Episodes

  • NEJM This Week — July 18, 2024

    NEJM This Week — July 18, 2024
    Jul 17 2024
    Featuring articles on tenecteplase for ischemic stroke within 4.5 to 24 hours after the stroke, risankizumab vs. ustekinumab for Crohn’s disease, nirmatrelvir–ritonavir as Covid-19 postexposure prophylaxis, and efanesoctocog alfa in children with hemophilia A; a review article on the management of insomnia; a case report of a woman with postpartum fever, abdominal pain, and skin ulcers; and Perspectives on the ethics of relational AI, on anticipating the next pandemic, and on a first patient.
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    30 mins
  • NEJM This Week — July 11, 2024

    NEJM This Week — July 11, 2024
    Jul 10 2024
    Featuring articles on semaglutide and chronic kidney disease in type 2 diabetes, felzartamab in kidney-transplant rejection, bulevirtide and peginterferon for chronic hepatitis D, and nirsevimab and hospitalization for RSV bronchiolitis; a review article on malnutrition in adults; a case report of an infant with vomiting and hypercalcemia; and Perspectives on Medicare Advantage and consolidation’s new frontier, on orphan drugs and priorities for the future, on funding post-authorization vaccine-safety science, and on standing on her own two feet.
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    36 mins
  • NEJM This Week — July 4, 2024

    NEJM This Week — July 4, 2024
    Jul 3 2024
    Featuring articles on stress ulcer prophylaxis during invasive mechanical ventilation, new therapies for hereditary angioedema, tissue factor–directed therapy in cervical cancer, and normalization of C1 inhibitor in a patient with hereditary angioedema; a review article on acute abdomen in the modern era; a Clinical Problem-Solving article on aggregating the loose threads; a Medicine and Society on a case for the Medical Civil Rights Act; and Perspectives on academic freedom in America; on water pollution, health, and medicine’s duty to engage; and on to forgive, divine.
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    32 mins
  • NEJM This Week — June 27, 2024

    NEJM This Week — June 27, 2024
    Jun 26 2024
    Featuring articles on treatments for eosinophilic esophagitis, reteplase versus alteplase for acute ischemic stroke, dupilumab for COPD with type 2 inflammation, and brigatinib in NF2-related schwannomatosis; a review article on amyloidosis; a case report of a man with recurrent fever and liver lesions; and Perspectives on Alzheimer’s disease, biomarkers, and mAbs; on climate litigation for protecting public health; on carbon-footprint analyses in RCTs; and on the phantom of the organ.
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    34 mins
  • NEJM This Week — June 20, 2024

    NEJM This Week — June 20, 2024
    Jun 19 2024
    Featuring articles on combination therapy for diffuse large B-cell lymphoma, autosomal dominant Alzheimer’s disease, noninvasive ventilation for preoxygenation during emergency intubation, a novel anti-CD38 antibody in immune thrombocytopenia, and a glucose-responsive insulin for type 2 diabetes; a review article on congenital and acquired Chiari syndrome; a case report of a man with arthritis and rash; and Perspectives on ethics and innovative research on brain diseases, on sustaining and scaling up street medicine, and on the maternal crossroad.
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    33 mins
  • NEJM This Week — June 13, 2024

    NEJM This Week — June 13, 2024
    Jun 12 2024
    Featuring articles on T-cell cancer after CAR T-cell therapy, the early diagnosis and treatment of COPD and asthma, and the implications of race adjustment in lung-function equations; a review article on diets; a case report of a woman with the worst headache of her life; and Perspectives on efforts toward equity and on feeling guilty.
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    28 mins
  • NEJM This Week — June 6, 2024

    NEJM This Week — June 6, 2024
    Jun 5 2024
    Featuring articles on neoadjuvant immunotherapy for dMMR colon cancer, TAVR in patients with a small aortic annulus, gene editing and retinal degeneration, and the genetic diagnosis of rare diseases; a review article on disorders of magnesium; a case report of a woman with metastatic breast cancer; and a Perspective on malicious midwives, fruitful vines, and bearded women.
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    24 mins
  • NEJM This Week — May 30, 2024

    NEJM This Week — May 30, 2024
    May 29 2024
    Featuring articles on aficamten for obstructive hypertrophic cardiomyopathy; early blood-pressure reduction in acute stroke; interferon-γ in autoimmune polyendocrine syndrome type 1; video laryngoscopy for intubation in neonates; hunger, thirst, and Buridan’s ass; and global health law for a safer and fairer world; a review article on medical AI and human values; a case report of a man with a pustular rash; and Perspectives on an approach toward a tobacco-free generation, on fair allocation of GLP-1 and dual GLP-1–GIP receptor agonists, on corporate medicine 2.0, and on snapshots.
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    40 mins