• Mind Control with Lasers: Optical Recording Part II

  • May 13 2022
  • Length: 1 hr and 44 mins
  • Podcast

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Mind Control with Lasers: Optical Recording Part II

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  • Welcome back to Neurotech Pub!This episode is part two of a two part series on optical methods for recording and stimulating neural activity. Our guests on this episode are Elizabeth Hillman, PhD,  Mark Schnitzer, PhD, and Jacob Robinson, PhD. Last time we talked about optical recording methods, but in this episode we focus on optical stimulation methods. Cheers!Check out video and full transcript here: https://www.paradromics.com/podcast/episode-12-mind-control-with-lasers00:00 | Intro1:37 | Aspirational Papers1:56 | Packer Lab 2:10 | What is the claustrum?2:30 | Ian's paper (but only part of it!)3:02 | Two-Photon Bidirectional Control and Imaging In Vivo3:29 | Inferring Spikes from Calcium Imaging5:45 | Neuropixels are now in humans7:12 | Paper by Pachitariu et al 7:55 | Ian Oldenburg10:02 | Kaufman Lab11:21 | Cortical activity in the null space: permitting preparation without movement12:08 | Motor cortical dynamics shaped by multiple distinct subspaces during naturalistic behavior12:33 | Tickling Cells with Light14:41 | Light-activated ion channels for remote control of neuronal firing14:50 | Remote Control of Behavior through Genetically Targeted Photostimulation of Neurons15:20 | Millisecond-timescale, genetically targeted optical control of neural activity16:03 | Red-shifted Opsins16:52 | eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications17:26 | Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor18:16 | Neural Dust18:41 | Wireless magnetothermal deep brain stimulation19:05 | Neural Stimulation Through Ultrasound19:20 | Methods and Modalities: Sculpting Light21:35 | Recent advances in patterned photostimulation for optogenetics22:50 | Two-photon microscopy is now over 30 years old (Denk 1990)25:22 | Optical Recording State of the Art27:06 | Challenges of Deep Tissue 2-Photon Imaging28:21 | Deisseroth Lab28:29 | Temporal Precision of Optical Stimulation29:09 | Simultaneous all-optical manipulation and recording 30:40 | Targeted Ablation in Somatosensory Cortex 33:29 | Commercially Available Fast Opsins34:41 | Recent paper from Deisseroth Lab41:17 | Cortical layer–specific critical dynamics triggering perception42:21 | The Utah Array from Blackrock Neurotech44:52 | Principles of Corticocortical Communication50:43 | The Cost of Cortical Computation51:27 | Behaviour-dependent recruitment of long-range projection neurons in somatosensory cortex (2013) | Spatiotemporal convergence and divergence in the rat S1 "barrel" cortex (1987) | Diverse tuning underlies sparse activity in layer 2/3 vibrissal cortex of awake mice (2019) 52:56 | Gollisch and Meister 200853:22 | Spike Timing-Dependent Plasticity (STDP)1:05:09 | Neurotech Pub Episode 11 -  Let There Be Light1:05:20 | Forecasting the Future1:05:41 | Temporally precise single-cell-resolution optogenetics1:06:16 | Large Scale Ca++ Recordings from Vaziri Lab1:07:11 | Cohen Lab1:07:19 | All Optical Electrophysiology 1:14:19 | Emiliani et al 20151:16:33 | All-Optical Interrogation of Neural Circuits1:16:53 | Mice Strains @ Jackson Lab1:17:00 | The Allen Institute1:20:39 | Neuroscience and Engineering Collaborations1:18:39 | Nicolas Pegard1:18:47 | Adesnik Lab1:24:41 | Shenoy, Sahani, and Churchland 20131:24:52 | Dimensionality reduction for large-scale neural recordings1:25:17 | Matlab: Understanding Kalman Filters1:25:58 | Two-photon excitation microscopy1:26:37 | Emiliani Lab Holography course1:26:57 | Optics by Eugene Hecht1:28:05 | Intro to Optics Course1:29:41 | What the Heck Is a Claustrum?1:33:53 | Cortical activity in the null space: permitting preparation without movement1:34:33 | Neural Manifolds and Learning1:35:19 | Locked-in Syndrome1:36:58 | Sabatini Lab1:37:07 | Probing and regulating dysfunctional circuits using DBS1:39:36 | Sliman Bensmaia | Nicho Hatsopoulos1:39:43 | The science and engineering behind sensitized brain-controlled bionic hands1:41:20 | Michael Long's singing rodents1:42:12 | Engram1:43:06 | Chang Lab1:43:19 | Tim Gardner | Michale FeeWant more? Follow Paradromics & Neurotech Pub on Twitter  Follow Matt A, Ian, Adam, & Matt K on Twitter
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