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With the potential to diagnose some brain illnesses 7 years before their onset, Optical Coherence Tomography can do a lot more than checking eye health. JuneBrain was founded to improve remote assessments and monitoring of neurological and retinal diseases. They provide telehealth devices and AI software solutions. Their products are user-friendly, portable, and adaptable for clinical and point-of-care settings. Their vision is to improve health outcomes for individuals with eye and brain diseases by expanding access to healthcare across the globe.

In this episode, Dr Sam, CEO of JuneBrain shares her inspirational journey; alongside some of the personal health issues she has faced. Great Listen!!

Timestamp:

00:00 Intro

02:12 Journey Leading to JuneBrain

06:40 What is Optical Coherence Tomography? (OCT)

08:23 Applications of OCT

10:20 Motivating Factors for JuneBrain

13:00 Results vs Traditional OCT

14:00 Description of the Neuro-i SS-OCT

15:00 Approval Stage and Focus

18:00 Raising Funding

20:15 Tips on raising Capital for a start-up

23:00 Thoughts on the Future of OCT and Healthcare

26:30 Predicted cost of JuneBrain’s Neuro-i SS-OCT

29:30 What is Postural Orthostatic Tachycardia Syndrome? Or Neurally Mediated Syncope?

Interesting Reads:

Parkinson's detection in the eye:

- Euronews Article

https://www.euronews.com/health/2023/08/22/eye-scans-could-detect-signs-of-parkinsons-disease-7-years-before-diagnosis#:~:text=Using%20eye%20scan%20data%20and,diagnosed%2C%20new%20research%20has%20revealed.

- The actual journal article

https://www.neurology.org/doi/10.1212/WNL.0000000000207727

- Myasthenia Gravis (MG)

https://my.clevelandclinic.org/health/diseases/17252-myasthenia-gravis-mg

- Postural Orthostatic Tachycardia Syndrome (POTS)

https://my.clevelandclinic.org/health/diseases/16560-postural-orthostatic-tachycardia-syndrome-pots

- NEURALLY MEDIATED SYNCOPE

https://www.vumc.org/autonomic-dysfunction-center/neurally-mediated-syncope

JuneBrain Website:

https://www.junebrain.com

Ways to Support the Podcast:

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Advancements in Genetic Engineering have opened a wide avenue for new approaches to medical imaging. In this exciting episode, Rodney sat with two postgraduate students at The Technical University of Munich, Felipe Navarro and Nika Kobetic. They are taking part in iGEM Competition this year in Paris, France. Their project involves working on RNA that will make sick human cells glow, opening a huge array of eventualities to the future of medical imaging.

Timestamp:
00:00 Genetic Engineering Capabilities
02:39 Intro
04:35 Background Information
07:50 What is the iGEM competition?
12:16 RNA-based recording
22:10 What is CRISPR
28:45 Why RNA and not DNA
32:22 What is Epigenetics
33:30 Feasibility of CRISPR worldwide
38:11 Ethical Considerations for CRISPR
43:42 Biggest myths in synthetic biology
49:55 Future of Synthetic Biology
54:55 Mendelian Genetics

iGEM: https://igem.org

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Spinally Medical is a pioneering medical technology company specializing in the development of advanced SCS lead, which is implanted intrathecally (in the subarachnoid space), with no surgical incision. Spinally is founded by group of doctors and business executives, with the aim to enhance the quality of life for individuals suffering from chronic pain, by providing high quality spinal cord stimulation and recording. In addition to its effectiveness in pain management, SCS has shown promising results in treatments for various neurological disorders, such as post-stroke rehabilitation, neuro-restoration, angina pectoris, spasticity, and Parkinson’s Disease.

Spinally Website:
https://www.spinallymedical.com

Spinally Crowd Funding Link:
https://capitalcell.es/en/campaign/spinally/

Timestamp:
00:00 Intro
02:20 Dr Carles Intro
06:00 What is Pain?
08:00 Problems with Chronic Pain and solutions using Spinal Cord Stimulation
16:19 Simplified explanation of Spinal Cord Stimulation
18:12 Implanted Pulse Generator location and life expectancy
25:00 Clinical Efficacy
29:00 Animal Models
33:20 Path to market
34:20 Future of Pain treatment
38:00 Difficulty of Implantation
41:10 Crowd Funding and contact

Support the show

Follow or Connect with Rodney Moses:
Instagram | LinkedIn | YouTube |

Donations
Patreon | PayPal