are leading human evolution.
Dave divides his time between Vancouver Island, BC, and Austin, Texas, enjoying time with his two children while sharing dad jokes that never fail to induce groans and eye-rolls!

Today Dr. Killen and I discuss hormone optimization and hormone replacement therapy (HRT) for women. She explains that HRT can start in perimenopause, around the age of 35-40, and involves replacing hormones like progesterone, testosterone, and estrogen to maintain optimal levels. She emphasizes the importance of personalized dosing and using bioidentical hormones rather than synthetic versions. Dr. Killen also highlights the benefits of HRT, including improved libido, motivation, skin health, fat burning, and muscle building. She recommends regular hormone testing and discusses the different types of hormone administration, such as creams and injections. Additionally, she addresses the issue of polycystic ovarian syndrome (PCOS) and the importance of early detection and treatment. In this conversation, Dr. Killen and Kayla Barnes discuss various topics related to women's health, including hormone replacement therapy (HRT), polycystic ovarian syndrome (PCOS), longevity supplements, sexual health, and skin health. They also touch on the importance of vitamin D and sun exposure, as well as the potential benefits of cold plunging.

00:00 Introduction and Background

02:24 Hormone Replacement Therapy (HRT)

08:08 The Importance of Testosterone in Women

11:48 Finding a Doctor Knowledgeable in Hormones

13:41 Bioidentical Hormones vs. Synthetic Hormones

21:01 Polycystic Ovarian Syndrome (PCOS)

24:40 The Benefits of Hormone Replacement Therapy (HRT) for Women

25:36 Understanding Polycystic Ovarian Syndrome (PCOS)

34:04 Exploring Longevity Supplements for Women

41:36 Improving Sexual Health in Women

44:24 The Importance of Vitamin D and Sun Exposure

45:20 Cold Plunging for Women's Health

About Dr. Killen

Dr. Amy Killen is a leading anti-aging and regenerative physician.

After working as a board-certified emergency physician for more than seven years, Dr. Killen saw the effects of unchecked, chronic disease and on her patients and decided to transition into anti-aging and longevity medicine in hopes of offering her patients alternatives to the traditional aging paradigm.

An international speaker, clinical practice owner, entrepreneur, author, and frequent media guest, Dr Killen has become an outspoken advocate for empowering people to look and feel their best by merging lifestyle modification, integrative medicine, body-identical hormones, nutritional supplements, energy modalities and stem cell therapies.
In her clinical practice, Dr Killen and her colleague, Dr Harry Adelson, pioneered the Full Body Stem Cell Makeover, one of the most innovative regenerative procedures currently available. In her portion of the procedure, Dr Killen combines stem cell injections with light, sound and other energy-based therapies to give patients unparalleled synergistic regenerative effects for skin, hair and sexual systems.

Dr. Killen is also the founder of the Human Optimization Project (www.HOPbox.life), a dynamic monthly subscription longevity supplement system and educational platform.
She is a founding member of Nof1+ (Nof1plus.com), incentivizing data-driven self-experimentation by leveraging community AI insights.
Dr. Killen co-founded Humanaut Health, a tech-enabled longevity clinic franchise.

Save on Hopbox with code KAYLA.

Today I am speaking with my friend, Dr. Molly Maloof on female sexual health, the science backing of love and much more!

If you are interested in joining my Female Longevity Optimization Group, learn more here!

About Dr. Molly Maloof

Dr. Molly Maloof has dedicated her medical practice to health optimization and personalized medicine since 2011 and has worked with high-achieving entrepreneurs, investors, and technology executives in Silicon Valley as well as Academy Award winners in Los Angeles. Since 2012, she has worked as an advisor or consultant to over 50 companies in the digital health, consumer health, and biotechnology industries. She published The Spark Factor, the first book on biohacking for women, with Harper Wave Books in January 2023. She taught a pioneering course on healthspan extension in the Wellness Department of the Medical School at Stanford University for three years before launching her own company, Adamo Bioscience. The vision of her company is to demonstrate that love is embodied medicine that enhances longevity and awakens a healthier, happier, and more resilient world where intimacy is the undisputed force for human flourishing. Dr. Maloof is on the frontier of personalized medicine, digital health technologies, biofeedback-assisted lifestyle interventions, psychedelic medicine, sexual wellness, and science-backed wellness products and services.

Vist Molly's Website HERE

Molly's IG

Timestamps

00:00Introduction and Background of Dr. Molly Maloof0

7:05 The Lack of Education and Resources for Women's Sexual Health

14:06 The Importance of Love and Relationships in Health Optimization

29:02 The Interplay Between Hormones and Women's Sexual Desire

31:29 Preventing Breast Cancer and Hormone Replacement Therapy

34:48 Understanding the Phases of the Menstrual Cycle

38:39 Fertility and Planning for Parenthood

42:59 Challenges of Maintaining a Healthy Diet in a Toxic Environment

49:41 Optimal Diet for Women: Personalized Approaches

Today I am speaking with Dr. Jin-Xiong She about all thing NAD+, we discuss what it is, how to measure your NAD+ levels, what impact your NAD+ levels have on your health and longevity, how to optimize your NAD+ levels and so much more!

Use code KAYLA to save on all NAD+ optimization products !

About Dr. Dr. Jin-Xiong She

Dr. Jin-Xiong She received his college education in China and PhD degree in France. After a short postdoctoral training at the University of Florida (UF), he was quickly promoted to Assistant Professor, Associate Professor, Full and Endowed Professor. He served as Division Chief of Experimental Pathology and Director of Research of the UF’s world-class Diabetes Center. Dr. She was recruited in 2002 to be the Georgia Research Alliance Eminent Scholar in Genomic Medicine at the Medical College of Georgia. He was the founding Director of the Center for Biotechnology and Genomic Medicine, Professor of the Departments of Obstetrics and Gynecology and Department of Health Technologies as well as the director of two core research facilities for Augusta University (Genomics, Proteomics & Mass Spectrometry). In his long academic career, he has authored over 400-peer reviewed papers with an H-Index of 76 and over 19,000 citations, secured over $100 million in research grants, has been invited to speak globally. He mentored a large number of doctoral students, post-docs and faculty members. Dr. She is one of the 20 “Georgia Top Medical Researchers”. He served as President of the Chinese Geneticists in America and President of the American Diabetes Association’s council on Immunology, transplantation and Immunogenetics among other honors. Dr. She is a serial entrepreneur and has founded or co-founded multiple companies in the US and China. He is the founder and CEO of Jinfiniti Precision Medicine, a company dedicated to optimizing healthspan through biomarker testing and precision nutraceuticals. More information can be found on Jin-Xiong She’ LinkedIn Profile and Jin-Xiong She’s Google Scholar Profile. Boying DunPhD, co-Founder & Chief Innovation OfficerBob ThordarsonChief Technology OfficerMichael HeckPhD, CLIA Clinical Laboratory Director