Vi har snakket med Elin Hoffman Dahl, infeksjonsmedisiner og ph.d.-stipendiat som er på vei til utbruddet i DR Kongo. Elin har vært med på å håndtere flere Ebola-utbrudd de siste årene og deler erfaringer fra disse og siste oppdateringer rundt det aktuelle utbruddet.

Lenke til en av erfaringene Elin har delt:

https://www.aftenposten.no/meninger/kronikk/i/5pJXv6/en-litt-annerledes-hyllest-til-erling-braut-haaland

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Ebola er et høyaktuelt tema i disse dager med det pågående utbruddet i DR Kongo. For å gi litt mer bakgrunn gjør vi en historisk reise fra oppdagelsen av Ebola frem til i dag.

Referanser:

• https://www.gov.uk/government/publications/ebola-overview-history-origins-and-transmission/ebola-overview-history-origins-and-transmission
• https://time.com/3548047/first-ebola-outbreak-history/
• https://en.wikipedia.org/wiki/Kivu_Ebola_epidemic
• https://en.wikipedia.org/wiki/Western_African_Ebola_epidemic
• https://en.wikipedia.org/wiki/Ebola
• https://www.who.int/news-room/fact-sheets/detail/ebola-disease
• https://journals.physiology.org/doi/full/10.1152/ajplung.00354.2014
• https://www.sciencedirect.com/science/article/pii/S1286457905001437

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Ingrid, Jørgen og Nikolai oppsummerer etter beste evne årets ESCMID (en av verdens største infeksjonsmedisinske konferanser) og vårmøtet (kanskje en av verdens minste infeksjonskonferanser) i denne reporasje-baserte episoden av Pestpodden.

Referanser:

1. White NM, et al. Effectiveness of oral care for the prevention of non-ventilator hospital-acquired pneumonia (HAPPEN): a multicentre, stepped-wedge, cluster-randomised trial in Australia. Lancet Infect Dis. 2026.

2. Israelsen SB, et al. Short-course antibiotic therapy of 5 days in community-acquired pneumonia (CAP5): study protocol for a randomised controlled trial. BMJ Open. 2023;13:e069013. doi: 10.1136/bmjopen-2022-069013.

3. Chanderraj R, et al. Mortality of Patients With Sepsis Administered Piperacillin-Tazobactam vs Cefepime. JAMA Intern Med. 2024;184(7):769-77.

4. Azevedo LCP, et al. Using the 2026 Surviving Sepsis Campaign Guidelines in Practice. Crit Care Sci. 2026;38:e20260036.

5. Doumat G, et al. Short Versus Longer Antibiotic Duration for Community-Acquired Pneumonia : A Multicenter Target Trial Emulation. Ann Intern Med. 2026;179(5):629-36.

6. Overdevest AG, et al. Antibiotic treatment for 1 day versus 4–7 days in patients with acute cholangitis after adequate endoscopic biliary drainage (COBRA): study protocol for a randomized controlled trial. Trials. 2026. doi: 10.1186/s13063-026-09524-7. PubMed: PMID 41689066.

7. Turner NA, et al. Dalbavancin for Treatment of Staphylococcus aureus Bacteremia: The DOTS Randomized Clinical Trial. JAMA. 2025.

8. Kristensen LH, et al. Diagnostic accuracy of dipsticks for urinary tract infections in acutely hospitalised patients: a prospective population-based observational cohort study. BMJ Evid Based Med. 2025;30(1):36-44.

9. Giamarellos-Bourboulis EJ, et al. Precision Immunotherapy to Improve Sepsis Outcomes: The ImmunoSep Randomized Clinical Trial. JAMA. 2026;335(9):775-86.

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Meslinger har vært en fryktet og hyppig forekommende sykdom opp gjennom historien. I moderne tid og med effektiv vaksine falt forekomsten – men i senere år har man sett stadig flere tilfeller (og utbrudd), inkludert i Europa og USA. Ingrid, Jørgen og Nikolai snakker seg gjennom meslinger «fra tidenes morgen» og frem til i dag. Bli med på reisen!

Og - for infeksjonsmedisinsk helsepersonell som lytter til episoden våren 2025 - her er lenke til påmelding NSCMID: Home - NSCMID 2025.

Referanser:

1. Roald Dahl, 1986: “Measles: A dangerous disease” (open letter to parents).

2. Hübschen JM, et al. Measles. Lancet. 2022;399(10325):678-90.

3. Berche P. History of measles. Presse Med. 2022;51(3):104149.

4. Petrova VN, et al. Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles. Sci Immunol. 2019;4(41).

5. Mina MJ, et al. Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens. Science. 2019;366(6465):599-606.

6. Belongia EA, Naleway AL. Smallpox vaccine: the good, the bad, and the ugly. Clin Med Res. 2003;1(2):87-92.

8. Madsen KM, et al. A population-based study of measles, mumps, and rubella vaccination and autism. N Engl J Med. 2002;347(19):1477-82.

10.Holzmann H, et al. Eradication of measles: remaining challenges. Med Microbiol Immunol. 2016;205(3):201-8.

11.Jafri SK, et al. Subacute sclerosing panencephalitis - current perspectives. Pediatric Health Med Ther. 2018;9:67-71.

12. de Swart RL, et al. Rinderpest eradication: lessons for measles eradication? Curr Opin Virol. 2012;2(3):330-4.

13.Kim TH, et al. Vaccine herd effect. Scand J Infect Dis. 2011;43(9):683-9.

14.Doll MK, Correira JW. Revisiting the 2014-15 Disneyland measles outbreak and its influence on pediatric vaccinations. Hum Vaccin Immunother. 2021;17(11):4210-5.

13.Nuwarda RF, et al. Vaccine Hesitancy: Contemporary Issues and Historical Background. Vaccines (Basel). 2022;10(10).

16.Minta AA, Ferrari M, Antoni S, et al. Progress Toward Measles Elimination — Worldwide, 2000–2023. MMWR Morb Mortal Wkly Rep 2024;73:1036–1042.

17.State School Immunization Requirements and Vaccine Exemption Laws, CDC 2022,State School Immunization Requirements and Vaccine Exemption Laws

18.Epidemiologi meslinger UK og Europa: https://www.gov.uk/government/publications/measles-epidemiology-2023, European Region reports highest number of measles cases in more than 25 years – UNICEF, WHO/Europe

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